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Modern statisticians are often presented with hundreds or thousands of hypothesis testing problems to evaluate at the same time, generated from new scientific technologies such as microarrays, medical and satellite imaging devices, or flow…

Applications · Statistics 2008-12-18 Bradley Efron

A hypothesis testing algorithm is replicable if, when run on two different samples from the same distribution, it produces the same output with high probability. This notion, defined by by Impagliazzo, Lei, Pitassi, and Sorell [STOC'22],…

Data Structures and Algorithms · Computer Science 2025-09-05 Anders Aamand , Maryam Aliakbarpour , Justin Y. Chen , Shyam Narayanan , Sandeep Silwal

As a common step in refining their scientific inquiry, investigators are often interested in performing some screening of a collection of given statistical hypotheses. For example, they may wish to determine whether any one of several…

Methodology · Statistics 2022-03-04 Adam Elder , Marco Carone , Peter Gilbert , Alex Luedtke

The classical binary hypothesis testing problem is revisited. We notice that when one of the hypotheses is composite, there is an inherent difficulty in defining an optimality criterion that is both informative and well-justified. For…

Statistics Theory · Mathematics 2021-03-29 Michael Bell , Yuval Kochman

We provide an interpretation of entanglement based on classical correlations between measurement outcomes of complementary properties: states that have correlations beyond a certain threshold are entangled. The reverse is not true, however.…

Quantum Physics · Physics 2015-05-26 Lorenzo Maccone , Dagmar Bruss , Chiara Macchiavello

A new method based on the rejection sampling for finding statistical tests is proposed. This method is conceptually intuitive, easy to implement, and applicable for arbitrary dimension. To illustrate its potential applicability, three…

Methodology · Statistics 2026-03-11 Markku Kuismin

Generalizations to the permutation test are introduced to allow for situations in which the null model is not exchangeable. It is shown that the generalized permutation tests are exact, and a partial converse: that any test function that is…

Methodology · Statistics 2018-09-03 Jeffrey Roach , William Valdar

Cluster analysis is a fundamental research issue in statistics and machine learning. In many modern clustering methods, we need to determine whether two subsets of samples come from the same cluster. Since these subsets are usually…

Machine Learning · Computer Science 2025-07-15 Xinying Liu , Lianyu Hu , Mudi Jiang , Simeng Zhang , Jun Lou , Zengyou He

Increasing accessibility of data to researchers makes it possible to conduct massive amounts of statistical testing. Rather than follow a carefully crafted set of scientific hypotheses with statistical analysis, researchers can now test…

Genomics · Quantitative Biology 2016-09-08 Olga A. Vsevolozhskaya , Chia-Ling Kuo , Gabriel Ruiz , Luda Diatchenko , Dmitri V. Zaykin

Testing hypotheses is an issue of primary importance in the scientific research, as well as in many other human activities. Much clarification about it can be achieved if the process of learning from data is framed in a stochastic model of…

Data Analysis, Statistics and Probability · Physics 2007-05-23 G. D'Agostini

Hypothesis testing is a central statistical method in psychological research and the cognitive sciences. While the problems of null hypothesis significance testing (NHST) have been debated widely, few attractive alternatives exist. In this…

Methodology · Statistics 2020-06-08 Riko Kelter , Julio Michael Stern

We consider the problem of hypothesis testing in the situation when the first hypothesis is simple and the second one is local one-sided composite. We describe the choice of the thresholds and the power functions of the Score Function test,…

Statistics Theory · Mathematics 2015-02-26 Serguei Dachian , Yury Kutoyants , Lin Yang

The Einstein Equivalence Principle (EEP) is of crucial importance to test the foundations of general relativity. When the particles involved in the test exhibit quantum properties, it is unknown whether this principle still holds. A…

Quantum Physics · Physics 2024-10-10 Carlo Cepollaro , Flaminia Giacomini

Usually one compares the accuracy of two competing classifiers via null hypothesis significance tests (nhst). Yet the nhst tests suffer from important shortcomings, which can be overcome by switching to Bayesian hypothesis testing. We…

Machine Learning · Computer Science 2016-11-23 Giorgio Corani , Alessio Benavoli , Janez Demšar , Francesca Mangili , Marco Zaffalon

Based on an analysis of the inference rules used, we provide a characterization of the situations in which classical provability entails intuitionistic provability. We then examine the relationship of these derivability notions to uniform…

Logic in Computer Science · Computer Science 2016-08-31 Gopalan Nadathur

The theocratical properties of the power of the conventional testing hypotheses and the selection bias are usually unknown under covariate-adaptive randomized clinical trials. In the literature, most studies are based on simulations. In…

Statistics Theory · Mathematics 2021-05-04 Li-Xin Zhang

In this work we study the phenomenon of self-testing from the first principles, aiming to place this versatile concept on a rigorous mathematical footing. Self-testing allows a classical verifier to infer a quantum mechanical description of…

Scientific claims gain credibility by replicability, especially if replication under different circumstances and varying designs yields equivalent results. Aggregating results over multiple studies is, however, not straightforward, and when…

Methodology · Statistics 2023-12-27 Thom Benjamin Volker , Irene Klugkist

Unnormalized probability distributions are frequently used in machine learning for modeling complex data generating processes. Though Markov chain Monte Carlo (MCMC) algorithms can approximately sample from unnormalized distributions,…

Methodology · Statistics 2026-04-29 Alexander Dombowsky , Barbara E. Engelhardt , Aaditya Ramdas

In the evaluation of treatment effects, it is of major policy interest to know if the treatment is beneficial for some and harmful for others, a phenomenon known as qualitative interaction. We formulate this question as a multiple testing…

Methodology · Statistics 2017-08-29 Qingyuan Zhao , Dylan S. Small , Weijie Su