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In this work, we explore the Transcriptomics Atlas pipeline adapted for cost-efficient and high-throughput computing in the cloud. We propose a scalable, cloud-native architecture designed for running a resource-intensive aligner -- STAR --…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-17 Piotr Kica , Sabina Lichołai , Michał Orzechowski , Maciej Malawski

The application of serverless computing for alignment of RNA-sequences can improve many existing bioinformatics workflows by reducing operational costs and execution times. This work analyzes the applicability of serverless services for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-08 Piotr Kica , Michał Orzechowski , Maciej Malawski

Iterative improvement of model architectures is fundamental to deep learning: Transformers first enabled scaling, and recent advances in model hybridization have pushed the quality-efficiency frontier. However, optimizing architectures…

Machine Learning · Computer Science 2024-11-28 Armin W. Thomas , Rom Parnichkun , Alexander Amini , Stefano Massaroli , Michael Poli

We introduce Stardust, a compiler that compiles sparse tensor algebra to reconfigurable dataflow architectures (RDAs). Stardust introduces new user-provided data representation and scheduling language constructs for mapping to…

Programming Languages · Computer Science 2022-11-08 Olivia Hsu , Alexander Rucker , Tian Zhao , Kunle Olukotun , Fredrik Kjolstad

RRAM crossbars have been studied to construct in-memory accelerators for neural network applications due to their in-situ computing capability. However, prior RRAM-based accelerators show efficiency degradation when executing the popular…

Hardware Architecture · Computer Science 2024-02-01 Yifeng Zhai , Bing Li , Bonan Yan , Jing Wang

Large language models (LLMs) rely on self-attention for contextual understanding, demanding high-throughput inference and large-scale token parallelism (LTPP). Existing dynamic sparsity accelerators falter under LTPP scenarios due to…

Hardware Architecture · Computer Science 2025-12-25 Huizheng Wang , Taiquan Wei , Hongbin Wang , Zichuan Wang , Xinru Tang , Zhiheng Yue , Shaojun Wei , Yang Hu , Shouyi Yin

We present a case study of a cloud-based computational workflow for processing large astronomical data sets from the Murchison Widefield Array (MWA) cosmology experiment. Cloud computing is well-suited to large-scale, episodic computation…

Instrumentation and Methods for Astrophysics · Physics 2021-03-04 Ruby Byrne , Daniel Jacobs

We introduce STAR (Stream Transduction with Anchor Representations), a novel Transformer-based model designed for efficient sequence-to-sequence transduction over streams. STAR dynamically segments input streams to create compressed anchor…

Computation and Language · Computer Science 2025-05-22 Weiting Tan , Yunmo Chen , Tongfei Chen , Guanghui Qin , Haoran Xu , Heidi C. Zhang , Benjamin Van Durme , Philipp Koehn

Point clouds are increasingly important in intelligent applications, but frequent off-chip memory traffic in accelerators causes pipeline stalls and leads to high energy consumption. While conventional line buffer techniques can eliminate…

Hardware Architecture · Computer Science 2025-07-01 Yu Feng , Zheng Liu , Weikai Lin , Zihan Liu , Jingwen Leng , Minyi Guo , Zhezhi He , Jieru Zhao , Yuhao Zhu

Cloud infrastructure supports the efficient operation of data pipelines regarding requirements like cost, speed, and resource utilization. We present an integrated view of optimization opportunities for cloud-based data pipelines by…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-03 Johannes Jablonski , Georg-Daniel Schwarz , Philip Heltweg , Dirk Riehle

This paper presents a solution to efficiently explore the design space of communication adapters. In most digital signal processing (DSP) applications, the overall architecture of the system is significantly affected by communication…

Hardware Architecture · Computer Science 2007-06-13 Cyrille Chavet , Philippe Coussy , Pascal Urard , Eric Martin

In this paper we describe the development of a streamlined framework for large-scale ATLAS pMSSM reinterpretations of LHC Run-2 analyses using containerised computational workflows. The project is looking to assess the global coverage of…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-07 Marco Donadoni , Matthew Feickert , Lukas Heinrich , Yang Liu , Audrius Mečionis , Vladyslav Moisieienkov , Tibor Šimko , Giordon Stark , Marco Vidal García

Cloud computing is a powerful new technology that is widely used in the business world. Recently, we have been investigating the benefits it offers to scientific computing. We have used three workflow applications to compare the performance…

Instrumentation and Methods for Astrophysics · Physics 2015-03-17 G. Bruce Berriman , Ewa Deelman , Gideon Juve , Moira Regelson , Peter Plavchan

Much like on-premises systems, the natural choice for running database analytics workloads in the cloud is to provision a cluster of nodes to run a database instance. However, analytics workloads are often bursty or low volume, leaving…

Databases · Computer Science 2019-11-27 Matthew Perron , Raul Castro Fernandez , David DeWitt , Samuel Madden

I/O performance is crucial to efficiency in data-intensive scientific computing; but tuning large-scale storage systems is complex, costly, and notoriously manpower-intensive, making it inaccessible for most domain scientists. To address…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-27 Chris Egersdoerfer , Philip Carns , Shane Snyder , Robert Ross , Dong Dai

In this paper, we present STAR, a new distributed in-memory database with asymmetric replication. By employing a single-node non-partitioned architecture for some replicas and a partitioned architecture for other replicas, STAR is able to…

Databases · Computer Science 2019-07-23 Yi Lu , Xiangyao Yu , Samuel Madden

This paper presents a solution to efficiently explore the design space of communication adapters. In most digital signal processing (DSP) applications, the overall architecture of the system is significantly affected by communication…

Hardware Architecture · Computer Science 2007-06-20 Cyrille Chavet , Philippe Coussy , Pascal Urard , Eric Martin

Performance of distributed optimization and learning systems is bottlenecked by "straggler" nodes and slow communication links, which significantly delay computation. We propose a distributed optimization framework where the dataset is…

Machine Learning · Statistics 2018-03-15 Can Karakus , Yifan Sun , Suhas Diggavi , Wotao Yin

Astronomical photometry is the science of measuring the flux of a celestial object. Since its introduction, the CCD has been the principle method of measuring flux to calculate the apparent magnitude of an object. Each CCD image taken must…

Instrumentation and Methods for Astrophysics · Physics 2015-02-11 Paul Doyle

As organizations increasingly migrate their applications to the cloud, the optimization of microservices architectures becomes imperative for achieving sustainability goals. Nonetheless, sustainable deployments may increase costs and…

Software Engineering · Computer Science 2024-09-24 Vittorio Cortellessa , Daniele Di Pompeo , Michele Tucci
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