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Finetuning a Large Language Model (LLM) is crucial for generating results towards specific objectives. This research delves into the realm of drug optimization and introduce a novel reinforcement learning algorithm to finetune a drug…

Machine Learning · Computer Science 2025-02-12 Xuefeng Liu , Songhao Jiang , Siyu Chen , Zhuoran Yang , Yuxin Chen , Ian Foster , Rick Stevens

The paper describes a system that uses large language model (LLM) technology to support the automatic learning of new entries in an intelligent agent's semantic lexicon. The process is bootstrapped by an existing non-toy lexicon and a…

Computation and Language · Computer Science 2023-12-29 Sanjay Oruganti , Sergei Nirenburg , Jesse English , Marjorie McShane

Benefiting from effective speech modeling, current Speech Large Language Models (SLLMs) have demonstrated exceptional capabilities in in-context speech generation and efficient generalization to unseen speakers. However, the prevailing…

Computation and Language · Computer Science 2024-01-26 Dong Zhang , Xin Zhang , Jun Zhan , Shimin Li , Yaqian Zhou , Xipeng Qiu

Materials design often relies on human-generated hypotheses, a process inherently limited by cognitive constraints such as knowledge gaps and limited ability to integrate and extract knowledge implications, particularly when…

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Humans can retain old knowledge while learning new information, but Large Language Models (LLMs) often suffer from catastrophic forgetting when post-pretrained or supervised fine-tuned (SFT) on domain-specific data. Moreover, for Multimodal…

Computation and Language · Computer Science 2026-04-24 Zilun Zhang , Yutao Sun , Tiancheng Zhao , Leigang Sha , Ruochen Xu , Kyusong Lee , Jianwei Yin

Having a unified, coherent taxonomy is essential for effective knowledge representation in domain-specific applications as diverse terminologies need to be mapped to underlying concepts. Traditional manual approaches to taxonomy alignment…

The increasing amount of published scholarly articles, exceeding 2.5 million yearly, raises the challenge for researchers in following scientific progress. Integrating the contributions from scholarly articles into a novel type of cognitive…

Digital Libraries · Computer Science 2024-09-12 Gollam Rabby , Sören Auer , Jennifer D'Souza , Allard Oelen

Large Language Models (LLMs) present massive inherent knowledge and superior semantic comprehension capability, which have revolutionized various tasks in natural language processing. Despite their success, a critical gap remains in…

Computation and Language · Computer Science 2025-02-11 Ben Liu , Jihai Zhang , Fangquan Lin , Cheng Yang , Min Peng

Large language models (LLMs) have demonstrated outstanding performance, making them valuable digital assets with significant commercial potential. Unfortunately, the LLM and its API are susceptible to intellectual property theft.…

Cryptography and Security · Computer Science 2024-07-25 Shuai Li , Kejiang Chen , Kunsheng Tang , Jie Zhang , Weiming Zhang , Nenghai Yu , Kai Zeng

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Large language models (LLMs) successfully model natural language from vast amounts of text without the need for explicit supervision. In this paper, we investigate the efficacy of LLMs in modeling passwords. We present PassGPT, a LLM…

Computation and Language · Computer Science 2023-06-16 Javier Rando , Fernando Perez-Cruz , Briland Hitaj

The remarkable capabilities and intricate nature of Artificial Intelligence (AI) have dramatically escalated the imperative for specialized AI accelerators. Nonetheless, designing these accelerators for various AI workloads remains both…

Machine Learning · Computer Science 2025-01-07 Yonggan Fu , Yongan Zhang , Zhongzhi Yu , Sixu Li , Zhifan Ye , Chaojian Li , Cheng Wan , Yingyan Celine Lin

Generative large language models (LLMs) can be a powerful tool for augmenting text annotation procedures, but their performance varies across annotation tasks due to prompt quality, text data idiosyncrasies, and conceptual difficulty.…

Computation and Language · Computer Science 2023-06-02 Nicholas Pangakis , Samuel Wolken , Neil Fasching

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Large Language Models (LLMs) possess human-level cognitive and decision-making capabilities, making them a key technology for 6G. However, applying LLMs to the communication domain faces three major challenges: 1) Inadequate communication…

Information Theory · Computer Science 2025-02-27 Feibo Jiang , Wanyun Zhu , Li Dong , Kezhi Wang , Kun Yang , Cunhua Pan , Octavia A. Dobre

Artificial intelligence (AI) methods have become critical in scientific applications to help accelerate scientific discovery. Large language models (LLMs) are being considered as a promising approach to address some of the challenging…

The capabilities of Large Language Models (LLMs) have opened new frontiers for interacting with complex, domain-specific knowledge. However, prevailing methods like Retrieval-Augmented Generation (RAG) and general-purpose Agentic AI, while…

Artificial Intelligence · Computer Science 2025-07-04 Guangwei Zhang

Knowledge retrieval with multi-modal queries plays a crucial role in supporting knowledge-intensive multi-modal applications. However, existing methods face challenges in terms of their effectiveness and training efficiency, especially when…

Information Retrieval · Computer Science 2024-01-17 Xinwei Long , Jiali Zeng , Fandong Meng , Zhiyuan Ma , Kaiyan Zhang , Bowen Zhou , Jie Zhou

Constraint Programming (CP) and Machine Learning (ML) face challenges in text generation due to CP's struggle with implementing "meaning'' and ML's difficulty with structural constraints. This paper proposes a solution by combining both…

Computation and Language · Computer Science 2024-09-26 Florian Régin , Elisabetta De Maria , Alexandre Bonlarron
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