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Bioinformatics pipelines depend on shared POSIX filesystems for its input, output and intermediate data storage. Containerization makes it more difficult for the workloads to access the shared file systems. In our previous study, we were…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-07-01 Yiannis Gkoufas , David Yu Yuan

Recent advances in large language models (LLMs) have enabled AI agents to autonomously generate scientific proposals, conduct experiments, author papers, and perform peer reviews. Yet this flood of AI-generated research content collides…

This paper introduces BioAgent Bench, a benchmark dataset and an evaluation suite designed for measuring the performance and robustness of AI agents in common bioinformatics tasks. The benchmark contains curated end-to-end tasks (e.g.,…

Artificial Intelligence · Computer Science 2026-05-08 Dionizije Fa , Marko Culjak , Bruno Pandza , Mateo Cupic

Modern biomedical applications often involve time-series data, from high-throughput phenotyping of model organisms, through to individual disease diagnosis and treatment using biomedical data streams. Data and tools for time-series analysis…

Databases · Computer Science 2019-05-06 Ben D. Fulcher , Carl H. Lubba , Sarab S. Sethi , Nick S. Jones

As scientific discovery becomes increasingly data-driven, software platforms are needed to efficiently organize and disseminate data from disparate sources. This is certainly the case in the field of materials science. For example,…

Software Engineering · Computer Science 2015-11-04 Patrick Huck , Anubhav Jain , Dan Gunter , Donald Winston , Kristin Persson

The reproducibility crisis in scientific computing constrains robotics research. Existing studies reveal that up to 70% of robotics algorithms cannot be reproduced by independent teams, while many others fail to reach deployment because…

We present BioSpark, a system for analogical innovation designed to act as a creativity partner in reducing the cognitive effort in finding, mapping, and creatively adapting diverse inspirations. While prior approaches have focused on…

Human-Computer Interaction · Computer Science 2025-03-14 Hyeonsu Kang , David Chuan-en Lin , Yan-Ying Chen , Matthew K. Hong , Nikolas Martelaro , Aniket Kittur

The SmartSHARK repository mining data is a collection of rich and detailed information about the evolution of software projects. The data is unique in its diversity and contains detailed information about each change, issue tracking data,…

Software Engineering · Computer Science 2021-08-05 Alexander Trautsch , Fabian Trautsch , Steffen Herbold

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

Context: Blockchain-based Information Ecosystems (BBIEs) are a type of information ecosystem in which blockchain technology is used to provide a trust mechanism among parties and to manage shared business logic, breaking the traditional…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-03 Francesco Salzano , Lodovica Marchesi , Remo Pareschi , Roberto Tonelli

The scale of biological datasets now routinely exceeds system memory, making data access rather than model computation the primary bottleneck in training machine-learning models. This bottleneck is particularly acute in biology, where…

Machine Learning · Computer Science 2026-04-06 Ilan Gold , Felix Fischer , Lucas Arnoldt , F. Alexander Wolf , Fabian J. Theis

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou

The healthcare system collects extensive data, encompassing patient administrative information, clinical measurements, and home-monitored health metrics. To support informed decision-making in patient care and treatment management, it is…

Human-Computer Interaction · Computer Science 2024-09-18 Faisal Zaki Roshan , Abhishek Ahuja , Fateme Rajabiyazdi

The increasing volumes of data produced by high-throughput instruments coupled with advanced computational infrastructures for scientific computing have enabled what is often called a {\em Fourth Paradigm} for scientific research based on…

Bioinformatics is a new discipline that addresses the need to manage and interpret the data that in the past decade was massively generated by genomic research. This discipline represents the convergence of genomics, biotechnology and…

Computational Engineering, Finance, and Science · Computer Science 2009-11-24 Sabu M. Thampi

In the past decade, tracking health trends using social media data has shown great promise, due to a powerful combination of massive adoption of social media around the world, and increasingly potent hardware and software that enables us to…

Computers and Society · Computer Science 2018-05-16 Martin Mueller , Marcel Salathé

Data science pipelines commonly utilize dataframe and array operations for tasks such as data preprocessing, analysis, and machine learning. The most popular tools for these tasks are pandas and NumPy. However, these tools are limited to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-20 Weizheng Lu , Kaisheng He , Xuye Qin , Chengjie Li , Zhong Wang , Tao Yuan , Xia Liao , Feng Zhang , Yueguo Chen , Xiaoyong Du

Study reproducibility is essential to corroborate, build on, and learn from the results of scientific research but is notoriously challenging in bioinformatics, which often involves large data sets and complex analytic workflows involving…

Quantitative Methods · Quantitative Biology 2023-05-22 Christopher R. Keefe , Matthew R. Dillon , Chloe Herman , Mary Jewell , Colin V. Wood , Evan Bolyen , J. Gregory Caporaso

AI-powered LizAI XT ensures real-time and accurate mega-structure of different clinical datasets and largely inaccessible and fragmented sources, into one comprehensive table or any designated forms, based on diseases, clinical variables,…

Computers and Society · Computer Science 2025-05-19 Trung Tin Nguyen , Salomon M. Stemmer , David R. Elmaleh

Modern science clearly demands for a higher level of reproducibility and collaboration. To make research fully reproducible one has to take care of several aspects: research protocol description, data access, environment preservation,…

Computers and Society · Computer Science 2017-12-06 Andrey Ustyuzhanin , Timothy Daniel Head , Igor Babuschkin , Alexander Tiunov
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