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Biology is at the precipice of a new era where AI accelerates and amplifies the ability to study how cells operate, organize, and work as systems, revealing why disease happens and how to correct it. Organizations globally are prioritizing…

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

Life sciences research increasingly requires identifying, accessing, and effectively processing data from an ever-evolving array of information sources on the Linked Open Data (LOD) network. This dynamic landscape places a significant…

Information Retrieval · Computer Science 2025-06-24 Syed N. Sakib , Kallol Naha , Sajratul Y. Rubaiat , Hasan M. Jamil

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…

Other Quantitative Biology · Quantitative Biology 2025-01-24 Himanshu Buckchash , Gyanendra Kumar Verma , Dilip K. Prasad

Life-science experimental methods generate vast and ever-increasing volumes of data, which provide highly valuable research resources. However, management of these data is nontrivial and applicable software solutions are currently subject…

The unprecedented size of the human population, along with its associated economic activities, have an ever increasing impact on global environments. Across the world, countries are concerned about the growing resource consumption and the…

Modern tools for biological research, especially microscopy, have rapidly advanced in recent years, which has led to the generation of increasingly large amounts of data on a regular basis. The result is that scientists desperately need…

Other Quantitative Biology · Quantitative Biology 2021-08-18 Andrey Andreev , Tom Morrell , Kristin Briney , Sandra Gesing , Uri Manor

The intrinsic complexity of human biology presents ongoing challenges to scientific understanding. Researchers collaborate across disciplines to expand our knowledge of the biological interactions that define human life. AI methodologies…

Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier

Biomedical research increasingly relies on heterogeneous, high-dimensional datasets, yet effective visualization remains hindered by fragmented code resources, steep programming barriers, and limited domain-specific guidance. Bizard is an…

A key goal of bioinformatics is to create database systems and software platforms capable of storing and analysing large sets of biological data. Hundreds of biological databases are now available and provide access to huge amount of…

Biologists are increasingly using databases for storing and managing their data. Biological databases typically consist of a mixture of raw data, metadata, sequences, annotations, and related data obtained from various sources. Current…

Databases · Computer Science 2007-05-23 Mohamed Y. Eltabakh , Mourad Ouzzani , Walid G. Aref

Research resources (RRs) such as data, software, and tools are essential pillars of scientific research. The field of biomedicine, a critical scientific discipline, is witnessing a surge in research publications resulting in the…

Digital Libraries · Computer Science 2024-09-24 Li Zhang , Mengting Sun , Chong Jiang , Haihua Chen

With high-throughput biotechnologies generating unprecedented quantities of data, researchers are faced with the challenge of locating and comparing an exponentially growing number of programs and websites dedicated to computational…

Over the past decade there has been a significant growth in bioinformatics databases, tools and resources. Although, bioinformatics is becoming more specific, increasing the number of bioinformatics-wares has made it difficult for…

Biobanks advance biomedical and clinical research by collecting and offering data and biological samples for numerous studies. However, the impact of these repositories varies greatly due to differences in their purpose, scope, governance,…

Quantitative Methods · Quantitative Biology 2024-07-02 Rodrigo Dorantes-Gilardi , Kerry Ivey , Lauren Costa , Rachael Matty , Kelly Cho , John Michael Gaziano , Albert-László Barabási

Data commons collate data with cloud computing infrastructure and commonly used software services, tools and applications to create biomedical resources for the large-scale management, analysis, harmonization, and sharing of biomedical…

Genomics · Quantitative Biology 2018-12-27 Robert L. Grossman
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