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Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Optical Coherence Tomography Angiography (OCTA) has been increasingly used in the management of eye and systemic diseases in recent years. Manual or automatic analysis of blood vessel in 2D OCTA images (en face angiograms) is commonly used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-01 Shuai Yu , Jianyang Xie , Jinkui Hao , Yalin Zheng , Jiong Zhang , Yan Hu , Jiang Liu , Yitian Zhao

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree: the cerebral arteries, the bifurcations and the intracranial aneurysms. By building this model, our goal was to provide a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Coronary artery disease (CAD) remains the leading cause of death globally and invasive coronary angiography (ICA) is considered the gold standard of anatomical imaging evaluation when CAD is suspected. However, risk evaluation based on ICA…

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…

Computer Vision and Pattern Recognition · Computer Science 2022-11-04 Ramtin Gharleghi , Dona Adikari , Katy Ellenberger , Mark Webster , Chris Ellis , Arcot Sowmya , Sze-Yuan Ooi , Susann Beier

The determination of a coronary stenosis and its severity in current clinical workflow is typically accomplished manually via physician visual assessment (PVA) during invasive coronary angiography. While PVA has shown large inter-rater…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Benjamin Au , Uri Shaham , Sanket Dhruva , Georgios Bouras , Ecaterina Cristea , Alexandra Lansky MD , Andreas Coppi , Fred Warner , Shu-Xia Li , Harlan Krumholz

In patients with obstructive coronary artery disease, the functional significance of a coronary artery stenosis needs to be determined to guide treatment. This is typically established through fractional flow reserve (FFR) measurement,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Majd Zreik , Robbert W. van Hamersvelt , Nadieh Khalili , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

Coronary Heart Disease (CHD) is a leading cause of death in the modern world. The development of modern analytical tools for diagnostics and treatment of CHD is receiving substantial attention from the scientific community. Deep…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Maxim Popov , Temirgali Aimyshev , Eldar Ismailov , Ablay Bulegenov , Siamac Fazli

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Accurate extraction of coronary arteries from invasive coronary angiography (ICA) is important in clinical decision-making for the diagnosis and risk stratification of coronary artery disease (CAD). In this study, we develop a method using…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Yinghui Meng , Zhenglong Du , Chen Zhao , Minghao Dong , Drew Pienta , Zhihui Xu , Weihua Zhou

High-quality 3D reconstruction of pulmonary segments plays a crucial role in segmentectomy and surgical planning for the treatment of lung cancer. Due to the resolution requirement of the target reconstruction, conventional deep…

Graphics · Computer Science 2025-12-16 Kangxian Xie , Yufei Zhu , Kaiming Kuang , Li Zhang , Hongwei Bran Li , Mingchen Gao , Jiancheng Yang

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Deep learning-based whole-heart segmentation in coronary CT angiography (CCTA) allows the extraction of quantitative imaging measures for cardiovascular risk prediction. Automatic extraction of these measures in patients undergoing only…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Steffen Bruns , Jelmer M. Wolterink , Richard A. P. Takx , Robbert W. van Hamersvelt , Dominika Suchá , Max A. Viergever , Tim Leiner , Ivana Išgum

Coronary artery disease leading up to stenosis, the partial or total blocking of coronary arteries, is a severe condition that affects millions of patients each year. Automated identification and classification of stenosis severity from…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dinis L. Rodrigues , Miguel Nobre Menezes , Fausto J. Pinto , Arlindo L. Oliveira

Coronary computed tomography angiography (CCTA) provides 3D information on obstructive coronary artery disease, but cannot fully visualize high-resolution features within the vessel wall. Intravascular imaging, in contrast, can spatially…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Karim Kadry , Abhishek Karmakar , Andreas Schuh , Kersten Peterson , Michiel Schaap , David Marlevi , Charles Taylor , Elazer Edelman , Farhad Nezami

Accurate three-dimensional (3D) reconstruction of guidewire shapes is crucial for precise navigation in robot-assisted endovascular interventions. Conventional 2D Digital Subtraction Angiography (DSA) is limited by the absence of depth…

Robotics · Computer Science 2025-06-30 Tianliang Yao , Bingrui Li , Bo Lu , Zhiqiang Pei , Yixuan Yuan , Peng Qi

Personalised 3D vascular models are valuable for diagnosis, prognosis and treatment planning in patients with cardiovascular disease. Traditionally, such models have been constructed with explicit representations such as meshes and voxel…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Dieuwertje Alblas , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink