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Following the milestones in large language models (LLMs) and multimodal models, we have seen a surge in applying LLMs to biochemical tasks. Leveraging graph features and molecular text representations, LLMs can tackle various tasks, such as…

Machine Learning · Computer Science 2025-02-14 Chengxin Hu , Hao Li , Yihe Yuan , Jing Li , Ivor Tsang

In order for clinicians to manage disease progression and make effective decisions about drug dosage, treatment regimens or scheduling follow up appointments, it is necessary to be able to identify both short and long-term trends in…

Quantitative Methods · Quantitative Biology 2016-12-06 Norman Poh , Simon Bull , Santosh Tirunagari , Nicholas Cole , Simon de Lusignan

Large language models (LLMs) can simulate clinical reasoning based on natural language prompts, but their utility in ophthalmology is largely unexplored. This study evaluated GPT-4's ability to interpret structured textual descriptions of…

Computation and Language · Computer Science 2025-07-03 Cindy Lie Tabuse , David Restepo , Carolina Gracitelli , Fernando Korn Malerbi , Caio Regatieri , Luis Filipe Nakayama

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…

Machine Learning · Computer Science 2023-10-18 Tomas M. Bosschieter , Zifei Xu , Hui Lan , Benjamin J. Lengerich , Harsha Nori , Ian Painter , Vivienne Souter , Rich Caruana

Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Electroencephalography (EEG) signals provide critical insights for applications in disease diagnosis and healthcare. However, the scarcity of labeled EEG data poses a significant challenge. Foundation models offer a promising solution by…

Machine Learning · Computer Science 2025-02-25 Limin Wang , Toyotaro Suzumura , Hiroki Kanezashi

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

Large language models (LLMs) excel at reasoning but struggle with knowledge-intensive questions due to limited context and parametric knowledge. However, existing methods that rely on finetuned LLMs or GNN retrievers are limited by…

Artificial Intelligence · Computer Science 2025-11-07 Yuanning Cui , Zequn Sun , Wei Hu , Zhangjie Fu

Foundation models, large machine learning models trained on broad, multimodal datasets, have been gaining increasing attention in scientific applications due to their strong performance on diverse downstream tasks. Large Language Models…

High Energy Physics - Phenomenology · Physics 2025-10-07 Manuel Morales-Alvarado

Background: Machine learning (ML) enhances gait analysis but often lacks the level of interpretability desired for clinical adoption. Large Language Models (LLMs) may offer explanatory capabilities and confidence-aware outputs when applied…

Machine Learning · Computer Science 2026-03-17 Carlo Dindorf , Jonas Dully , Rebecca Keilhauer , Michael Lorenz , Michael Fröhlich

Background and Objective: To address the inability of single-model architectures to perform simultaneous analysis of complex glomerular ultrastructures, we developed Glo-UMF, a unified multi-model framework integrating segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Zhentai Zhang , Danyi Weng , Guibin Zhang , Xiang Chen , Kaixing Long , Jian Geng , Yanmeng Lu , Lei Zhang , Zhitao Zhou , Lei Cao

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Large language models (LLMs) have demonstrated unprecedented emergent capabilities, including content generation, translation, and simulation of human behavior. Field experiments, on the other hand, are widely employed in social studies to…

Computers and Society · Computer Science 2025-05-22 Yaoyu Chen , Yuheng Hu , Yingda Lu

Latent representation alignment has become a foundational technique for constructing multimodal large language models (MLLM) by mapping embeddings from different modalities into a shared space, often aligned with the embedding space of…

Machine Learning · Computer Science 2025-03-06 Dong Shu , Bingbing Duan , Kai Guo , Kaixiong Zhou , Jiliang Tang , Mengnan Du

Machine learning (ML) has the potential to become an essential tool in supporting clinical decision-making processes, offering enhanced diagnostic capabilities and personalized treatment plans. However, outsourcing medical records to train…

This study aims to simulate real-world clinical scenarios to systematically evaluate the ability of Large Language Models (LLMs) to extract core medical information from patient chief complaints laden with noise and redundancy, and to…

Artificial Intelligence · Computer Science 2025-12-15 Yuan Shen , Xiaojun Wu , Linghua Yu

Most pregnancies and births result in a good outcome, but complications are not uncommon and when they do occur, they can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve…

Multimodal Large Language Models (MLLMs) have recently demonstrated strong performance on a wide range of vision-language tasks, raising interest in their potential use for biometric applications. In this paper, we conduct a systematic…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Hatef Otroshi Shahreza , Anjith George , Sébastien Marcel

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong