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Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

We present an approach to automatic detection of Alzheimer's type dementia based on characteristics of spontaneous spoken language dialogue consisting of interviews recorded in natural settings. The proposed method employs additive logistic…

Audio and Speech Processing · Electrical Eng. & Systems 2018-11-27 Saturnino Luz , Sofia de la Fuente , Pierre Albert

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

The use of spontaneous language to derive appropriate digital markers has become an emergent, promising and non-intrusive method to diagnose and monitor dementia. Here we propose methods to capture language coherence as a cost-effective,…

Computation and Language · Computer Science 2023-10-17 Dimitris Gkoumas , Adam Tsakalidis , Maria Liakata

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

Computation and Language · Computer Science 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…

Computation and Language · Computer Science 2021-09-27 Akshay Valsaraj , Ithihas Madala , Nikhil Garg , Veeky Baths

In recent years there has been a burgeoning interest in the use of computational methods to distinguish between elicited speech samples produced by patients with dementia, and those from healthy controls. The difference between perplexity…

Computation and Language · Computer Science 2020-06-30 Trevor Cohen , Serguei Pakhomov

Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech…

Computation and Language · Computer Science 2023-12-18 Zih-Jyun Lin , Yi-Ju Chen , Po-Chih Kuo , Likai Huang , Chaur-Jong Hu , Cheng-Yu Chen

Background: Subtle changes in spontaneous language production are among the earliest indicators of cognitive decline. Identifying linguistically interpretable markers of dementia can support transparent and clinically grounded screening…

Computation and Language · Computer Science 2026-02-12 Artsvik Avetisyan , Sachin Kumar

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Kaiying Lin , Peter Washington

Speech is a rich biomarker that encodes substantial information about the health of a speaker, and thus it has been proposed for the detection of numerous diseases, achieving promising results. However, questions remain about what the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Catarina Botelho , Alberto Abad , Tanja Schultz , Isabel Trancoso

In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

Computation and Language · Computer Science 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Early detection of dementia is critical for timely medical intervention and improved patient outcomes. Neuropsychological tests are widely used for cognitive assessment but have traditionally relied on manual scoring. Automatic dementia…

Machine Learning · Computer Science 2025-07-15 Liming Wang , Saurabhchand Bhati , Cody Karjadi , Rhoda Au , James Glass

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

Computation and Language · Computer Science 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni

This paper is a submission to the Alzheimer's Dementia Recognition through Spontaneous Speech (ADReSS) challenge, which aims to develop methods that can assist in the automated prediction of severity of Alzheimer's Disease from speech data.…

Machine Learning · Computer Science 2021-06-18 Morteza Rohanian , Julian Hough , Matthew Purver

Whisper fails to correctly transcribe dementia speech because persons with dementia (PwDs) often exhibit irregular speech patterns and disfluencies such as pauses, repetitions, and fragmented sentences. It was trained on standard speech and…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-29 Emmanuel Akinrintoyo , Nadine Abdelhalim , Nicole Salomons

Automated speech analysis is a thriving approach to detect early markers of Alzheimer's disease (AD). Yet, recording conditions in most AD datasets are heterogeneous, with patients and controls often evaluated in different acoustic…

Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…

Computation and Language · Computer Science 2023-07-18 M. Zakaria Kurdi