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Based on recent experiments with time-lapse fluorescent imaging, we propose a cellular automaton model for the dynamics of vascular endothelial cells (ECs) in angiogenic morphogenesis. The model successfully reproduces cell mixing behavior,…

Cellular Automata and Lattice Gases · Physics 2015-07-22 Keisuke Matsuya , Hiroki Kurihara , Tetsuji Tokihiro

The cellular automaton model is used to simulate diffusion and aggregation with dissociation of point particles in 2D. A continuous phase transition is found that separates creation of compact aggregates and fractal ones. The transition is…

Computational Physics · Physics 2015-04-17 Yuriy G. Gordienko , Elena E. Zasimchuk

Computational neuroscience relies on large-scale dynamical-systems models of neurons, with a vast amount of offline, pre-simulation, tuned parameters, with models often tied to their brain simulators. These fixed parameters lead to stiff…

Neurons and Cognition · Quantitative Biology 2025-12-25 Lennart P. L. Landsmeer , Mario Negrello , Said Hamdioui , Christos Strydis

Studying cell morphology changes in time is critical to understanding cell migration mechanisms. In this work, we present a deep learning-based workflow to segment cancer cells embedded in 3D collagen matrices and imaged with phase-contrast…

Computer Vision and Pattern Recognition · Computer Science 2021-12-17 Estibaliz Gómez-de-Mariscal , Hasini Jayatilaka , Özgün Çiçek , Thomas Brox , Denis Wirtz , Arrate Muñoz-Barrutia

We motivate and derive the dynamical rules for a computationally feasible three-dimensional cellular automaton model of snow crystal growth. The model improves upon points of weak physical connections identified in other similar models…

Materials Science · Physics 2013-08-23 James G. Kelly , Everett C. Boyer

Artistic stylization of 3D volumetric smoke data is still a challenge in computer graphics due to the difficulty of ensuring spatiotemporal consistency given a reference style image, and that within reasonable time and computational…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Dongqing Wang , Ehsan Pajouheshgar , Yitao Xu , Tong Zhang , Sabine Süsstrunk

Recently simulation methods have been developed for optical tactile sensors to enable the Sim2Real learning, i.e., firstly training models in simulation before deploying them on the real robot. However, some artefacts in the real objects…

Robotics · Computer Science 2021-12-06 Tudor Jianu , Daniel Fernandes Gomes , Shan Luo

Traditionally, diagnosis and treatment of fungal infections in humans depend heavily on face-to-face consultations or examinations made by specialized laboratory scientists known as mycologists. In many cases, such as the recent…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Camilo Javier Pineda Sopo , Farshid Hajati , Soheila Gheisari

In this work, we introduce a novel computational framework that we developed to use numerical simulations to investigate the complexity of brain tissue at a microscopic level with a detail never realised before. Directly inspired by the…

Medical Physics · Physics 2018-06-20 Marco Palombo , Daniel C. Alexander , Hui Zhang

We investigate using reinforcement learning agents as generative models of images (extending arXiv:1804.01118). A generative agent controls a simulated painting environment, and is trained with rewards provided by a discriminator network…

Computer Vision and Pattern Recognition · Computer Science 2019-10-03 John F. J. Mellor , Eunbyung Park , Yaroslav Ganin , Igor Babuschkin , Tejas Kulkarni , Dan Rosenbaum , Andy Ballard , Theophane Weber , Oriol Vinyals , S. M. Ali Eslami

This paper presents a constructive algorithm that achieves successful one-shot learning of hidden spike-patterns in a competitive detection task. It has previously been shown (Masquelier et al., 2008) that spike-timing-dependent plasticity…

Neurons and Cognition · Quantitative Biology 2017-08-31 Toby Lightheart , Steven Grainger , Tien-Fu Lu

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

Soft Condensed Matter · Physics 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

Many patterns in nature exhibit self-similarity: they can be compactly described via self-referential transformations. Said patterns commonly appear in natural and artificial objects, such as molecules, shorelines, galaxies and even images.…

Machine Learning · Computer Science 2022-04-19 Michael Poli , Winnie Xu , Stefano Massaroli , Chenlin Meng , Kuno Kim , Stefano Ermon

Motivation: Networks underlie the generation and interpretation of many biological datasets: gene networks shed light on the regulatory structure of the genome, and cell networks can capture structure of the tumor micro-environment.…

Machine Learning · Statistics 2026-03-18 Bailey Andrew , Erica L. Harris , James A. Poulter , David R. Westhead , Luisa Cutillo

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

Applied Physics · Physics 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

Image extrapolation aims at expanding the narrow field of view of a given image patch. Existing models mainly deal with natural scene images of homogeneous regions and have no control of the content generation process. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Yijun Li , Lu Jiang , Ming-Hsuan Yang

Stem cells, through their ability to produce daughter stem cells and differentiate into specialized cells, are essential in the growth, maintenance, and repair of biological tissues. Understanding the dynamics of cell populations in the…

Applications · Statistics 2026-02-02 Huyen Nguyen , Haim Bar , Zhiyi Chi , Vladimir Pozdnyakov

Cell segmentation in microscopy is a challenging problem, since cells are often asymmetric and densely packed. This becomes particularly challenging for extremely large images, since manual intervention and processing time can make…

Image and Video Processing · Electrical Eng. & Systems 2019-06-19 Mahsa Lotfollahi , Sebastian Berisha , Leila Saadatifard , Laura Montier , Jokubas Ziburkus , David Mayerich

Generative models, such as GANs and diffusion models, have been used to augment training sets and boost performances in different tasks. We focus on generative models for cell detection instead, i.e., locating and classifying cells in given…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Chen Li , Xiaoling Hu , Shahira Abousamra , Meilong Xu , Chao Chen

Many creative multimedia systems are built upon visual primitives such as strokes or textures, which are difficult to collect at scale and fundamentally different from natural image data. This data scarcity makes it challenging for modern…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Dantong Qin , Alessandro Bozzon , Xian Yang , Xun Zhang , Yike Guo , Pan Wang