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In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

Industrial X-ray cone-beam CT (XCT) scanners are widely used for scientific imaging and non-destructive characterization. Industrial CBCT scanners use large detectors containing millions of pixels and the subsequent 3D reconstructions can…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Aniket Pramanik , Singanallur V. Venkatakrishnan , Obaidullah Rahman , Amirkoushyar Ziabari

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti

Inspired by the success of deep learning applications on restoration of low-dose and sparse CT images, we propose a novel method to reconstruct high-quality 4D cone-beam CT (4DCBCT) images from sparse datasets. Our approach combines the…

Medical Physics · Physics 2018-08-14 Joel Beaudry , Pedro L. Esquinas

Traditional X-ray computed tomography (CT) scanning strategies typically select projection angles uniformly and allocate dose equally. In practice, however, CT scans often need to be fast, radiation-efficient, and adaptive. Sparse-view…

Medical Physics · Physics 2026-04-24 Tianyuan Wang , Daniël M. Pelt , Felix Lucka , Tristan van Leeuwen , K. Joost Batenburg

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Diffusion Posterior Sampling(DPS) methodology is a novel framework that permits nonlinear CT reconstruction by integrating a diffusion prior and an analytic physical system model, allowing for one-time training for different applications.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiao Jiang , Shudong Li , Peiqing Teng , Grace Gang , J. Webster Stayman

Cone beam computed tomography (CBCT) is an important imaging technology widely used in medical scenarios, such as diagnosis and preoperative planning. Using fewer projection views to reconstruct CT, also known as sparse-view reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Yiqun Lin , Jiewen Yang , Hualiang Wang , Xinpeng Ding , Wei Zhao , Xiaomeng Li

Sparse-view computed tomography (CT) -- using a small number of projections for tomographic reconstruction -- enables much lower radiation dose to patients and accelerated data acquisition. The reconstructed images, however, suffer from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zilong Li , Chenglong Ma , Jie Chen , Junping Zhang , Hongming Shan

Sparse-view computed tomography (CT) reduces radiation exposure by acquiring fewer projections, making it a valuable tool in clinical scenarios where low-dose radiation is essential. However, this often results in increased noise and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Yingtai Li , Xueming Fu , Han Li , Shang Zhao , Ruiyang Jin , S. Kevin Zhou

With the availability of more powerful computing processors, iterative reconstruction algorithms have recently been successfully implemented as an approach to achieving significant dose reduction in X-ray CT. In this report, we describe our…

Medical Physics · Physics 2016-08-23 D. Trinca , Y. Zhong , Y. Wang , T. Mamyrbayev , E. Libin

As the medical usage of computed tomography (CT) continues to grow, the radiation dose should remain at a low level to reduce the health risks. Therefore, there is an increasing need for algorithms that can reconstruct high-quality images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Davood Karimi , Rabab K. Ward

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Intraoperative CT imaging serves as a crucial resource for surgical guidance; however, it may not always be readily accessible or practical to implement. In scenarios where CT imaging is not an option, reconstructing CT scans from X-rays…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Zhi Qiao , Xuhui Liu , Xiaopeng Wang , Runkun Liu , Xiantong Zhen , Pei Dong , Zhen Qian

We present MInDI-3D (Medical Inversion by Direct Iteration in 3D), the first 3D conditional diffusion-based model for real-world sparse-view Cone Beam Computed Tomography (CBCT) artefact removal, aiming to reduce imaging radiation exposure.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Daniel Barco , Marc Stadelmann , Martin Oswald , Ivo Herzig , Lukas Lichtensteiger , Pascal Paysan , Igor Peterlik , Michal Walczak , Bjoern Menze , Frank-Peter Schilling

In x-ray computed tomography (CT) it is generally acknowledged that reconstruction methods exploiting image sparsity allow reconstruction from a significantly reduced number of projections. The use of such reconstruction methods is…

Numerical Analysis · Mathematics 2014-08-05 Jakob S. Jørgensen , Emil Y. Sidky , Per Christian Hansen , Xiaochuan Pan

Compressive sensing(CS) has drawn much attention in recent years due to its low sampling rate as well as high recovery accuracy. As an important procedure, reconstructing a sparse signal from few measurement data has been intensively…

Information Theory · Computer Science 2018-06-25 Yicong He , Fei Wang , Shiyuan Wang , Badong Chen

Cold and generalized diffusion models have recently shown strong potential for sparse-view CT reconstruction by explicitly modeling deterministic degradation processes. However, existing sampling strategies often rely on ad hoc sampling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Yong Eun Choi , Hyoung Suk Park , Kiwan Jeon , Hyun-Cheol Park , Sung Ho Kang

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou