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Large Language Models have achieved remarkable success in language understanding and reasoning, and their multimodal extensions enable comprehension of images, video, and audio. Inspired by this, foundation models for brain functional…

Artificial Intelligence · Computer Science 2026-03-03 Xingcan Hu , Wei Wang , Li Xiao

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Large language models (LLMs) demonstrate remarkable ability to comprehend, reason, and generate following nature language instructions. However, the development of LLMs has been primarily focused on high-resource languages, such as English,…

In many-task optimization scenarios, surrogate models are valuable for mitigating the computational burden of repeated fitness evaluations across tasks. This study proposes a novel meta-surrogate framework to assist many-task optimization,…

Machine Learning · Computer Science 2026-02-05 Xian-Rong Zhang , Yue-Jiao Gong , Yuan-Ting Zhong , Ting Huang , Jun Zhang

Neurological disorders pose major global health challenges, driving advances in brain signal analysis. Scalp electroencephalography (EEG) and intracranial EEG (iEEG) are widely used for diagnosis and monitoring. However, dataset…

Neurons and Cognition · Quantitative Biology 2025-10-24 Jiahe Li , Xin Chen , Fanqi Shen , Junru Chen , Yuxin Liu , Daoze Zhang , Zhizhang Yuan , Fang Zhao , Meng Li , Yang Yang

Text generating capabilities have undergone a substantial transformation with the introduction of large language models (LLMs). Electroencephalography (EEG)-based text production is still difficult, though, because it requires a lot of data…

Human-Computer Interaction · Computer Science 2025-11-18 Khushiyant

Electroencephalogram (EEG) signals are pivotal in providing insights into spontaneous brain activity, highlighting their significant importance in neuroscience research. However, the exploration of versatile EEG models is constrained by…

Signal Processing · Electrical Eng. & Systems 2025-09-01 Tongtian Yue , Xuange Gao , Shuning Xue , Yepeng Tang , Longteng Guo , Jie Jiang , Jing Liu

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

Computation and Language · Computer Science 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

Large language models (LLMs) have demonstrated impressive capabilities across diverse languages. This study explores how LLMs handle multilingualism. Based on observed language ratio shifts among layers and the relationships between network…

Computation and Language · Computer Science 2024-11-12 Yiran Zhao , Wenxuan Zhang , Guizhen Chen , Kenji Kawaguchi , Lidong Bing

Large language models (LLMs) prompted with text and audio have achieved state-of-the-art performance across various auditory tasks, including speech, music, and general audio, showing emergent abilities on unseen tasks. However, their…

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

Multi-modal Large Language Model (MLLM) refers to a model expanded from a Large Language Model (LLM) that possesses the capability to handle and infer multi-modal data. Current MLLMs typically begin by using LLMs to decompose tasks into…

Computation and Language · Computer Science 2023-09-01 Yongqiang Zhao , Zhenyu Li , Feng Zhang , Xinhai Xu , Donghong Liu

Recent advancements in large language models (LLMs) have shown promising results in multilingual translation even with limited bilingual supervision. The major challenges are catastrophic forgetting and parameter interference for finetuning…

Computation and Language · Computer Science 2024-10-01 Shaolin Zhu , Leiyu Pan , Bo Li , Deyi Xiong

The remarkable success of large language models (LLMs) across various multi-modality applications is well established. However, integrating large language models with humans, or brain dynamics, remains relatively unexplored. In this paper,…

Signal Processing · Electrical Eng. & Systems 2024-09-04 Jinzhao Zhou , Yiqun Duan , Fred Chang , Thomas Do , Yu-Kai Wang , Chin-Teng Lin

The advent of multimodal large language models (MLLMs) has sparked interest in their application to electrocardiogram (ECG) analysis. However, existing ECG-focused MLLMs primarily focus on report generation tasks, often limited to single…

Computation and Language · Computer Science 2025-11-13 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

While large language models (LLMs) have demonstrated superior multi-task capabilities, understanding the learning mechanisms behind this is still a challenging problem. In this paper, we attempt to understand such mechanisms from the…

Computation and Language · Computer Science 2025-01-14 Yongqi Leng , Deyi Xiong

Foundation models (FMs) promise to extract unified representations that generalize across downstream tasks. They have emerged across fields, including electroencephalography (EEG), but it is less clear how effective they are in this…