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We propose a novel method for establishing correspondence between two sequences of 2D images. One particular application of this technique is slice-level content navigation, where the goal is to localize specific 2D slices within a 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Dingjie Su , Weixiang Hong , Benoit M. Dawant , Bennett A. Landman

Spatial transcriptomics (ST) measures mRNA expression while preserving spatial organization, but multi-slice analysis faces two coupled difficulties: large non-rigid deformations across slices and inter-slice batch effects when alignment…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Bonian Han , Cong Qi , Przemyslaw Musialski , Zhi Wei

Synthesizing multimodality medical data provides complementary knowledge and helps doctors make precise clinical decisions. Although promising, existing multimodal brain graph synthesis frameworks have several limitations. First, they…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Islem Mhiri , Mohamed Ali Mahjoub , Islem Rekik

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

The task of spatial clustering of transcriptomics data is of paramount importance. It enables the classification of tissue samples into diverse subpopulations of cells, which, in turn, facilitates the analysis of the biological functions of…

Machine Learning · Computer Science 2025-07-29 Mehrad Soltani , Luis Rueda

Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to pathological features such as disease subtypes, it may…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Kazuya Nishimura , Ryoma Bise , Yasuhiro Kojima

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

Quantitative Methods · Quantitative Biology 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention…

Quantitative Methods · Quantitative Biology 2023-10-24 Chen Zhang , Junhui Gao , Lingxin Kong , Guangshuo cao , Xiangyu Guo , Wei Liu

Accurate spatio-temporal prediction is crucial for the sustainable development of smart cities. However, current approaches often struggle to capture important spatio-temporal relationships, particularly overlooking global relations among…

Machine Learning · Computer Science 2024-11-12 Ashutosh Sao , Simon Gottschalk

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Spatial transcriptomics enables genome-wide expression analysis within native tissue context, yet identifying spatial domains remains challenging due to complex gene-spatial interactions. Existing methods typically process spatial and…

Machine Learning · Computer Science 2025-12-19 Jianping Mei , Siqi Ai , Ye Yuan

Convolutional Neural Networks have become a cornerstone of medical image analysis due to their proficiency in learning hierarchical spatial features. However, this focus on a single domain is inefficient at capturing global, holistic…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Md. Saiful Bari Siddiqui , Mohammed Imamul Hassan Bhuiyan

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Graph convolutional network based methods that model the body-joints' relations, have recently shown great promise in 3D skeleton-based human motion prediction. However, these methods have two critical issues: first, deep graph convolutions…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Maosen Li , Siheng Chen , Zijing Zhang , Lingxi Xie , Qi Tian , Ya Zhang

For 3D spatial transcriptomics (ST), the high per-section acquisition cost of fully sampling every tissue section remains a significant challenge. Although recent approaches predict gene expression from histology images, these methods…

Image and Video Processing · Electrical Eng. & Systems 2025-07-30 Jiahe Qian , Yaoyu Fang , Xinkun Wang , Lee A. Cooper , Bo Zhou

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

Applications · Statistics 2023-12-14 Bencong Zhu , Guanyu Hu , Yang Xie , Lin Xu , Xiaodan Fan , Qiwei Li

This paper tackles the pressing challenge of mutagenicity prediction by introducing three ground-breaking approaches. First, it showcases the superior performance of 2D scattering coefficients extracted from molecular images, compared to…

Machine Learning · Computer Science 2024-11-26 Abdeljalil Zoubir , Badr Missaoui

Autonomous robotic systems and self driving cars rely on accurate perception of their surroundings as the safety of the passengers and pedestrians is the top priority. Semantic segmentation is one the essential components of environmental…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Ran Cheng , Ryan Razani , Ehsan Taghavi , Enxu Li , Bingbing Liu