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There has been a rapidly growing interest in Automatic Symptom Detection (ASD) and Automatic Diagnosis (AD) systems in the machine learning research literature, aiming to assist doctors in telemedicine services. These systems are designed…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Zhi Wen , Julien Martel , Joumana Ghosn

Differential Diagnosis (DDx) is the process of identifying the most likely medical condition among the possible pathologies through the process of elimination based on evidence. An automated process that narrows a large set of pathologies…

Machine Learning · Computer Science 2023-12-05 Mohammad Mahmudul Alam , Edward Raff , Tim Oates , Cynthia Matuszek

Automatic differential diagnosis (DDx) is an essential medical task that generates a list of potential diseases as differentials based on patient symptom descriptions. In practice, interpreting these differential diagnoses yields…

Computation and Language · Computer Science 2024-11-08 Shuang Zhou , Mingquan Lin , Sirui Ding , Jiashuo Wang , Genevieve B. Melton , James Zou , Rui Zhang

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…

Artificial Intelligence · Computer Science 2025-06-25 Lei Kang , Xuanshuo Fu , Oriol Ramos Terrades , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

Diagnosis-oriented dialogue system queries the patient's health condition and makes predictions about possible diseases through continuous interaction with the patient. A few studies use reinforcement learning (RL) to learn the optimal…

Computation and Language · Computer Science 2022-12-27 Wei Chen , Cheng Zhong , Jiajie Peng , Zhongyu Wei

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Automatic diagnosis has attracted increasing attention but remains challenging due to multi-step reasoning. Recent works usually address it by reinforcement learning methods. However, these methods show low efficiency and require…

Artificial Intelligence · Computer Science 2021-12-21 Junying Chen , Dongfang Li , Qingcai Chen , Wenxiu Zhou , Xin Liu

Early detection of retinal diseases is one of the most important means of preventing partial or permanent blindness in patients. In this research, a novel multi-label classification system is proposed for the detection of multiple retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 M. A. Rodriguez , H. AlMarzouqi , P. Liatsis

Cancer remains a global challenge due to its growing clinical and economic burden. Its uniquely personal manifestation, which makes treatment difficult, has fuelled the quest for personalized treatment strategies. Thus, genomic profiling is…

As dermatological conditions become increasingly common and the availability of dermatologists remains limited, there is a growing need for intelligent tools to support both patients and clinicians in the timely and accurate diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Ali Anaissi , Ali Braytee , Weidong Huang , Junaid Akram , Alaa Farhat , Jie Hua

Chronic pain is a global health challenge affecting millions of individuals, making it essential for physicians to have reliable and objective methods to measure the functional impact of clinical treatments. Traditionally used methods, like…

Machine Learning · Computer Science 2026-03-23 Yuanheng Mao , Lillian Yang , Stephen Yang , Ethan Shao , Zihan Li

An accurate differential diagnosis (DDx) is essential for patient care, shaping therapeutic decisions and influencing outcomes. Recently, Large Language Models (LLMs) have emerged as promising tools to support this process by generating a…

Artificial Intelligence · Computer Science 2025-10-07 Seungseop Lim , Gibaeg Kim , Hyunkyung Lee , Wooseok Han , Jean Seo , Jaehyo Yoo , Eunho Yang

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Clinical diagnosis is a complex cognitive process, grounded in dynamic cue acquisition and continuous expertise accumulation. Yet most current artificial intelligence (AI) systems are misaligned with this reality, treating diagnosis as…

Artificial Intelligence · Computer Science 2026-03-12 Ruiyang Ren , Yuhao Wang , Yunsen Liang , Lan Luo , Jing Liu , Haifeng Wang , Cong Feng , Yinan Zhang , Chunyan Miao , Ji-Rong Wen , Wayne Xin Zhao

This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Artificial Intelligence · Computer Science 2026-03-17 Muhammad Hammad Maqsood , Mubashir Sajid , Khubaib Ahmed , Muhammad Usamah Shahid , Muddassar Farooq

Medical dialogue systems have attracted growing research attention as they have the potential to provide rapid diagnoses, treatment plans, and health consultations. In medical dialogues, a proper diagnosis is crucial as it establishes the…

Computation and Language · Computer Science 2024-01-15 Kaishuai Xu , Wenjun Hou , Yi Cheng , Jian Wang , Wenjie Li

Voice disorders are pathologies significantly affecting patient quality of life. However, non-invasive automated diagnosis of these pathologies is still under-explored, due to both a shortage of pathological voice data, and diversity of the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Alkis Koudounas , Gabriele Ciravegna , Marco Fantini , Giovanni Succo , Erika Crosetti , Tania Cerquitelli , Elena Baralis

Multi-label learning predicts a subset of labels from a given label set for an unseen instance while considering label correlations. A known challenge with multi-label classification is the long-tailed distribution of labels. Many studies…

Machine Learning · Computer Science 2021-12-06 Vithya Yogarajan , Bernhard Pfahringer , Tony Smith , Jacob Montiel
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