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Nonlinear registration of 2D histological sections with corresponding slices of MRI data is a critical step of 3D histology reconstruction. This task is difficult due to the large differences in image contrast and resolution, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Juan Eugenio Iglesias , Marc Modat , Loic Peter , Allison Stevens , Roberto Annunziata , Tom Vercauteren , Ed Lein , Bruce Fischl , Sebastien Ourselin

Recent developments in the registration of histology and micro-computed tomography ({\mu}CT) have broadened the perspective of pathological applications such as virtual histology based on {\mu}CT. This topic remains challenging because of…

Deformable image registration is a fundamental problem in the field of medical image analysis. During the last years, we have witnessed the advent of deep learning-based image registration methods which achieve state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Lucas Mansilla , Diego H. Milone , Enzo Ferrante

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

Deep learning based deformable registration methods have become popular in recent years. However, their ability to generalize beyond training data distribution can be poor, significantly hindering their usability. LUMIR brain registration…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Joel Honkamaa , Pekka Marttinen

While image registration has been studied in remote sensing community for decades, registering multimodal data [e.g., optical, LiDAR, SAR, and map] remains a challenging problem because of significant nonlinear intensity differences between…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Yuanxin Ye , Lorenzo Bruzzone , Jie Shan , Francesca Bovolo , Qing Zhu

Deformation field estimation is an important and challenging issue in many medical image registration applications. In recent years, deep learning technique has become a promising approach for simplifying registration problems, and has been…

Computer Vision and Pattern Recognition · Computer Science 2020-04-17 Yujia Zhou , Shumao Pang , Jun Cheng , Yuhang Sun , Yi Wu , Lei Zhao , Yaqin Liu , Zhentai Lu , Wei Yang , Qianjin Feng

Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Yan Hu , Mingdao Gong , Zhongxi Qiu , Jiabao Liu , Hongli Shen , Mingzhen Yuan , Xiaoqing Zhang , Heng Li , Hai Lu , Jiang Liu

This paper presents a novel technique for progressive online integration of uncalibrated image sequences with substantial geometric and/or photometric discrepancies into a single, geometrically and photometrically consistent image. Our…

Graphics · Computer Science 2019-09-11 Markus Kluge , Tim Weyrich , Andreas Kolb

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

Purpose: Diffeomorphic image registration is essential in many medical imaging applications. Several registration algorithms of such type have been proposed, but primarily for intra-contrast alignment. Currently, efficient…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Nima Masoumi , Hassan Rivaz , M. Omair Ahmad , Yiming Xiao

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

Multimodal registration is a challenging problem in medical imaging due the high variability of tissue appearance under different imaging modalities. The crucial component here is the choice of the right similarity measure. We make a step…

Computer Vision and Pattern Recognition · Computer Science 2016-09-20 Martin Simonovsky , Benjamín Gutiérrez-Becker , Diana Mateus , Nassir Navab , Nikos Komodakis

The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…

Image and Video Processing · Electrical Eng. & Systems 2019-09-09 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Deformable retinal image registration is notoriously difficult due to large homogeneous regions and sparse but critical vascular features, which cause limited gradient signals in standard learning-based frameworks. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xin Tian , Jiazheng Wang , Yuxi Zhang , Xiang Chen , Renjiu Hu , Gaolei Li , Min Liu , Hang Zhang

Deep learning has emerged as a strong alternative for classical iterative methods for deformable medical image registration, where the goal is to find a mapping between the coordinate systems of two images. Popular classical image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Joel Honkamaa , Pekka Marttinen

Conventional approaches to image registration consist of time consuming iterative methods. Most current deep learning (DL) based registration methods extract deep features to use in an iterative setting. We propose an end-to-end DL method…

Computer Vision and Pattern Recognition · Computer Science 2019-09-11 Dwarikanath Mahapatra

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

Learning non-rigid registration in an end-to-end manner is challenging due to the inherent high degrees of freedom and the lack of labeled training data. In this paper, we resolve these two challenges simultaneously. First, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wanquan Feng , Juyong Zhang , Hongrui Cai , Haofei Xu , Junhui Hou , Hujun Bao