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Hyperspectral image (HSI) plays a vital role in various fields such as agriculture and environmental monitoring. However, due to the expensive acquisition cost, the number of hyperspectral images is limited, degenerating the performance of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Li Pang , Xiangyong Cao , Datao Tang , Shuang Xu , Xueru Bai , Feng Zhou , Deyu Meng

Histopathology image synthesis plays an important role in tissue restoration, data augmentation, and modeling of tumor microenvironments. However, existing generative methods typically address restoration and generation as separate tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Xuan Xu , Prateek Prasanna

In recent years, diffusion models have emerged as a superior alternative to generative adversarial networks (GANs) for high-fidelity image generation, with wide applications in text-to-image generation, image-to-image translation, and…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Lorenzo Aloisi , Luigi Sigillo , Aurelio Uncini , Danilo Comminiello

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jonathan de Matos , Steve Tsham Mpinda Ataky , Alceu de Souza Britto , Luiz Eduardo Soares de Oliveira , Alessandro Lameiras Koerich

Hematoxylin and Eosin (H&E) staining is widely regarded as the standard in pathology for diagnosing diseases and tracking tumor recurrence. While H&E staining shows tissue structures, it lacks the ability to reveal specific proteins that…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Whole-slide image analysis is essential for diagnostic tasks in pathology, yet existing deep learning methods primarily rely on flat classification, ignoring hierarchical relationships among class labels. In this study, we propose HiClass,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Keunho Byeon , Jinsol Song , Seong Min Hong , Yosep Chong , Jin Tae Kwak

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Hematoxylin and Eosin (H&E) staining is the cornerstone of histopathology but lacks molecular specificity. While Immunohistochemistry (IHC) provides molecular insights, it is costly and complex, motivating H&E-to-IHC translation as a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Erik Großkopf , Valay Bundele , Mehran Hosseinzadeh , Hendrik P. A. Lensch

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

Medical image understanding requires meticulous examination of fine visual details, with particular regions requiring additional attention. While radiologists build such expertise over years of experience, it is challenging for AI models to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Ying Jin , Zhuoran Zhou , Haoquan Fang , Jenq-Neng Hwang

The emergence of digital pathology has opened new horizons for histopathology and cytology. Artificial-intelligence algorithms are able to operate on digitized slides to assist pathologists with diagnostic tasks. Whereas machine learning…

Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Jingsong Liu , Xiaofeng Deng , Han Li , Azar Kazemi , Christian Grashei , Gesa Wilkens , Xin You , Tanja Groll , Nassir Navab , Carolin Mogler , Peter J. Schüffler

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

Creating in-silico data with generative AI promises a cost-effective alternative to staining, imaging, and annotating whole slide images in computational pathology. Diffusion models are the state-of-the-art solution for generating in-silico…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Dominik Winter , Nicolas Triltsch , Marco Rosati , Anatoliy Shumilov , Ziya Kokaragac , Yuri Popov , Thomas Padel , Laura Sebastian Monasor , Ross Hill , Markus Schick , Nicolas Brieu

Existing deep learning-based approaches for histopathology image analysis require large annotated training sets to achieve good performance; but annotating histopathology images is slow and resource-intensive. Conditional generative…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Sujata Butte , Haotian Wang , Min Xian , Aleksandar Vakanski

Machine learning in computational pathology (CPath) often aggregates patch-level predictions from multi-gigapixel Whole Slide Images (WSIs) to generate WSI-level prediction scores for crucial tasks such as survival prediction and drug…

Machine Learning · Computer Science 2025-12-29 Piotr Keller , Muhammad Dawood , Brinder Singh Chohan , Fayyaz ul Amir Afsar Minhas

Ultra-high-resolution image synthesis holds significant potential, yet remains an underexplored challenge due to the absence of standardized benchmarks and computational constraints. In this paper, we establish Aesthetic-4K, a meticulously…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Jinjin Zhang , Qiuyu Huang , Junjie Liu , Xiefan Guo , Di Huang

Diffusion-based image generators can now produce high-quality and diverse samples, but their success has yet to fully translate to 3D generation: existing diffusion methods can either generate low-resolution but 3D consistent outputs, or…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Animesh Karnewar , Niloy J. Mitra , Andrea Vedaldi , David Novotny

In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng
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