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Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yiran Song , Yikai Zhang , Silvia Orengo-Nania , Nian Wang , Fenglong Ma , Rui Zhang , Yifan Peng , Mingquan Lin

Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Anirudh Prabhakaran , YeKun Xiao , Ching-Yu Cheng , Dianbo Liu

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wenbin Wei , Suyuan Yao , Cheng Huang , Xiangyu Gao

Automated Computer Aided diagnostic tools can be used for the early detection of glaucoma to prevent irreversible vision loss. In this work, we present a Multi-task Convolutional Neural Network (CNN) that jointly segments the Optic Disc…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Arunava Chakravarty , Jayanthi Sivswamy

Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Artem Sevastopolsky

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Peng Liu , Ruogu Fang

Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in…

Image and Video Processing · Electrical Eng. & Systems 2021-06-28 Gabriel García , Rocío del Amor , Adrián Colomer , Rafael Verdú-Monedero , Juan Morales-Sánchez , Valery Naranjo

Glaucoma is a progressive optic neuropathy characterized by structural damage to the optic nerve head and functional changes in the visual field. Detecting glaucoma early is crucial to preventing loss of eyesight. However, medical datasets…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Youssof Nawar , Nouran Soliman , Moustafa Wassel , Mohamed ElHabebe , Noha Adly , Marwan Torki , Ahmed Elmassry , Islam Ahmed

Scarcity of large publicly available retinal fundus image datasets for automated glaucoma detection has been the bottleneck for successful application of artificial intelligence towards practical Computer-Aided Diagnosis (CAD). A few small…

Image and Video Processing · Electrical Eng. & Systems 2020-06-17 Muhammad Naseer Bajwa , Gur Amrit Pal Singh , Wolfgang Neumeier , Muhammad Imran Malik , Andreas Dengel , Sheraz Ahmed

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Biomarker detection is an indispensable part of the diagnosis and treatment of low-grade glioma (LGG). However, current LGG biomarker detection methods rely on expensive and complex molecular genetic testing, for which professionals are…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Zijie Fang , Yihan Liu , Yifeng Wang , Xiangyang Zhang , Yang Chen , Changjing Cai , Yiyang Lin , Ying Han , Zhi Wang , Shan Zeng , Jun Tan , Yongbing Zhang , Hong Shen

Effectively stratifying patient risk in chronic diseases like glaucoma is a major clinical challenge. Clinicians need tools to identify patients at high risk of progression from sparse and irregularly-sampled electronic health records…

Machine Learning · Computer Science 2026-05-04 Bruce Rushing , Angela Danquah , Alireza Namazi , Arjun Dirghangi , Heman Shakeri

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Genomics · Quantitative Biology 2013-05-28 Yupeng Cun , Holger Fröhlich

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…

Glaucoma is a serious ocular disorder for which the screening and diagnosis are carried out by the examination of the optic nerve head (ONH). The color fundus image (CFI) is the most common modality used for ocular screening. In CFI, the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-05 Sharath M Shankaranarayana , Keerthi Ram , Kaushik Mitra , Mohanasankar Sivaprakasam

Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jihyun Moon , Charmgil Hong

Glioma, a prevalent and heterogeneous tumor originating from the glial cells, can be differentiated as Low Grade Glioma (LGG) and High Grade Glioma (HGG) according to World Health Organization's norms. Classifying gliomas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Kiranmayee Janardhan , Christy Bobby Thomas

Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Yan Luo , Min Shi , Yu Tian , Tobias Elze , Mengyu Wang

Fairness (also known as equity interchangeably) in machine learning is important for societal well-being, but limited public datasets hinder its progress. Currently, no dedicated public medical datasets with imaging data for fairness…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Yan Luo , Yu Tian , Min Shi , Louis R. Pasquale , Lucy Q. Shen , Nazlee Zebardast , Tobias Elze , Mengyu Wang