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The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Deep learning models in the Earth Observation domain heavily rely on the availability of large-scale accurately labeled satellite imagery. However, obtaining and labeling satellite imagery is a resource-intensive endeavor. While generative…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Orkhan Baghirli , Hamid Askarov , Imran Ibrahimli , Ismat Bakhishov , Nabi Nabiyev

With the rapid development of artificial intelligence (AI), AI-assisted medical imaging analysis demonstrates remarkable performance in early lung cancer screening. However, the costly annotation process and privacy concerns limit the…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Yifan Jiang , Yannick Lemaréchal , Sophie Plante , Josée Bafaro , Jessica Abi-Rjeile , Philippe Joubert , Philippe Després , Venkata Manem

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Recent advances in Diffusion Probabilistic Models (DPMs) have set new standards in high-quality image synthesis. Yet, controlled generation remains challenging, particularly in sensitive areas such as medical imaging. Medical images feature…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sarah Cechnicka , Matthew Baugh , Weitong Zhang , Mischa Dombrowski , Zhe Li , Johannes C. Paetzold , Candice Roufosse , Bernhard Kainz

The segmentation and tracking of living cells play a vital role within the biomedical domain, particularly in cancer research, drug development, and developmental biology. These are usually tedious and time-consuming tasks that are…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rüveyda Yilmaz , Dennis Eschweiler , Johannes Stegmaier

Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Arnela Hadzic , Lea Bogensperger , Simon Johannes Joham , Martin Urschler

Denoising Diffusion Probabilistic Models (DDPMs) are powerful generative deep learning models that have been very successful at image generation, and, very recently, in path planning and control. In this paper, we investigate how to…

Robotics · Computer Science 2024-11-18 Michiel Nikken , Nicolò Botteghi , Wesley Roozing , Federico Califano

Constructing a highly accurate handwritten OCR system requires large amounts of representative training data, which is both time-consuming and expensive to collect. To mitigate the issue, we propose a denoising diffusion probabilistic model…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Haisong Ding , Bozhi Luan , Dongnan Gui , Kai Chen , Qiang Huo

Diffusion models have emerged as a popular family of deep generative models (DGMs). In the literature, it has been claimed that one class of diffusion models -- denoising diffusion probabilistic models (DDPMs) -- demonstrate superior image…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Rucha Deshpande , Muzaffer Özbey , Hua Li , Mark A. Anastasio , Frank J. Brooks

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

The success of Deep Learning applications critically depends on the quality and scale of the underlying training data. Generative adversarial networks (GANs) can generate arbitrary large datasets, but diversity and fidelity are limited,…

Denoising diffusion probabilistic models (DDPMs) have been proven capable of synthesizing high-quality images with remarkable diversity when trained on large amounts of data. Typical diffusion models and modern large-scale conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jingyuan Zhu , Huimin Ma , Jiansheng Chen , Jian Yuan

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson
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