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Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiazheng Wang , Zeyu Liu , Min Liu , Xiang Chen , Xinyao Yu , Yaonan Wang , Hang Zhang

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Zekang Chen , Jia Wei , Rui Li

The substantial modality-induced variations in radiometric, texture, and structural characteristics pose significant challenges for the accurate registration of multimodal images. While supervised deep learning methods have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Xiaochen Wei , Weiwei Guo , Wenxian Yu

Current approaches for deformable medical image registration often struggle to fulfill all of the following criteria: versatile applicability, small computation or training times, and the being able to estimate large deformations.…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Hanna Siebert , Lasse Hansen , Mattias P. Heinrich

Multi-modal registration is a required step for many image-guided procedures, especially ultrasound-guided interventions that require anatomical context. While a number of such registration algorithms are already available, they all require…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Viktoria Markova , Matteo Ronchetti , Wolfgang Wein , Oliver Zettinig , Raphael Prevost

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Accurate intraoperative image guidance is critical for achieving maximal safe resection in brain tumor surgery, yet neuronavigation systems based on preoperative MRI lose accuracy during the procedure due to brain shift. Aligning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Reuben Dorent , Laura Rigolo , Colin P. Galvin , Junyu Chen , Mattias P. Heinrich , Aaron Carass , Olivier Colliot , Demian Wassermann , Alexandra Golby , Tina Kapur , William Wells

Robust and accurate 2D/3D registration, which aligns preoperative models with intraoperative images of the same anatomy, is crucial for successful interventional navigation. To mitigate the challenge of a limited field of view in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Yuxin Cui , Rui Song , Yibin Li , Max Q. -H. Meng , Zhe Min

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Establishing voxelwise semantic correspondence across distinct imaging modalities is a foundational yet formidable computer vision task. Current multi-modality registration techniques maximize hand-crafted inter-domain similarity functions,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Neel Dey , Jo Schlemper , Seyed Sadegh Mohseni Salehi , Bo Zhou , Guido Gerig , Michal Sofka

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Many applications in image-guided surgery and therapy require fast and reliable non-linear, multi-modal image registration. Recently proposed unsupervised deep learning-based registration methods have demonstrated superior performance…

Image and Video Processing · Electrical Eng. & Systems 2022-10-07 Gerard Snaauw , Michele Sasdelli , Gabriel Maicas , Stephan Lau , Johan Verjans , Mark Jenkinson , Gustavo Carneiro

Reliably and physically accurately transferring information between images through deformable image registration with large anatomical differences is an open challenge in medical image analysis. Most existing methods have two key…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Georgios Andreadis , Peter A. N. Bosman , Tanja Alderliesten

In this paper, we summarize the methods and experimental results we proposed for Task 2 in the learn2reg 2024 Challenge. This task focuses on unsupervised registration of anatomical structures in brain MRI images between different patients.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yuxi Zhang , Xiang Chen , Jiazheng Wang , Min Liu , Yaonan Wang , Dongdong Liu , Renjiu Hu , Hang Zhang

Image-based navigation is widely considered the next frontier of minimally invasive surgery. It is believed that image-based navigation will increase the access to reproducible, safe, and high-precision surgery as it may then be performed…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Mathias Unberath , Cong Gao , Yicheng Hu , Max Judish , Russell H Taylor , Mehran Armand , Robert Grupp

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch
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