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MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…

In conventional 2D DCE-US, motion correction algorithms take advantage of accompanying side-by-side anatomical Bmode images that contain time-stable features. However, current commercial models of 3D DCE-US do not provide side-by-side Bmode…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Jia-Shu Chen , Maged Goubran Ph. D. , Gaeun Kim , Jurgen K. Willmann M. D. , Michael Zeineh M. D. , Ph. D. , Dimitre Hristov Ph. D. , Ahmed El Kaffas Ph. D

A biosignal is a signal that can be continuously measured from human bodies, such as respiratory sounds, heart activity (ECG), brain waves (EEG), etc, based on which, machine learning models have been developed with very promising…

Machine Learning · Computer Science 2022-01-26 Tong Xia , Jing Han , Cecilia Mascolo

Electrocardiography (ECG) is a low-cost, widely used modality for diagnosing electrical abnormalities like atrial fibrillation by capturing the heart's electrical activity. However, it cannot directly measure cardiac morphological…

Machine Learning · Computer Science 2026-03-10 Michelle Espranita Liman , Özgün Turgut , Alexander Müller , Eimo Martens , Daniel Rueckert , Philip Müller

Purpose: Ultrasound is the most commonly used medical imaging modality for diagnosis and screening in clinical practice. Due to its safety profile, noninvasive nature and portability, ultrasound is the primary imaging modality for fetal…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Sonit Singh , Gordon Stevenson , Brendan Mein , Alec Welsh , Arcot Sowmya

Computed ultrasound tomography in echo mode (CUTE) allows determining the spatial distribution of speed-of-sound (SoS) inside tissue using handheld pulse-echo ultrasound (US). This technique is based on measuring the changing phase of…

Medical Physics · Physics 2020-06-01 Patrick Stähli , Maju Kuriakose , Martin Frenz , Michael Jaeger

Echocardiography is widely used to clinical practice for diagnosis and treatment, e.g., on the common congenital heart defects. The traditional manual manipulation is error-prone due to the staff shortage, excess workload, and less…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Fuhai Chen , Rongrong Ji , Chengpeng Dai , Xuri Ge , Shengchuang Zhang , Xiaojing Ma , Yue Gao

Voltage-sensitive fluorescence imaging is widely used to image action potential waves in the heart. However, while the electrical waves trigger mechanical contraction, imaging needs to be performed with pharmacologically…

Medical Physics · Physics 2026-03-12 Shrey Chowdhary , Jan Lebert , Shai Dickman , Charles Gordon , Jan Christoph

Thanks to its capability of acquiring full-view frames at multiple kilohertz, ultrafast ultrasound imaging unlocked the analysis of rapidly changing physical phenomena in the human body, with pioneering applications such as ultrasensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Dimitris Perdios , Manuel Vonlanthen , Florian Martinez , Marcel Arditi , Jean-Philippe Thiran

Heart failure is a leading cause of mortality in the Western world. The mouse is a widely used model for a number of diseases, induced by genetic modification or surgical intervention. When performing experiments in mice, in vivo magnetic…

Medical Physics · Physics 2022-01-11 Guido Buonincontri

Wearable devices enable continuous, population-scale monitoring of physiological signals, such as photoplethysmography (PPG), creating new opportunities for data-driven clinical assessment. Time-series extrinsic regression (TSER) models…

Machine Learning · Computer Science 2026-01-16 Mesut Ceylan , Alexis Tabin , Patrick Langer , Elgar Fleisch , Filipe Barata

Owing to recent advances in thoracic electrical impedance tomography, a patient's hemodynamic function can be noninvasively and continuously estimated in real-time by surveilling a cardiac volume signal associated with stroke volume and…

Signal Processing · Electrical Eng. & Systems 2023-01-05 Chang Min Hyun , Tae Jun Jang , Jeongchan Nam , Hyeuknam Kwon , Kiwan Jeon , Kyunghun Lee

Ultrasound-based elasticity imaging is a non-invasive technique for estimating tissue stiffness fields from displacement fields obtained by comparing ultrasound signals before and after compression. While recent deep learning approaches…

Medical Physics · Physics 2026-01-22 Heekyu Kim , Hugon LEe , Minwoo Park , Seunghwa Ryu

Research ultrasound scanners such as the Verasonics Vantage often lack the advanced image processing algorithms used by clinical systems. Image quality is even lower in plane wave imaging - often used for shear wave elasticity imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Reed Chen , Courtney Trutna Paley , Wren Wightman , Lisa Hobson-Webb , Yohei Harada , Felix Jin , Ouwen Huang , Mark Palmeri , Kathryn Nightingale

We perform unsupervised analysis of image-derived shape and motion features extracted from 3822 cardiac 4D MRIs of the UK Biobank. First, with a feature extraction method previously published based on deep learning models, we extract from…

Computer Vision and Pattern Recognition · Computer Science 2019-02-18 Qiao Zheng , Hervé Delingette , Kenneth Fung , Steffen E. Petersen , Nicholas Ayache

Cardiac magnetic resonance imaging (MRI) is a pivotal tool for assessing cardiac function. Precise segmentation of cardiac structures is imperative for accurate cardiac functional evaluation. This paper introduces a semi-supervised model…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Hejun Huang , Zuguo Chen , Yi Huang , Guangqiang Luo , Chaoyang Chen , Youzhi Song

Ultrasound elastography is an emerging noninvasive imaging technique wherein pathological alterations can be visualized by revealing the mechanical properties of the tissue. Estimating tissue displacement in all directions is required to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Morteza Mirzaei , Amir Asif , Hassan Rivaz

In this paper, we present a novel Image Fusion Model (IFM) for ECG heart-beat classification to overcome the weaknesses of existing machine learning techniques that rely either on manual feature extraction or direct utilization of 1D raw…

Signal Processing · Electrical Eng. & Systems 2021-05-31 Zeeshan Ahmad , Anika Tabassum , Naimul Khan , Ling Guan

Fetal heart motion is an important diagnostic indicator for structural detection and functional assessment of congenital heart disease. We propose an approach towards integrating deep convolutional and recurrent architectures that utilize…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Arijit Patra , J. A. Noble

Motivation: CMR is the golden standard for cardiac diagnosis, and medical data annotation is time-consuming. Thus, screening techniques from unlabeled data can help streamline the cardiac diagnosis process. Goal: This work aims to enable…

Tissues and Organs · Quantitative Biology 2025-11-11 Yundi Zhang , Daniel Rueckert , Jiazhen Pan