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An important aspect of modeling spatially-referenced data is appropriately specifying the covariance function of the random field. A practitioner working with spatial data is presented a number of choices regarding the structure of the…

Methodology · Statistics 2015-11-06 Zachary D. Weller , Jennifer A. Hoeting

We propose a series-based nonparametric specification test for a regression function when data are spatially dependent, the `space' being of a general economic or social nature. Dependence can be parametric, parametric with increasing…

Econometrics · Economics 2022-08-30 Abhimanyu Gupta , Xi Qu

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…

Applications · Statistics 2023-05-16 Arhit Chakrabarti , Yang Ni , Bani K. Mallick

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Reliable inference for spatial regression remains challenging because it requires the correct specification of the spatial dependence structure, the mean trend, and the error distribution. Existing parametric testing methods rely on…

Methodology · Statistics 2026-05-12 Kanghyun Wi , Hyoeun Kim , Tomáš Mrkvička , Jorge Mateu , Jaewoo Park

We propose a flexible and robust nonparametric framework for testing spatial dependence in two- and three-dimensional random fields. Our approach involves converting spatial data into one-dimensional time series using space-filling Hilbert…

Methodology · Statistics 2025-10-20 Christian H. Weiß , Philipp Adämmer

In process monitoring, it is common for measurements to be taken regularly or randomly from different spatial locations in two or three dimensions. While there are nonparametric methods for process monitoring with such spatial data to…

Methodology · Statistics 2025-05-06 Philipp Adämmer , Philipp Wittenberg , Christian H. Weiß , Murat Caner Testik

Detecting spatial patterns is fundamental to scientific discovery, yet current methods lack statistical consensus and face computational barriers when applied to large-scale spatial omics datasets. We unify major approaches through a single…

Applications · Statistics 2026-02-04 Jiayu Su , Jun Hou Fung , Haoyu Wang , Dian Yang , David A. Knowles , Raul Rabadan

Understanding the complex nature of spatial information is crucial for problem solving in social and environmental sciences. This study investigates how the underlying patterns of spatial data can significantly influence the outcomes of…

Physics and Society · Physics 2024-09-17 Peng Luo , Yongze Song , Wenwen Li , Liqiu Meng

Spatial association measures for univariate static spatial data are widely used. When the data is in the form of a collection of spatial vectors with the same temporal domain of interest, we construct a measure of similarity between the…

Methodology · Statistics 2023-09-26 Divya Kappara , Arup Bose , Madhuchhanda Bhattacharjee

Spatial association and heterogeneity are two critical areas in the research about spatial analysis, geography, statistics and so on. Though large amounts of outstanding methods has been proposed and studied, there are few of them tend to…

Econometrics · Economics 2018-03-26 Zihao Yuan

An important step of modeling spatially-referenced data is appropriately specifying the second order properties of the random field. A scientist developing a model for spatial data has a number of options regarding the nature of the…

Computation · Statistics 2015-11-17 Zachary D. Weller

Standard geostatistical models assume stationarity and rely on a variogram model to account for the spatial dependence in the observed data. In some instances, this assumption that the spatial dependence structure is constant throughout the…

Methodology · Statistics 2022-12-16 Dave Higdon , Jenise Swall , John Kern

In this paper, a robust non-parametric measure of statistical dependence, or correlation, between two random variables is presented. The proposed coefficient is a permutation-like statistic that quantifies how much the observed sample S_n :…

Methodology · Statistics 2020-07-27 Rami Mahdi

We propose a nonparametric test of spatial independence for data observed on irregular, non-lattice point clouds $\mathcal{V}_{n}\subset\mathbb{R}^{2}$. For each location $v\in\mathcal{V}_{n}$, we encode the local spatial configuration…

We consider an analysis of variance type problem, where the sample observations are random elements in an infinite dimensional space. This scenario covers the case, where the observations are random functions. For such a problem, we propose…

Methodology · Statistics 2022-07-26 Joydeep Chowdhury , Probal Chaudhuri

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

A crucial assumption to reduce computational complexity in spatial-temporal data analysis is separability, which factors the covariance structure into a purely spatial and a purely temporal component. In this paper, we develop statistical…

Statistics Theory · Mathematics 2026-03-30 Lujia Bai , Holger Dette , Zihao Yuan

We propose statistical procedures for detecting changes in the mean of spatial random fields observed on regular grids. The proposed framework provides a general approach to change detection in spatial processes. Extending a block-based…

Methodology · Statistics 2025-12-15 Sheila T. Görz , Roland Fried
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