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Explainable artificial intelligence (XAI) methods have been proposed to interpret model decisions in classification and, more recently, in semantic segmentation. However, instance-level XAI for semantic segmentation, namely explanations…

Lesion segmentation is the first step in most automatic melanoma recognition systems. Deficiencies and difficulties in dermoscopic images such as color inconstancy, hair occlusion, dark corners and color charts make lesion segmentation an…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Mostafa Jahanifar , Neda Zamani Tajeddin , Babak Mohammadzadeh Asl , Ali Gooya

Deep neural networks (DNNs) are being increasingly used to make predictions from functional magnetic resonance imaging (fMRI) data. However, they are widely seen as uninterpretable "black boxes", as it can be difficult to discover what…

Machine Learning · Computer Science 2020-12-18 Patrick McClure , Dustin Moraczewski , Ka Chun Lam , Adam Thomas , Francisco Pereira

Automating Multiple Sclerosis (MS) lesion segmentation would be of great benefit in initial diagnosis as well as monitoring disease progression. Deep learning based segmentation models perform well in many domains, but the state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Liviu Badea , Maria Popa

Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tianyi Ren , Juampablo Heras Rivera , Hitender Oswal , Yutong Pan , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Saliency maps have become a widely used method to make deep learning models more interpretable by providing post-hoc explanations of classifiers through identification of the most pertinent areas of the input medical image. They are…

The detection of new multiple sclerosis (MS) lesions is an important marker of the evolution of the disease. The applicability of learning-based methods could automate this task efficiently. However, the lack of annotated longitudinal data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Reda Abdellah Kamraoui , Boris Mansencal , José V Manjon , Pierrick Coupé

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

Multi-parametric magnetic resonance imaging (mpMRI) has a growing role in detecting prostate cancer lesions. Thus, it is pertinent that medical professionals who interpret these scans reduce the risk of human error by using computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Haoli Yin , Nithin Buduma

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Saliency maps are a popular approach for explaining classifications of (convolutional) neural networks. However, it remains an open question as to how best to evaluate salience maps, with three families of evaluation methods commonly being…

Human-Computer Interaction · Computer Science 2025-04-25 Felix Kares , Timo Speith , Hanwei Zhang , Markus Langer

A particular class of Explainable AI (XAI) methods provide saliency maps to highlight part of the image a Convolutional Neural Network (CNN) model looks at to classify the image as a way to explain its working. These methods provide an…

Machine Learning · Computer Science 2021-06-25 Sam Zabdiel Sunder Samuel , Vidhya Kamakshi , Namrata Lodhi , Narayanan C Krishnan

In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

Recently, many methods to interpret and visualize deep neural network predictions have been proposed and significant progress has been made. However, a more class-discriminative and visually pleasing explanation is required. Thus, this…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Dasom Seo , Kanghan Oh , Il-Seok Oh

The diagnosis of prostate cancer faces a problem with overdiagnosis that leads to damaging side effects due to unnecessary treatment. Research has shown that the use of multi-parametric magnetic resonance images to conduct biopsies can…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Pedro C. Neto

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Convolutional neural networks (CNNs) offer great machine learning performance over a range of applications, but their operation is hard to interpret, even for experts. Various explanation algorithms have been proposed to address this issue,…

Human-Computer Interaction · Computer Science 2020-02-04 Ahmed Alqaraawi , Martin Schuessler , Philipp Weiß , Enrico Costanza , Nadia Berthouze

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Nils Gessert , Marcel Bengs , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Sven Schippling , Alexander Schlaefer

This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan
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