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Chemotaxis plays a crucial role in a variety of processes in biology and ecology. Quite often it acts to improve efficiency of biological reactions; one example is the immune system signalling, where infected tissues release chemokines…

Analysis of PDEs · Mathematics 2025-08-20 Jing An , Alexander Kiselev , Yao Yao

Keller-Segel systems in two and three space dimensions with an additional cross-diffusion term in the equation for the chemical concentration are analyzed. The cross-diffusion term has a stabilizing effect and leads to the global-in-time…

Analysis of PDEs · Mathematics 2019-07-29 Ansgar Jüngel , Oliver Leingang , Shu Wang

We derive general kinetic and hydrodynamic models of chemotactic aggregation that describe certain features of the morphogenesis of biological colonies (like bacteria, amoebae, endothelial cells or social insects). Starting from a…

Biological Physics · Physics 2009-11-13 Pierre-Henri Chavanis , Clement Sire

We consider a system of two coupled parabolic PDEs introduced in [1] to model motility of eukaryotic cells. We study the asymptotic behavior of solutions in the limit of a small parameter related to the width of the interface in phase field…

Analysis of PDEs · Mathematics 2016-02-05 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

We investigate the (reduced) Keller-Segel equations modeling chemotaxis of bio-organisms. We present a formal derivation and partial rigorous results of the blowup dynamics of solution of these equations describing the chemotactic…

Pattern Formation and Solitons · Physics 2014-07-03 S. I. Dejak , D. Egli , P. M. Lushnikov , I. M. Sigal

Autologous chemotaxis, in which cells secrete and detect molecules to determine the direction of fluid flow, is thwarted at high cell density because molecules from other cells interfere with a given cell's signal. Using a minimal model of…

Biological Physics · Physics 2022-09-14 Michael Vennettilli , Louis Gonzalez , Nicholas Hilgert , Andrew Mugler

This paper approaches the question of existence and uniqueness of stationary solutions to a semilinear hyperbolic-parabolic system and the study of the asymptotic behaviour of global solutions. The system is a model for some biological…

Analysis of PDEs · Mathematics 2017-07-11 Francesca Romana Guarguaglini

In this paper we consider a family of three-dimensional problems in thermoelasticity for linear elliptic membrane shells and study the asymptotic behaviour of the solution when the thickness tends to zero.We fully characterize with strong…

Analysis of PDEs · Mathematics 2020-12-22 M. T. Cao-Rial , G. Castiñeira , Á. Rodríguez-Arós , S. Roscani

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

Cell Behavior · Quantitative Biology 2026-02-24 Martina Conte , Romina Travaglini

Derived from a biophysical model for the motion of a crawling cell, the system \[(*)~\begin{cases}u_t=\Delta u-\nabla\cdot(u\nabla v)\\0=\Delta v-kv+u\end{cases}\] is investigated in a finite domain $\Omega\subset\mathbb{R}^n$, $n\geq2$,…

Analysis of PDEs · Mathematics 2021-01-19 Jan Fuhrmann , Johannes Lankeit , Michael Winkler

In this paper we deal with a semilinear hyperbolic chemotaxis model in one space dimension evolving on a network, with suitable transmission conditions at nodes. This framework is motivated by tissue-engineering scaffolds used for improving…

Numerical Analysis · Mathematics 2019-02-20 Gabriella Bretti , Roberto Natalini , Magali Ribot

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira

The general theory of a complex system of nonlinear chemical reactions is a primary language of chemistry that includes chemical engineering and cellular biochemistry. Its significance as an analytical framework, however, has not been fully…

Chemical Physics · Physics 2025-10-21 Liu Hong , Hong Qian

Cells perform directed motion in response to external stimuli that they detect by sensing the environment with their membrane protrusions. In particular, several biochemical and biophysical cues give rise to tactic migration in the…

Cell Behavior · Quantitative Biology 2020-07-15 N. Loy , M. Conte

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

Analysis of PDEs · Mathematics 2007-05-23 Radek Erban , Hyung Ju Hwang

We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modelling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or…

Dynamical Systems · Mathematics 2012-12-03 T. A. M. Langlands , B. I. Henry

This paper investigates a class of chemotaxis systems modeling lethal interactions in a smooth, bounded domain $\Omega \subset \mathbb{R}^n$ with homogeneous Neumann boundary conditions. We examine two distinct cases: (i) a fully parabolic…

Analysis of PDEs · Mathematics 2026-02-06 Gnanasekaran Shanmugasundaram , Jitraj Saha

This paper concerns a model for tumor cell migration through the surrounding extracellular matrix by considering mass balance phenomena involving the chemical interactions produced on the cell surface. The well-posedness of this model is…

Analysis of PDEs · Mathematics 2015-09-03 J. Nieto , L. Urrutia

This paper is devoted to constructing approximate solutions for the classical Keller--Segel model governing \emph{chemotaxis}. It consists of a system of nonlinear parabolic equations, where the unknowns are the average density of cells (or…

Numerical Analysis · Mathematics 2024-02-13 Juan Vicente Gutiérrez-Santacreu , José Rafael Rodríguez-Galván

We examine how the shape of cells and the geometry of experiment affect the reaction-diffusion kinetics at the binding between target and probe molecules on molecular biochips. In particular, we compare the binding kinetics for the probes…

Quantitative Methods · Quantitative Biology 2011-04-05 V. R. Chechetkin
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