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Text-conditioned generative models for volumetric medical imaging provide semantic control but lack explicit anatomical guidance, often resulting in outputs that are spatially ambiguous or anatomically inconsistent. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Daniele Molino , Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

Ligand molecule conformation generation is a critical challenge in drug discovery. Deep learning models have been developed to tackle this problem, particularly through the use of generative models in recent years. However, these models…

Biomolecules · Quantitative Biology 2023-10-02 Jiamin Wu , He Cao , Yuan Yao

This technical report outlines our method for generating a synthetic dataset for semantic segmentation using a latent diffusion model. Our approach eliminates the need for additional models specifically trained on segmentation data and is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Felix Stillger , Frederik Hasecke , Tobias Meisen

Dichotomous Image Segmentation (DIS) tasks require highly precise annotations, and traditional dataset creation methods are labor intensive, costly, and require extensive domain expertise. Although using synthetic data for DIS is a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Haotian Qian , YD Chen , Shengtao Lou , Fahad Shahbaz Khan , Xiaogang Jin , Deng-Ping Fan

Multimodal learning has been demonstrated to enhance performance across various clinical tasks, owing to the diverse perspectives offered by different modalities of data. However, existing multimodal segmentation methods rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Shiyun Chen , Li Lin , Pujin Cheng , ZhiCheng Jin , JianJian Chen , HaiDong Zhu , Kenneth K. Y. Wong , Xiaoying Tang

Fundus imaging is a critical tool in ophthalmology, with different imaging modalities offering unique advantages. For instance, fundus fluorescein angiography (FFA) can accurately identify eye diseases. However, traditional invasive FFA…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Chengzhou Yu , Huihui Fang , Hongqiu Wang , Ting Deng , Qing Du , Yanwu Xu , Weihua Yang

Synthetic data generation has emerged as an invaluable solution in scenarios where real-world data collection and usage are limited by cost and scarcity. Large language models (LLMs) have demonstrated remarkable capabilities in producing…

Machine Learning · Computer Science 2025-07-22 Anh Nguyen , Sam Schafft , Nicholas Hale , John Alfaro

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Metastasis on lymph nodes (LNs), the most common way of spread for primary tumor cells, is a sign of increased mortality. However, metastatic LNs are time-consuming and challenging to detect even for professional radiologists due to their…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Chaoyi Wu , Feng Chang , Xiao Su , Zhihan Wu , Yanfeng Wang , Ling Zhu , Ya Zhang

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hazrat Ali , Shafaq Murad , Zubair Shah

Tumor synthesis enables the creation of artificial tumors in medical images, facilitating the training of AI models for tumor detection and segmentation. However, success in tumor synthesis hinges on creating visually realistic tumors that…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Qi Chen , Xiaoxi Chen , Haorui Song , Zhiwei Xiong , Alan Yuille , Chen Wei , Zongwei Zhou

An automatic evidential segmentation method based on Dempster-Shafer theory and deep learning is proposed to segment lymphomas from three-dimensional Positron Emission Tomography (PET) and Computed Tomography (CT) images. The architecture…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

The lane graph is critical for applications such as autonomous driving and lane-level route planning. While previous research has focused on extracting lane-level graphs from aerial imagery using convolutional neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Antonio Ruiz , Andrew Melnik , Nicolo Savioli , Dong Wang , Yanfeng Zhang , Helge Ritter

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

With the rapid development of artificial intelligence (AI), AI-assisted medical imaging analysis demonstrates remarkable performance in early lung cancer screening. However, the costly annotation process and privacy concerns limit the…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Yifan Jiang , Yannick Lemaréchal , Sophie Plante , Josée Bafaro , Jessica Abi-Rjeile , Philippe Joubert , Philippe Després , Venkata Manem

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua