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Protein inverse folding, the design of an amino acid sequence based on a target protein structure, is a fundamental problem of computational protein engineering. Existing methods either generate sequences without leveraging external…

Quantitative Methods · Quantitative Biology 2026-03-10 Jin Han , Tianfan Fu , Wu-Jun Li

Benchmarks for coding agents increasingly measure source-level software repair, and cybersecurity benchmarks increasingly measure broad capture-the-flag performance. Classical binary reverse engineering remains less precisely specified:…

Software Engineering · Computer Science 2026-05-12 Isaac David , Arthur Gervais

Physics-informed neural networks (PINNs) provide a promising framework for solving inverse problems governed by partial differential equations (PDEs) by integrating observational data and physical constraints in a unified optimization…

Machine Learning · Computer Science 2026-04-07 Yongsheng Chen , Yong Chen , Wei Guo , Xinghui Zhong

Existing prompt-optimization techniques rely on local signals to update behavior, often neglecting broader and recurring patterns across tasks, leading to poor generalization; they further rely on full-prompt rewrites or unstructured…

Software Engineering · Computer Science 2026-03-24 Balaji Dinesh Gangireddi , Aniketh Garikaparthi , Manasi Patwardhan , Arman Cohan

This study addresses the challenge of reverse engineering binaries from unknown instruction set architectures, a complex task with potential implications for software maintenance and cyber-security. We focus on the tasks of detecting…

Cryptography and Security · Computer Science 2024-01-17 Håvard Pettersen , Donn Morrison

Byte-Pair Encoding (BPE) is a widely used method for subword tokenization, with origins in grammar-based text compression. It is employed in a variety of language processing tasks such as machine translation or large language model (LLM)…

Data Structures and Algorithms · Computer Science 2024-11-14 László Kozma , Johannes Voderholzer

Quantized neural networks employ reduced precision representations for both weights and activations. This quantization process significantly reduces the memory requirements and computational complexity of the network. Binary Neural Networks…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Edwin Vargas , Claudia Correa , Carlos Hinojosa , Henry Arguello

Tackling binary program analysis problems has traditionally implied manually defining rules and heuristics, a tedious and time-consuming task for human analysts. In order to improve automation and scalability, we propose an alternative…

Cryptography and Security · Computer Science 2021-05-25 Shushan Arakelyan , Sima Arasteh , Christophe Hauser , Erik Kline , Aram Galstyan

Model monitoring is a critical component of the machine learning lifecycle, safeguarding against undetected drops in the model's performance after deployment. Traditionally, performance monitoring has required access to ground truth labels,…

Machine Learning · Computer Science 2026-03-10 Juhani Kivimäki , Jakub Białek , Wojtek Kuberski , Jukka K. Nurminen

Byte-pair encoding (BPE) is a ubiquitous algorithm in the subword tokenization process of language models as it provides multiple benefits. However, this process is solely based on pre-training data statistics, making it hard for the…

Computation and Language · Computer Science 2021-09-27 Gustavo Aguilar , Bryan McCann , Tong Niu , Nazneen Rajani , Nitish Keskar , Thamar Solorio

Artificial neural networks (ANNs) trained using backpropagation are powerful learning architectures that have achieved state-of-the-art performance in various benchmarks. Significant effort has been devoted to developing custom silicon…

Neural and Evolutionary Computing · Computer Science 2017-08-17 Hesham Mostafa , Bruno Pedroni , Sadique Sheik , Gert Cauwenberghs

Binarization is an extreme network compression approach that provides large computational speedups along with energy and memory savings, albeit at significant accuracy costs. We investigate the question of where to binarize inputs at…

Computer Vision and Pattern Recognition · Computer Science 2018-04-12 Ameya Prabhu , Vishal Batchu , Rohit Gajawada , Sri Aurobindo Munagala , Anoop Namboodiri

In software reverse engineering, decompilation is the process of recovering source code from binary files. Decompilers are used when it is necessary to understand or analyze software for which the source code is not available. Although…

Software Engineering · Computer Science 2021-02-25 Javier Escalada , Ted Scully , Francisco Ortin

Fair data pre-processing is a widely used strategy for mitigating bias in machine learning. A promising line of research focuses on calibrating datasets to satisfy a designed fairness policy so that sensitive attributes influence outcomes…

Databases · Computer Science 2026-03-30 Ying Zheng , Yangfan Jiang , Kian-Lee Tan

Binary analysis is an important capability required for many security and software engineering applications. Consequently, there are many binary analysis techniques and tools with varied capabilities. However, testing these tools requires a…

Software Engineering · Computer Science 2023-01-09 Vidush Singhal , Akul Abhilash Pillai , Charitha Saumya , Milind Kulkarni , Aravind Machiry

In many science and engineering settings, system dynamics are characterized by governing PDEs, and a major challenge is to solve inverse problems (IPs) where unknown PDE parameters are inferred based on observational data gathered under…

Machine Learning · Computer Science 2025-03-11 Apivich Hemachandra , Gregory Kang Ruey Lau , See-Kiong Ng , Bryan Kian Hsiang Low

Finite element method (FEM) is one of the most important numerical methods in modern engineering design and analysis. Since traditional serial FEM is difficult to solve large FE problems efficiently and accurately, high-performance parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-06-01 Meng Wu , Can Yang , Taoran Xiang , Daning Cheng

Query reverse engineering (QRE) aims to synthesize a SQL query to connect a given database and result instance. A recent variation of QRE is where an additional input, an opaque executable containing a ground-truth query, is provided, and…

Databases · Computer Science 2025-04-16 Ahana Pradhan , Jayant Haritsa

The boundary element method (BEM) provides an efficient numerical framework for solving multiple scattering problems in unbounded homogeneous domains, since it reduces the discretization to the domain boundaries, thereby condensing the…

Machine Learning · Computer Science 2025-12-03 Rémi Marsal , Stéphanie Chaillat

As emerging attacks increasingly target Industrial Control Systems (ICS), the security of Programmable Logic Controllers (PLCs) has become a critical concern. Binary Code Analysis (BCA), which enables analysts to understand compiled…

Software Engineering · Computer Science 2026-05-21 Ang Jia , Yaxin Duan , He Jiang , Zhenzhou Tian , Zhilei Ren , Xiaochen Li
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