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In high energy density physics (HEDP) and inertial confinement fusion (ICF), predictive modeling is complicated by uncertainty in parameters that characterize various aspects of the modeled system, such as those characterizing material…

Accurately predicting the elastic properties of crystalline solids is vital for computational materials science. However, traditional atomistic scale ab initio approaches are computationally intensive, especially for studying complex…

Disordered Systems and Neural Networks · Physics 2023-11-13 Teerachote Pakornchote , Annop Ektarawong , Thiparat Chotibut

Biological data including gene expression data are generally high-dimensional and require efficient, generalizable, and scalable machine-learning methods to discover their complex nonlinear patterns. The recent advances in machine learning…

Machine Learning · Computer Science 2020-12-21 Dinesh Singh , Héctor Climente-González , Mathis Petrovich , Eiryo Kawakami , Makoto Yamada

Predicting the biological function of molecules, be it proteins or drug-like compounds, from their atomic structure is an important and long-standing problem. Function is dictated by structure, since it is by spatial interactions that…

We present a physics-embedded Bayesian neural network (PE-BNN) framework that integrates fission product yields (FPYs) with prior nuclear physics knowledge to predict energy-dependent FPY data with fine structure. By incorporating an…

Deep neural networks (DNN) have shown remarkable success in the classification of physiological signals. In this study we propose a method for examining to what extent does a DNN's performance rely on rediscovering existing features of the…

Machine Learning · Statistics 2020-08-26 Tom Beer , Bar Eini-Porat , Sebastian Goodfellow , Danny Eytan , Uri Shalit

Due to the highly complex chemical structure of biomolecules, the extensive understanding of the electronic information for proteomics can be challenging. Here, we constructed a charge transfer database at residue level derived from…

Chemical Physics · Physics 2019-04-05 Fang Liu , Hongwei Wang , Dongju Zhang , Likai Du

Deep neural networks (DNNs) are a type of artificial intelligence models that are inspired by the structure and function of the human brain, designed to process and learn from large amounts of data, making them particularly well-suited for…

Hardware Architecture · Computer Science 2024-07-18 Alireza Senobari , Jafar Vafaei , Omid Akbari , Christian Hochberger , Muhammad Shafique

We introduce scalable machine learning models to accurately predict two key quantum transport properties, the transmission coefficient T(E) and average local density of states (Average-LDOS) in two-dimensional (2D) hexagonal materials with…

Mesoscale and Nanoscale Physics · Physics 2026-02-17 Seyed Mahdi Mastoor , Amirhossein Ahmadkhan Kordbacheh

The significant imbalance between power generation and load caused by severe disturbance may make the power system unable to maintain a steady frequency. If the post-disturbance dynamic frequency features can be predicted and emergency…

Signal Processing · Electrical Eng. & Systems 2019-09-23 Jintian Lin , Yichao Zhang , Xiaoru Wang , Qingyue Chen

Understanding how protein mutations affect protein-nucleic acid binding is critical for unraveling disease mechanisms and advancing therapies. Current experimental approaches are laborious, and computational methods remain limited in…

Quantitative Methods · Quantitative Biology 2025-05-30 Xiang Liu , Junjie Wee , Guo-Wei Wei

Deep learning methods have demonstrated outstanding performances on classification and regression tasks on homogeneous data types (e.g., image, audio, and text data). However, tabular data still pose a challenge, with classic machine…

Machine Learning · Computer Science 2023-11-15 Antonio Briola , Yuanrong Wang , Silvia Bartolucci , Tomaso Aste

Energy-based models (EBMs) are a simple yet powerful framework for generative modeling. They are based on a trainable energy function which defines an associated Gibbs measure, and they can be trained and sampled from via well-established…

Machine Learning · Computer Science 2021-05-06 Carles Domingo-Enrich , Alberto Bietti , Eric Vanden-Eijnden , Joan Bruna

Topological materials exhibit unique electronic structures that underpin both fundamental quantum phenomena and next-generation technologies, yet their discovery remains constrained by the high computational cost of first-principles…

Materials Science · Physics 2025-12-16 Xinyu Xu , Rajibul Islam , Ghulam Hussain , Yangming Huang , Xiaoguang Li , Pavlo O. Dral , Arif Ullah , Ming Yang

Proteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics and transport is one of most challenging tasks in biological science. In the present work, persistent homology is,…

Biomolecules · Quantitative Biology 2014-12-10 Kelin Xia , Guo-Wei Wei

Neural network potentials (NNPs) enable large-scale molecular dynamics (MD) simulations of systems containing >10,000 atoms with the accuracy comparable to ab initio methods and play a crucial role in material studies. Although NNPs are…

Binding energy is a fundamental thermodynamic property that governs molecular interactions, playing a crucial role in fields such as healthcare and the natural sciences. It is particularly relevant in drug development, vaccine design, and…

Quantum Physics · Physics 2025-08-06 Erico Souza Teixeira , Lucas Barros Fernandes , Yara Rodrigues Inácio

In this work we introduce a differentiable version of the Compositional Pattern Producing Network, called the DPPN. Unlike a standard CPPN, the topology of a DPPN is evolved but the weights are learned. A Lamarckian algorithm, that combines…

Neural and Evolutionary Computing · Computer Science 2016-06-09 Chrisantha Fernando , Dylan Banarse , Malcolm Reynolds , Frederic Besse , David Pfau , Max Jaderberg , Marc Lanctot , Daan Wierstra

The inner representation of deep neural networks (DNNs) is indecipherable, which makes it difficult to tune DNN models, control their training process, and interpret their outputs. In this paper, we propose a novel approach to investigate…

Machine Learning · Computer Science 2021-06-08 Satoru Watanabe , Hayato Yamana

Many DNN-enabled vision applications constantly operate under severe energy constraints such as unmanned aerial vehicles, Augmented Reality headsets, and smartphones. Designing DNNs that can meet a stringent energy budget is becoming…

Machine Learning · Computer Science 2019-04-09 Haichuan Yang , Yuhao Zhu , Ji Liu
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