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Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

Computation and Language · Computer Science 2021-01-26 Ling Luo , Shankai Yan , Po-Ting Lai , Daniel Veltri , Andrew Oler , Sandhya Xirasagar , Rajarshi Ghosh , Morgan Similuk , Peter N. Robinson , Zhiyong Lu

Knowledge of the medical decision process, which can be modeled as medical decision trees (MDTs), is critical to build clinical decision support systems. However, the current MDT construction methods rely heavily on time-consuming and…

Computation and Language · Computer Science 2024-01-05 Wei Zhu , Wenfeng Li , Xing Tian , Pengfei Wang , Xiaoling Wang , Jin Chen , Yuanbin Wu , Yuan Ni , Guotong Xie

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

Despite the remarkable progress in the development of predictive models for healthcare, applying these algorithms on a large scale has been challenging. Algorithms trained on a particular task, based on specific data formats available in a…

Machine Learning · Computer Science 2023-11-16 Kyunghoon Hur , Jungwoo Oh , Junu Kim , Jiyoun Kim , Min Jae Lee , Eunbyeol Cho , Seong-Eun Moon , Young-Hak Kim , Louis Atallah , Edward Choi

Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient…

Artificial Intelligence · Computer Science 2021-04-13 Xingyao Zhang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Clinicians routinely navigate fragmented electronic health record (EHR) interfaces to assemble a coherent picture of a patient's problems, medications, recent encounters, and longitudinal trends. This manuscript describes EHRSummarizer, a…

Computation and Language · Computer Science 2026-05-27 Houman Kazemzadeh , Nima Minaifar , Kamyar Naderi , Sho Tabibzadeh

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

The challenge of recognizing named entities in a given text has been a very dynamic field in recent years. This is due to the advances in neural network architectures, increase of computing power and the availability of diverse labeled…

Computation and Language · Computer Science 2023-01-10 Nasi Jofche , Kostadin Mishev , Riste Stojanov , Milos Jovanovik , Dimitar Trajanov

The use of machine learning in Healthcare has the potential to improve patient outcomes as well as broaden the reach and affordability of Healthcare. The history of other application areas indicates that strong benchmarks are essential for…

Disease phenotyping algorithms process observational clinical data to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn…

Machine Learning · Computer Science 2019-03-27 Victor Rodriguez , Adler Perotte

Numerical time-series models can effectively process irregular electronic health record (EHR) trajectories, but they do not naturally expose the measurements and temporal patterns supporting each risk estimate as readable evidence. Existing…

Machine Learning · Computer Science 2026-05-21 Kwanhyung Lee , Juhwan Choi , Jongheon Kim , Joohyung Lee , Hyeongwon Jang , Eunho Yang

The target of Electronic Health Record (EHR) coding is to find the diagnostic codes according to the EHRs. In previous research, researchers have preferred to do multi-classification on the EHR coding task; most of them encode the EHR first…

Machine Learning · Computer Science 2026-01-21 Xiaofan Zhou

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

Enhancing clinical decision support (CDS), reducing documentation burdens, and improving patient health literacy remain persistent challenges in digital health. This paper presents an open-source, agent-based framework that integrates Large…

Software Engineering · Computer Science 2025-06-18 Abul Ehtesham , Aditi Singh , Saket Kumar

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

While text mining and NLP research has been established for decades, there remain gaps in the literature that reports the use of these techniques in building real-world applications. For example, they typically look at single and sometimes…

Computation and Language · Computer Science 2023-01-10 Ziqi Zhang , Tomas Jasaitis , Richard Freeman , Rowida Alfrjani , Adam Funk

Medication recommendation is a crucial task for assisting physicians in making timely decisions from longitudinal patient medical records. However, real-world EHR data present significant challenges due to the presence of rarely observed…

Artificial Intelligence · Computer Science 2025-08-15 Yan Ting Chok , Soyon Park , Seungheun Baek , Hajung Kim , Junhyun Lee , Jaewoo Kang

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

Computation and Language · Computer Science 2021-11-01 Bo Yang , Lijun Wu

Non-negative tensor factorization has been shown a practical solution to automatically discover phenotypes from the electronic health records (EHR) with minimal human supervision. Such methods generally require an input tensor describing…

Machine Learning · Computer Science 2020-11-13 Kejing Yin , William K. Cheung , Benjamin C. M. Fung , Jonathan Poon

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is…

Applications · Statistics 2026-01-01 Xin Gai , Shiyi Jiang , Anru R. Zhang