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Understanding the biological and behavioral heterogeneity underlying psychiatric disorders is critical for advancing precision diagnosis, treatment, and prevention. This paper addresses the scientific question of how multimodal data,…

Methodology · Statistics 2025-11-10 Yinjun Zhao , Yuanjia Wang , Ying LIu

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Emotion recognition has a pivotal role in affective computing and in human-computer interaction. The current technological developments lead to increased possibilities of collecting data about the emotional state of a person. In general,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Andreea Birhala , Catalin Nicolae Ristea , Anamaria Radoi , Liviu Cristian Dutu

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

Mental health disorders remain among the leading cause of disability worldwide, yet conditions such as depression, anxiety, and Post-Traumatic Stress Disorder (PTSD) are frequently underdiagnosed or misdiagnosed due to subjective…

Computation and Language · Computer Science 2025-10-17 Jianfeng Zhu , Julina Maharjan , Xinyu Li , Karin G. Coifman , Ruoming Jin

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

Machine Learning · Computer Science 2026-04-14 Farica Zhuang , Shu Yang , Dinara Aliyeva , Zixuan Wen , Duy Duong-Tran , Christos Davatzikos , Tianlong Chen , Song Wang , Li Shen

Depression is a severe mental disorder, and reliable identification plays a critical role in early intervention and treatment. Multimodal depression detection aims to improve diagnostic performance by jointly modeling complementary…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chongxiao Wang , Junjie Liang , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Audio-visual information fusion enables a performance improvement in speech recognition performed in complex acoustic scenarios, e.g., noisy environments. It is required to explore an effective audio-visual fusion strategy for audiovisual…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-07 Liangfa Wei , Jie Zhang , Junfeng Hou , Lirong Dai

Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Guoxin Wang , Xuyang Cao , Shan An , Fengmei Fan , Chao Zhang , Jinsong Wang , Feng Yu , Zhiren Wang

In this paper, we propose a novel framework for recognizing both discrete and dimensional emotions. In our framework, deep features extracted from foundation models are used as robust acoustic and visual representations of raw video. Three…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-18 Haotian Wang , Yuxuan Xi , Hang Chen , Jun Du , Yan Song , Qing Wang , Hengshun Zhou , Chenxi Wang , Jiefeng Ma , Pengfei Hu , Ya Jiang , Shi Cheng , Jie Zhang , Yuzhe Weng

With the rapid growth in deepfake video content, we require improved and generalizable methods to detect them. Most existing detection methods either use uni-modal cues or rely on supervised training to capture the dissonance between the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Trevine Oorloff , Surya Koppisetti , Nicolò Bonettini , Divyaraj Solanki , Ben Colman , Yaser Yacoob , Ali Shahriyari , Gaurav Bharaj

Depression is a severe global mental health issue that impairs daily functioning and overall quality of life. Although recent audio-visual approaches have improved automatic depression detection, methods that ignore emotional cues often…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Chenglizhao Chen , Boze Li , Mengke Song , Dehao Feng , Xinyu Liu , Shanchen Pang , Jufeng Yang , Hui Yu

Humans possess a remarkable ability to integrate auditory and visual information, enabling a deeper understanding of the surrounding environment. This early fusion of audio and visual cues, demonstrated through cognitive psychology and…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Shentong Mo , Pedro Morgado

Depression and post traumatic stress disorder (PTSD) often co-occur with connected symptoms, complicating automated assessment, which is often binary and disorder specific. Clinically useful diagnosis needs severity aware cross disorder…

Computation and Language · Computer Science 2025-10-24 Filippo Cenacchi , Deborah Richards , Longbing Cao

Autonomous driving technology has advanced significantly, yet detecting driving anomalies remains a major challenge due to the long-tailed distribution of driving events. Existing methods primarily rely on single-modal road condition video…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Long Zhouxiang , Ovanes Petrosian

The increasing prevalence of mental health disorders, such as depression, anxiety, and bipolar disorder, calls for immediate need in developing tools for early detection and intervention. Social media platforms, like Reddit, represent a…

Machine Learning · Computer Science 2025-03-12 Qasim Bin Saeed , Ijaz Ahmed

A significant number of people are suffering from cognitive impairment all over the world. Early detection of cognitive impairment is of great importance to both patients and caregivers. However, existing approaches have their shortages,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-10 Zixiang Fei , Erfu Yang , Leijian Yu , Xia Li , Huiyu Zhou , Wenju Zhou

Automated mental health prediction using textual data has shown promising results with deep learning and large language models. However, deploying these models in high-stakes real-world settings remains challenging, as existing approaches…

Computation and Language · Computer Science 2026-05-07 Yucheng Ruan , Ling Huang , Qika Lin , Kai He , Mengling Feng
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