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A platform trial is an innovative clinical trial design that uses a master protocol to evaluate multiple treatments, where patients are often assigned to different subsets of treatment arms based on individual characteristics, enrollment…

We study transfer learning for estimation in latent variable network models. In our setting, the conditional edge probability matrices given the latent variables are represented by $P$ for the source and $Q$ for the target. We wish to…

Machine Learning · Computer Science 2024-06-07 Akhil Jalan , Arya Mazumdar , Soumendu Sundar Mukherjee , Purnamrita Sarkar

In randomized controlled trials without interference, regression adjustment is widely used to enhance the efficiency of treatment effect estimation. This paper extends this efficiency principle to settings with network interference, where a…

Methodology · Statistics 2025-02-18 Xinyuan Fan , Chenlei Leng , Weichi Wu

Ensuring generalization to unseen environments remains a challenge. Domain shift can lead to substantially degraded performance unless shifts are well-exercised within the available training environments. We introduce a simple robust…

Machine Learning · Computer Science 2021-10-20 Yilun Xu , Tommi Jaakkola

Transfer learning has become an essential technique for utilizing information from source datasets to improve the performance of the target task. However, in the context of high-dimensional data, heterogeneity arises due to heteroscedastic…

Methodology · Statistics 2024-06-26 Xiaohui Yuan , Shujie Ren

We study variable selection (also called support recovery) in high-dimensional sparse linear regression when one has external information on which variables are likely to be associated with the response. Consistent recovery is only possible…

Statistics Theory · Mathematics 2026-02-16 Paul Rognon-Vael , David Rossell , Piotr Zwiernik

In most applications of utilizing neural networks for mathematical optimization, a dedicated model is trained for each specific optimization objective. However, in many scenarios, several distinct yet correlated objectives or tasks often…

Machine Learning · Computer Science 2024-04-15 Wei Cui , Wei Yu

Estimating heterogeneous treatment effects is an important problem across many domains. In order to accurately estimate such treatment effects, one typically relies on data from observational studies or randomized experiments. Currently,…

Machine Learning · Statistics 2022-02-28 Tobias Hatt , Jeroen Berrevoets , Alicia Curth , Stefan Feuerriegel , Mihaela van der Schaar

We propose a method for transfer learning in nonparametric regression using a random forest (RF) with distance covariance-based feature weights, assuming the unknown source and target regression functions are sparsely different. Our method…

Machine Learning · Statistics 2026-03-17 Chenze Li , Subhadeep Paul

Transfer learning is an emerging and popular paradigm for utilizing existing knowledge from previous learning tasks to improve the performance of new ones. Despite its numerous empirical successes, theoretical analysis for transfer learning…

Machine Learning · Computer Science 2023-01-30 Haoyang Cao , Haotian Gu , Xin Guo , Mathieu Rosenbaum

This paper studies inference in randomized controlled trials with covariate-adaptive randomization when there are multiple treatments. More specifically, we study inference about the average effect of one or more treatments relative to…

Econometrics · Economics 2019-01-21 Federico A. Bugni , Ivan A. Canay , Azeem M. Shaikh

External controls from historical trials or observational data can augment randomized controlled trials when large-scale randomization is impractical or unethical, such as in drug evaluation for rare diseases. However, non-randomized…

Methodology · Statistics 2025-05-08 Ke Zhu , Shu Yang , Xiaofei Wang

We take steps towards causally interpretable meta-analysis by describing methods for transporting causal inferences from a collection of randomized trials to a new target population, one-trial-at-a-time and pooling all trials. We discuss…

Information from related source studies can often enhance the findings of a target study. However, the distribution shift between target and source studies can severely impact the efficiency of knowledge transfer. In the high-dimensional…

Methodology · Statistics 2025-11-26 Ruiqi Bai , Yijiao Zhang , Hanbo Yang , Zhongyi Zhu

In this paper, we study transfer learning for high-dimensional factor-augmented sparse linear models, motivated by applications in economics and finance where strongly correlated predictors and latent factor structures pose major challenges…

Methodology · Statistics 2026-03-23 Bo Fu , Dandan Jiang

In oncology the efficacy of novel therapeutics often differs across patient subgroups, and these variations are difficult to predict during the initial phases of the drug development process. The relation between the power of randomized…

Methodology · Statistics 2025-06-05 Boyu Ren , Federico Ferrari , Sandra Fortini , Steffen Ventz , Lorenzo Trippa

In 2023, the U.S. Food and Drug Administration issued guidance for adjustment of covariates in randomized clinical trials, emphasizing its role in enhancing precision and power through prognostic baseline variables. Despite its potential,…

Methodology · Statistics 2026-05-28 Kelly Van Lancker , Iván Díaz , Stijn Vansteelandt

Transfer learning has become a central paradigm in modern machine learning, yet it suffers from the long-standing problem of negative transfer, where leveraging source representations can harm rather than help performance on the target…

Machine Learning · Computer Science 2026-04-28 Yichen Xu , Ryumei Nakada , Linjun Zhang , Lexin Li

Methods of transfer learning try to combine knowledge from several related tasks (or domains) to improve performance on a test task. Inspired by causal methodology, we relax the usual covariate shift assumption and assume that it holds true…

Machine Learning · Statistics 2018-09-25 Mateo Rojas-Carulla , Bernhard Schölkopf , Richard Turner , Jonas Peters

There are many time series in the literature with high dimension yet limited sample sizes, such as macroeconomic variables, and it is almost impossible to obtain efficient estimation and accurate prediction by using the corresponding…

Methodology · Statistics 2025-10-30 Yuchang Lin , Qianqian Zhu , Guodong Li
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