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MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for…

Computer Vision and Pattern Recognition · Computer Science 2017-12-20 Jose Dolz , Christian Desrosiers , Li Wang , Jing Yuan , Dinggang Shen , Ismail Ben Ayed

The most recent fast and accurate image segmentation methods are built upon fully convolutional deep neural networks. In this paper, we propose new deep learning strategies for DenseNets to improve segmenting images with subtle differences…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Seyed Raein Hashemi , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

The automatic segmentation of perinatal brain structures in magnetic resonance imaging (MRI) is of utmost importance for the study of brain growth and related complications. While different methods exist for adult and pediatric MRI data,…

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal…

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

The development of automated tools for brain morphometric analysis in infants has lagged significantly behind analogous tools for adults. This gap reflects the greater challenges in this domain due to: 1) a smaller-scaled region of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Lilla Zöllei , Juan Eugenio Iglesias , Yangming Ou , P. Ellen Grant , Bruce Fischl

Neonatal brain segmentation in magnetic resonance (MR) is a challenging problem due to poor image quality and low contrast between white and gray matter regions. Most existing approaches for this problem are based on multi-atlas label…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Jose Dolz , Ismail Ben Ayed , Jing Yuan , Christian Desrosiers

Quantitative analysis of brain MRI at the age of 6 months is difficult because of the limited contrast between white matter and gray matter. In this study, we use a dilated triplanar convolutional neural network in combination with a…

Computer Vision and Pattern Recognition · Computer Science 2017-08-10 Pim Moeskops , Josien P. W. Pluim

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Haoran Dou , Davood Karimi , Caitlin K. Rollins , Cynthia M. Ortinau , Lana Vasung , Clemente Velasco-Annis , Abdelhakim Ouaalam , Xin Yang , Dong Ni , Ali Gholipour

Automatic segmentation in MR brain images is important for quantitative analysis in large-scale studies with images acquired at all ages. This paper presents a method for the automatic segmentation of MR brain images into a number of tissue…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Pim Moeskops , Max A. Viergever , Adriënne M. Mendrik , Linda S. de Vries , Manon J. N. L. Benders , Ivana Išgum

Automatic neonatal brain tissue segmentation in preterm born infants is a prerequisite for evaluation of brain development. However, automatic segmentation is often hampered by motion artifacts caused by infant head movements during image…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , E. Turk , M. Zreik , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Accurate tissue segmentation of thick-slice fetal brain magnetic resonance (MR) scans is crucial for both reconstruction of isotropic brain MR volumes and the quantification of fetal brain development. However, this task is challenging due…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Shijie Huang , Xukun Zhang , Zhiming Cui , He Zhang , Geng Chen , Dinggang Shen

Segmentation of magnetic resonance images (MRI) facilitates analysis of human brain development by delineating anatomical structures. However, in infants and young children, accurate segmentation is challenging due to development and…

Machine Learning · Computer Science 2026-04-01 Malte Hoffmann , Lilla Zöllei , Adrian V. Dalca

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Haoan Xu , Tianshu Zheng , Xinyi Xu , Yao Shen , Jiwei Sun , Cong Sun , Guangbin Wang , Zhaopeng Cui , Dan Wu

Accurate segmentation of MR brain tissue is a crucial step for diagnosis,surgical planning, and treatment of brain abnormalities. However,it is a time-consuming task to be performed by medical experts. So, automatic and reliable…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Yang Deng , Yao Sun , Yongpei Zhu , Mingwang Zhu , Wei Han , Kehong Yuan

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap
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