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The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…
Retinal vessel segmentation serves as a critical prerequisite for automated diagnosis of retinal pathologies. While recent advances in Convolutional Neural Networks (CNNs) have demonstrated promising performance in this task, significant…
Objectives: To evaluate the performance of a deep learning based Artificial Intelligence (AI) software for detection of glaucoma from stereoscopic optic disc photographs, and to compare this performance to the performance of a large cohort…
Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…
Glioblastoma is a highly invasive brain tumor with rapid progression rates. Recent studies have shown that glioblastoma molecular subtype classification serves as a significant biomarker for effective targeted therapy selection. However,…
There is growing interest in concept-based models (CBMs) that combine high-performance and interpretability by acquiring and reasoning with a vocabulary of high-level concepts. A key requirement is that the concepts be interpretable.…
Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation…
Deep learning classifiers provide the most accurate means of automatically diagnosing diabetic retinopathy (DR) based on optical coherence tomography (OCT) and its angiography (OCTA). The power of these models is attributable in part to the…
In this manuscript, we present a robust method for glaucoma screening from fundus images using an ensemble of convolutional neural networks (CNNs). The pipeline comprises of first segmenting the optic disk and optic cup from the fundus…
Structural changes in main retinal blood vessels serve as critical biomarkers for the onset and progression of glaucoma. Identifying these vessels is vital for vascular modeling yet highly challenging. This paper proposes X-GAN, a…
Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…
In this work, we propose a special cascade network for image segmentation, which is based on the U-Net networks as building blocks and the idea of the iterative refinement. The model was mainly applied to achieve higher recognition quality…
Early-stage diabetic retinopathy (DR) presents challenges in clinical diagnosis due to inconspicuous and minute microangioma lesions, resulting in limited research in this area. Additionally, the potential of emerging foundation models,…
Glioblastoma brain tumors are highly malignant and often require early detection and accurate segmentation for effective treatment. We are proposing two deep learning models in this paper, namely UNet and Deeplabv3, for the detection and…
In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human…
Artificial Intelligence for RObust Glaucoma Screening (AIROGS) Challenge is held for developing solutions for glaucoma screening from color fundus photography that are robust to real-world scenarios. This report describes our method…
For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…
Retinoblastoma is the most prominent childhood primary intraocular malignancy that impacts the vision of children and adults worldwide. In contrasting and comparing with adults it is uveal melanoma. It is an aggressive tumor that can fill…
Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…
Deep learning techniques have shown their superior performance in dermatologist clinical inspection. Nevertheless, melanoma diagnosis is still a challenging task due to the difficulty of incorporating the useful dermatologist clinical…