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In recent days, Convolutional Neural Networks (CNN) have demonstrated impressive performance in medical image analysis. However, there is a lack of clear understanding of why and how the Convolutional Neural Network performs so well for…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Jyoti Islam , Yanqing Zhang

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

Neurons and Cognition · Quantitative Biology 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim

As the second most common neurodegenerative disease, Parkinson's disease has caused serious problems worldwide. However, the cause and mechanism of PD are not clear, and no systematic early diagnosis and treatment of PD have been…

Signal Processing · Electrical Eng. & Systems 2022-01-12 Shujie Wang , Gongshu Wang , Guangying Pei

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Early diagnosis of Alzheimer's disease is a challenge because the existing methodologies do not identify the patients in their preclinical stage, which can last up to a decade prior to the onset of clinical symptoms. Several research…

Machine Learning · Computer Science 2024-01-03 Vivek Kumar Tiwari , Premananda Indic , Shawana Tabassum

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

Machine Learning · Computer Science 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

We firstly simulated disease dynamics by KAN (Kolmogorov-Arnold Networks) nearly 4 years ago, but the kernel functions in the edge include the exponential number of infected and discharged people and is also in line with the…

Neural and Evolutionary Computing · Computer Science 2024-06-04 Jun-Bo Tao , Bai-Qing Sun , Wei-Dong Zhu , Shi-You Qu , Jia-Qiang Li , Guo-Qi Li , Yan-Yan Wang , Ling-Kun Chen , Chong Wu , Yu Xiong , Jiaxuan Zhou

Recent studies have demonstrated that the representations of artificial neural networks (ANNs) can exhibit notable similarities to cortical representations when subjected to identical auditory sensory inputs. In these studies, the ability…

Neurons and Cognition · Quantitative Biology 2024-12-23 Taketo Akama , Zhuohao Zhang , Pengcheng Li , Kotaro Hongo , Hiroaki Kitano , Shun Minamikawa , Natalia Polouliakh

More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Audrey Paleczny , Shubham Parab , Maxwell Zhang

Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Ángel de la Vega Jiménez

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…

Machine Learning · Computer Science 2025-04-29 Rumeng Li , Xun Wang , Dan Berlowitz , Brian Silver , Wen Hu , Heather Keating , Raelene Goodwin , Weisong Liu , Honghuang Lin , Hong Yu

As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…

Machine Learning · Computer Science 2025-11-05 Rajan Das Gupta , Md Kishor Morol , Nafiz Fahad , Md Tanzib Hosain , Sumaya Binte Zilani Choya , Md Jakir Hossen

Alzheimer's disease (AD) is a neurodegenerative disease known to affect brain functional connectivity (FC). Linear FC measures have been applied to study the differences in AD by splitting neurophysiological signals such as…

Neurons and Cognition · Quantitative Biology 2022-06-14 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

Human-Computer Interaction · Computer Science 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

Schizophrenia (SZ) is a prevalent mental disorder characterized by cognitive, emotional, and behavioral changes. Symptoms of SZ include hallucinations, illusions, delusions, lack of motivation, and difficulties in concentration. Diagnosing…

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

Machine Learning · Computer Science 2026-03-06 Nishan Mitra

Depression is a public health issue which severely affects one's well being and cause negative social and economic effect for society. To rise awareness of these problems, this publication aims to determine if long lasting effects of…

Machine Learning · Computer Science 2022-02-09 Egils Avots , Klavs Jermakovs , Maie Bachmann , Laura Paeske , Cagri Ozcinar , Gholamreza Anbarjafari