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Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

Online convex optimization (OCO) with time-varying constraints is a critical framework for sequential decision-making in dynamic networked systems, where learners must minimize cumulative loss while satisfying regions of feasibility that…

Machine Learning · Computer Science 2026-03-17 Xiufeng Liu , Qian Chen , Zhijin Wang , Ruyu Liu

We consider distributionally robust optimization (DRO) problems, reformulated as distributionally robust feasibility (DRF) problems, with multiple expectation constraints. We propose a generic stochastic first-order meta-algorithm, where…

Optimization and Control · Mathematics 2023-05-29 Hyungki Im , Paul Grigas

Profile Guided Optimization (PGO) uses runtime profiling to direct compiler optimization decisions, effectively combining static analysis with actual execution behavior to enhance performance. Runtime profiles, collected through…

Performance · Computer Science 2025-07-23 Bingxin Liu , Yinghui Huang , Jianhua Gao , Jianjun Shi , Yongpeng Liu , Yipin Sun , Weixing Ji

The kick-one-out (KOO) method is a variable selection method based on a model selection criterion. The method is very simple, and yet it has consistency in variable selection under a high-dimensional asymptotic framework with a specific…

Methodology · Statistics 2025-09-16 M. Ohishi , R. Oda

A common goal in statistics and machine learning is to learn models that can perform well against distributional shifts, such as latent heterogeneous subpopulations, unknown covariate shifts, or unmodeled temporal effects. We develop and…

Machine Learning · Statistics 2020-07-21 John Duchi , Hongseok Namkoong

This paper proposes a model predictive controller for discrete-time linear systems with additive, possibly unbounded, stochastic disturbances and subject to chance constraints. By computing a polytopic probabilistic positively invariant set…

Optimization and Control · Mathematics 2024-09-23 Kai Wang , Kiet Tuan Hoang , Sébastien Gros

Identifying the relevant variables for a classification model with correct confidence levels is a central but difficult task in high-dimension. Despite the core role of sparse logistic regression in statistics and machine learning, it still…

Machine Learning · Statistics 2022-05-31 Binh T. Nguyen , Bertrand Thirion , Sylvain Arlot

Reinforcement learning with verifiable rewards (RLVR), due to the deterministic verification, becomes a dominant paradigm for enhancing the reasoning ability of large language models (LLMs). The community witnesses the rapid change from the…

Computation and Language · Computer Science 2026-05-08 Mingwei Xu , Hao Fang

Generative design marks a significant data-driven advancement in the exploration of novel inorganic materials, which entails learning the symmetry equivalent to the crystal structure prediction (CSP) task and subsequent learning of their…

Materials Science · Physics 2024-03-22 Ruiming Zhu , Wei Nong , Shuya Yamazaki , Kedar Hippalgaonkar

We survey continuous-time generative modeling methods based on transporting a simple reference distribution to a data distribution via stochastic or deterministic dynamics. We present a unified framework in which diffusion models,…

Machine Learning · Computer Science 2026-05-11 Aditya Ranganath , Mukesh Singhal

Offline reinforcement learning (RL) aims to optimize a policy by using pre-collected datasets, to maximize cumulative rewards. However, offline reinforcement learning suffers challenges due to the distributional shift between the learned…

Machine Learning · Computer Science 2025-03-10 Yunkai Gao , Jiaming Guo , Fan Wu , Rui Zhang

Consensus-based optimization (CBO) is a versatile multi-particle optimization method for performing nonconvex and nonsmooth global optimizations in high dimensions. Proofs of global convergence in probability have been achieved for a broad…

Optimization and Control · Mathematics 2026-01-13 Jonas Beddrich , Enis Chenchene , Massimo Fornasier , Hui Huang , Barbara Wohlmuth

The constrained version of the standard online convex optimization (OCO) framework, called COCO is considered, where on every round, a convex cost function and a convex constraint function are revealed to the learner after it chooses the…

Machine Learning · Computer Science 2025-02-11 Rahul Vaze , Abhishek Sinha

We consider Constrained Online Convex Optimization (COCO) with adversarially chosen constraints. At each round, the learner chooses an action before observing the loss and constraint function for that round. The goal is to achieve small…

Machine Learning · Computer Science 2026-05-21 Dhruv Sarkar , Abhishek Sinha

Uncertainties in transition dynamics pose a critical challenge in reinforcement learning (RL), often resulting in performance degradation of trained policies when deployed on hardware. Many robust RL approaches follow two strategies:…

Machine Learning · Computer Science 2026-01-29 Xulin Chen , Ruipeng Liu , Zhenyu Gan , Garrett E. Katz

In the field of global optimization, many existing algorithms face challenges posed by non-convex target functions and high computational complexity or unavailability of gradient information. These limitations, exacerbated by sensitivity to…

Optimization and Control · Mathematics 2023-10-16 Xinyu Zhang , Sujit Ghosh

The modern aerodynamic optimization has a strong demand for parametric methods with high levels of intuitiveness, flexibility, and representative accuracy, which cannot be fully achieved through traditional airfoil parametric techniques. In…

Fluid Dynamics · Physics 2023-05-08 Hairun Xie , Jing Wang , Miao Zhang

Statistical characteristics of deep network representations, such as sparsity and correlation, are known to be relevant to the performance and interpretability of deep learning. When a statistical characteristic is desired, often an…

Machine Learning · Computer Science 2019-03-04 Daeyoung Choi , Wonjong Rhee

Lipschitz one-dimensional constrained global optimization (GO) problems where both the objective function and constraints can be multiextremal and non-differentiable are considered in this paper. Problems, where the constraints are verified…

Optimization and Control · Mathematics 2011-07-27 Yaroslav D. Sergeyev , Dmitri E. Kvasov , Falah M. H. Khalaf