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Segmentation of indicated targets aids in the precise analysis of optical coherence tomography angiography (OCTA) samples. Existing segmentation methods typically perform on 2D projection targets, making it challenging to capture the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Xinrun Chen , Chengliang Wang , Haojian Ning , Mengzhan Zhang , Mei Shen , Shiying Li

Background: Computed Tomography Angiography (CTA) is crucial for cerebrovascular disease diagnosis. Dynamic CTA is a type of imaging that captures temporal information about the We aim to develop and evaluate two segmentation techniques to…

Medical Physics · Physics 2025-02-17 Shrikanth Yadav , Jisoo Kim , Geoffrey Young , Lei Qin

Ancestry-specific proteome-wide association studies (PWAS) based on genetically predicted protein expression can reveal complex disease etiology specific to certain ancestral groups. These studies require ancestry-specific models for…

Applications · Statistics 2024-04-26 Aaron J. Molstad , Yanwei Cai , Alexander P. Reiner , Charles Kooperberg , Wei Sun , Li Hsu

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

The assessment of aortic valve pathology using magnetic resonance imaging (MRI) typically relies on blood velocity estimates acquired using phase contrast (PC) MRI. However, abnormalities in blood flow through the aortic valve often…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Y. On , K. Vimalesvaran , C. Galazis , S. Zaman , J. Howard , N. Linton , N. Peters , G. Cole , A. A. Bharath , M. Varela

Deep learning methods have contributed substantially to the rapid advancement of medical image segmentation, the quality of which relies on the suitable design of loss functions. Popular loss functions, including the cross-entropy and dice…

Image and Video Processing · Electrical Eng. & Systems 2022-11-07 Yucong Lin , Jinhua Su , Yuhang Li , Yuhao Wei , Hanchao Yan , Saining Zhang , Jiaan Luo , Danni Ai , Hong Song , Jingfan Fan , Tianyu Fu , Deqiang Xiao , Feifei Wang , Jue Hou , Jian Yang

The oxygen saturation level in the blood (SaO2) is crucial for health, particularly in relation to sleep-related breathing disorders. However, continuous monitoring of SaO2 is time-consuming and highly variable depending on patients'…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Zeyu Zhang , Xuyin Qi , Mingxi Chen , Guangxi Li , Ryan Pham , Ayub Qassim , Ella Berry , Zhibin Liao , Owen Siggs , Robert Mclaughlin , Jamie Craig , Minh-Son To

The mechanical properties of arterial walls are critical for maintaining vascular function under pulsatile pressure and are closely linked to the development of cardiovascular diseases. Despite advances in imaging and elastography,…

Biological Physics · Physics 2025-07-29 Yuxuan Jiang , Guo-Yang Li , Ruizhi Wang , Xu Feng , Yanhang Zhang , Seok-Hyun Yun

We investigated the feasibility and advantages of using non-contrast CT calcium score (CTCS) images to assess pericoronary adipose tissue (PCAT) and its association with major adverse cardiovascular events (MACE). PCAT features from…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Yingnan Song , Hao Wu , Juhwan Lee , Justin Kim , Ammar Hoori , Tao Hu , Vladislav Zimin , Mohamed Makhlouf , Sadeer Al-Kindi , Sanjay Rajagopalan , Chun-Ho Yun , Chung-Lieh Hung , David L. Wilson

The technology of optical coherence tomography (OCT) to fingerprint imaging opens up a new research potential for fingerprint recognition owing to its ability to capture depth information of the skin layers. Developing robust and high…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Wentian Zhang , Haozhe Liu , Feng Liu , Raghavendra Ramachandra

This study introduces a new framework for the artificial intelligence-assisted characterization of Gram-stained whole-slide images (WSIs). As a test for the diagnosis of bloodstream infections, Gram stains provide critical early data to…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Jack McMahon , Naofumi Tomita , Elizabeth S. Tatishev , Adrienne A. Workman , Cristina R Costales , Niaz Banaei , Isabella W. Martin , Saeed Hassanpour

Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Computed tomography (CT) can capture volumes large enough to measure a statistically meaningful number of micron-sized particles with a sufficiently good resolution to allow for the analysis of individual particles. However, the development…

Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Santiago Toledo-Cortés , Diego H. Useche , Fabio A. González

Clinical fusion of Single Photon Emission Computed Tomography Myocardial Perfusion Imaging (SPECT MPI) and Computed Tomography Angiography (CTA) remains limited by cross-modality misregistration and reliance on manual landmarks, which can…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ni Yao , Xiangyu Liu , Shaojie Tang , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Chengyang Li , Fubao Zhu , Chen Zhao , Zhihui Xu , Weihua Zhou

Cell segmentation is essential in biomedical research for analyzing cellular morphology and behavior. Deep learning methods, particularly convolutional neural networks (CNNs), have revolutionized cell segmentation by extracting intricate…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Boyuan Peng , Jiaju Chen , P. Bilha Githinji , Ijaz Gul , Qihui Ye , Minjiang Chen , Peiwu Qin , Xingru Huang , Chenggang Yan , Dongmei Yu , Jiansong Ji , Zhenglin Chen

While there have been increased researches using deep learning techniques for the extraction of vascular structure from the 2D en face OCTA, for such approach, it is known that the data annotation process on the curvilinear structure like…