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Quadratic Unconstrained Binary Optimization (QUBO) problems are NP-hard problems and many real-world problems can be formulated as QUBO. Currently there are no algorithms known that can solve arbitrary instances of NP-hard problems…

Quantum Physics · Physics 2023-12-20 Christian Münch , Fritz Schinkel , Sebastian Zielinski , Stefan Walter

We present PyQUBO, an open-source, Python library for constructing quadratic unconstrained binary optimizations (QUBOs) from the objective functions and the constraints of optimization problems. PyQUBO enables users to prepare QUBOs or…

Quantum Physics · Physics 2021-03-04 Mashiyat Zaman , Kotaro Tanahashi , Shu Tanaka

Even a minor boost in solving combinatorial optimization problems can greatly benefit multiple industries. Quantum computers, with their unique information processing capabilities, hold promise for delivering such enhancements. The…

Quantum Physics · Physics 2025-05-15 Gabriel Marin-Sanchez , David Amaro

This paper investigates the efficacy of quantum computing in two distinct machine learning tasks: feature selection for credit risk assessment and image classification for handwritten digit recognition. For the first task, we address the…

Quantum Physics · Physics 2025-11-05 JiaNing Long , Xuechen Liang

The D-Wave quantum annealing machine can quickly find the optimal solution for quadratic unconstrained binary optimization (QUBO). One of the applications where the use of quantum annealing is desired is in problems requiring rapid…

Quantum Physics · Physics 2024-12-11 Reo Shikanai , Masayuki Ohzeki , Kazuyuki Tanaka

Combinatorial optimization problems are ubiquitous in various disciplines and applications. Many heuristic algorithms have been devoted to solve these types of problems. In order to increase the efficiency for finding the optimal solutions,…

Quantum Physics · Physics 2023-11-10 Yu-Ting Kao , Jia-Le Liao , Hsiu-Chuan Hsu

We extend the family of problems that may be implemented on an adiabatic quantum optimizer (AQO). When a quadratic optimization problem has at least one set of discrete controls and the constraints are linear, we call this a quadratic…

Quantum Physics · Physics 2014-07-16 Rishabh Chandra , N. Tobias Jacobson , Jonathan E. Moussa , Steven H. Frankel , Sabre Kais

The field of Electronic Design Automation (EDA) is crucial for microelectronics, but the increasing complexity of Integrated Circuits (ICs) poses challenges for conventional EDA: Corresponding problems are often NP-hard and are therefore in…

Quantum Physics · Physics 2025-04-25 Matthias Jung , Sven O. Krumke , Christof Schroth , Elisabeth Lobe , Wolfgang Mauerer

Adiabatic quantum computers can solve difficult optimization problems (e.g., the quadratic unconstrained binary optimization problem), and they seem well suited to train machine learning models. In this paper, we describe an adiabatic…

This paper investigates Windfarm Layout Optimization (WFLO), where we formulate turbine placement considering wake effects as a Quadratic Unconstrained Binary Optimization (QUBO) problem. Wind energy plays a critical role in the transition…

Quantum Physics · Physics 2025-08-21 James Hancock , Matthew J. Craven , Craig McNeile , Davide Vadacchino

Quantum devices can be used to solve constrained combinatorial optimization (COPT) problems thanks to the use of penalization methods to embed the COPT problem's constraints in its objective to obtain a quadratic unconstrained binary…

Quantum Physics · Physics 2021-01-26 Rodolfo Quintero , David Bernal , Tamás Terlaky , Luis F. Zuluaga

We experimentally demonstrate that a digitized counterdiabatic quantum protocol reduces the number of topological defects created during a fast quench across a quantum phase transition. To show this, we perform quantum simulations of one-…

In more recent years, there has been increasing research interest in exploiting the use of application specific hardware for solving optimisation problems. Examples of solvers that use specialised hardware are IBM's Quantum System One and…

Neural and Evolutionary Computing · Computer Science 2022-11-14 Mayowa Ayodele

We propose and evaluate a quantum-inspired algorithm for solving Quadratic Unconstrained Binary Optimization (QUBO) problems, which are mathematically equivalent to finding ground states of Ising spin-glass Hamiltonians. The algorithm…

Artificial Intelligence · Computer Science 2025-10-24 Max B. Zhao , Fei Li

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

Binary optimisation tasks are ubiquitous in areas ranging from logistics to cryptography. The exponential complexity of such problems means that the performance of traditional computational methods decreases rapidly with increasing problem…

Quantum computing for machine learning attracts increasing attention and recent technological developments suggest that especially adiabatic quantum computing may soon be of practical interest. In this paper, we therefore consider this…

Machine Learning · Statistics 2017-06-20 Christian Bauckhage , Eduardo Brito , Kostadin Cvejoski , Cesar Ojeda , Rafet Sifa , Stefan Wrobel

Optimizing objective functions stands to benefit significantly from leveraging quantum computers, promising enhanced solution quality across various application domains in the future. However, harnessing the potential of quantum solvers…

Quantum Physics · Physics 2025-10-15 Deborah Volpe , Nils Quetschlich , Mariagrazia Graziano , Giovanna Turvani , Robert Wille

Codesign, an integral part of computer architecture referring to the information interaction in hardware-software stack, is able to boost the algorithm mapping and execution in the computer hardware. This well applies to the noisy…

The problem of selecting an appropriate number of features in supervised learning problems is investigated in this paper. Starting with common methods in machine learning, we treat the feature selection task as a quadratic unconstrained…

Quantum Physics · Physics 2023-06-21 Gerhard Hellstern , Vanessa Dehn , Martin Zaefferer
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