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Breast cancer is the most common cancer among women both in developed and developing countries. Early detection and diagnosis of breast cancer may reduce its mortality and improve the quality of life. Computer-aided detection (CADx) and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-23 Sokratis Makrogiannis , Chelsea E. Harris , Keni Zheng

Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these…

Human-Computer Interaction · Computer Science 2025-01-29 Olya Rezaeian , Alparslan Emrah Bayrak , Onur Asan

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

Machine Learning · Computer Science 2020-08-14 Anika Tabassum , Naimul Khan

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Eric Wu , Kevin Wu , William Lotter

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

Purpose: Segmentation of the breast lesion in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an essential step to accurately diagnose and plan treatment and monitor progress. This study aims to highlight the impact of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Sam Narimani , Solveig Roth Hoff , Kathinka Dahli Kurz , Kjell-Inge Gjesdal , Jurgen Geisler , Endre Grovik

Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide…

Machine Learning · Computer Science 2022-02-07 Panagiota Karatza , Kalliopi V. Dalakleidi , Maria Athanasiou , Konstantina S. Nikita

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple…

Machine Learning · Computer Science 2025-03-17 Omar Costilla-Reyes , Morgan Talbot

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker

Recent advances in attention-based multiple instance learning (MIL) have improved our insights into the tissue regions that models rely on to make predictions in digital pathology. However, the interpretability of these approaches is still…

Quantitative Methods · Quantitative Biology 2023-09-11 Willem Bonnaffé , CRUK ICGC Prostate Group , Freddie Hamdy , Yang Hu , Ian Mills , Jens Rittscher , Clare Verrill , Dan J. Woodcock

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

Unsupervised patient stratification is essential for disease subtype discovery, yet, despite growing evidence of molecular heterogeneity of non-oncological diseases, popular methods are benchmarked primarily using cancers with mutually…

Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiangcen Wu , Shaheer U. Saeed , Yipei Wang , Ester Bonmati Coll , Yipeng Hu

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

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