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An approach to incorporate deep learning within an iterative image reconstruction framework to reconstruct images from severely incomplete measurement data is presented. Specifically, we utilize a convolutional neural network (CNN) as a…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Brendan Kelly , Thomas P. Matthews , Mark A. Anastasio

As Micro-CT technology continues to refine its characterization of material microstructures, industrial CT ultra-precision inspection is generating increasingly large datasets, necessitating solutions to the trade-off between accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Yipeng Yin , Rao Yao , Qingying Li , Dazhong Wang , Hong Zhou , Zhijun Fang , Jianing Chen , Longjie Qian , Mingyue Wu

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Longitudinal MRI is an important diagnostic imaging tool for evaluating the effects of treatment and monitoring disease progression. However, MRI, and particularly longitudinal MRI, is known to be time consuming. To accelerate imaging,…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Jens Renders , Banafshe Shafieizargar , Marleen Verhoye , Jan De Beenhouwer , Arnold J. den Dekker , Jan Sijbers

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in breast cancer screening, tumor assessment, and treatment planning and monitoring. The dynamic changes in contrast in different tissues help to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Rui Wang , Yuexi Du , John Lewin , R. Todd Constable , Nicha C. Dvornek

Segmenting anatomical structures in medical images has been successfully addressed with deep learning methods for a range of applications. However, this success is heavily dependent on the quality of the image that is being segmented. A…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Ilkay Oksuz , James R. Clough , Bram Ruijsink , Esther Puyol Anton , Aurelien Bustin , Gastao Cruz , Claudia Prieto , Andrew P. King , Julia A. Schnabel

Dual-energy CT (DECT) enables virtual monochromatic imaging (VMI) and improved contrast resolution, but its clinical adoption is limited by hardware complexity and cost. In this work, we propose a unified deep learning framework that…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Antony Jerald , Hemant K Aggarwal , Brian Nett , Avinash Gopal , Phaneendra K Yalavarthy , Bipul Das , Rajesh Langoju

The use of dual-energy CT (DECT) potentially decreases range uncertainties in proton and ion therapy treatment planning via determination of the involved physical target quantities. For eventual clinical application, the correct treatment…

Medical Physics · Physics 2016-05-19 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired…

Due to the energy-dependent nature of the attenuation coefficient and the polychromaticity of the X-ray source, beam hardening effect occurs when X-ray photons penetrate through an object, causing a nonlinear projection data. When a linear…

Medical Physics · Physics 2018-12-07 Wei Zhao , Dengwang Li , Kai Niu , Wenjian Qin , Hao Peng , Tianye Niu

Recent developments in high-power ultrafast optical technology and emerging theoretical frameworks in strong-field quantum electrodynamics (SF-QED) are unveiling nuanced differentiations between the semi-classical and full quantum…

Magnetic resonance (MR) and computer tomography (CT) images are two typical types of medical images that provide mutually-complementary information for accurate clinical diagnosis and treatment. However, obtaining both images may be limited…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Jiayuan Wang , Q. M. Jonathan Wu , Farhad Pourpanah

We present two methods that combine image reconstruction and edge detection in computed tomography (CT) scans. Our first method is as an extension of the prominent filtered backprojection algorithm. In our second method we employ…

Numerical Analysis · Mathematics 2021-10-14 Jürgen Frikel , Simon Göppel , Markus Haltmeier

In several image acquisition and processing steps of X-ray radiography, knowledge of the existence of metal implants and their exact position is highly beneficial (e.g. dose regulation, image contrast adjustment). Another application which…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Fuxin Fan , Ludwig Ritschl , Marcel Beister , Ramyar Biniazan , Björn Kreher , Tristan M. Gottschalk , Steffen Kappler , Andreas Maier

Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Neerav Karani , Ertunc Erdil , Krishna Chaitanya , Ender Konukoglu

Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Bo Zhou , Yu-Jung Tsai , Jiazhen Zhang , Xueqi Guo , Huidong Xie , Xiongchao Chen , Tianshun Miao , Yihuan Lu , James S. Duncan , Chi Liu

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

Image tokenization plays a central role in modern generative modeling by mapping visual inputs into compact representations that serve as an intermediate signal between pixels and generative models. Diffusion-based decoders have recently…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Chuhan Wang , Hao Chen

The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Weiwen Wu , Haijun Yu , Peijun Chen , Fulin Luo , Fenglin Liu , Qian Wang , Yining Zhu , Yanbo Zhang , Jian Feng , Hengyong Yu

Spectral computed tomography (CT) is an emerging technology capable of providing high chemical specificity, which is crucial for many applications such as detecting threats in luggage. This type of application requires both fast and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Wail Mustafa , Christian Kehl , Ulrik Lund Olsen , Søren Kimmer Schou Gregersen , David Malmgren-Hansen , Jan Kehres , Anders Bjorholm Dahl