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Recent advances in Language Models have enabled the protein modeling community with a powerful tool since protein sequences can be represented as text. Specifically, by taking advantage of Transformers, sequence-to-property prediction will…

Biomolecules · Quantitative Biology 2023-09-07 Chakradhar Guntuboina , Adrita Das , Parisa Mollaei , Seongwon Kim , Amir Barati Farimani

Statistical models for families of evolutionary related proteins have recently gained interest: in particular pairwise Potts models, as those inferred by the Direct-Coupling Analysis, have been able to extract information about the…

Biomolecules · Quantitative Biology 2019-09-25 Kai Shimagaki , Martin Weigt

We examine how the saccade mechanism from biological vision can be used to make deep neural networks more efficient for classification and object detection problems. Our proposed approach is based on the ideas of attention-driven visual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Saurabh Farkya , Zachary Daniels , Aswin Nadamuni Raghavan , David Zhang , Michael Piacentino

We present a coarse-grained model for evaluation of interactions of globular proteins with nanoparticles. The protein molecules are represented by one bead per aminoacid and the nanoparticle by a homogeneous sphere that interacts with the…

Soft Condensed Matter · Physics 2016-11-22 Hender Lopez , Vladimir Lobaskin

In chemical processing and bioprocessing, conventional online sensors are limited to measure only basic process variables like pressure and temperature, pH, dissolved O and CO$_2$ and viable cell density (VCD). The concentration of other…

Quantitative Methods · Quantitative Biology 2020-05-07 Semion Rozov

A challenging part of dynamic probabilistic risk assessment for nuclear power plants is the need for large amounts of temporal simulations given various initiating events and branching conditions from which representative feature extraction…

Machine Learning · Computer Science 2021-04-20 Bing Zha , Alessandro Vanni , Yassin Hassan , Tunc Aldemir , Alper Yilmaz

The global rise in type 2 diabetes underscores the need for scalable and cost-effective screening methods. Current diagnosis requires biochemical assays, which are invasive and costly. Advances in consumer wearables have enabled early…

Sparse sequences of neural spikes are posited to underlie aspects of working memory, motor production, and learning. Discovering these sequences in an unsupervised manner is a longstanding problem in statistical neuroscience. Promising…

Machine Learning · Statistics 2020-10-13 Alex H. Williams , Anthony Degleris , Yixin Wang , Scott W. Linderman

Fluids under nanoscale confinement differ -- and often dramatically -- from their bulk counterparts. A notorious feature of nanoconfined fluids is their inhomogeneous density profile along the confining dimension, which plays a key role in…

Soft Condensed Matter · Physics 2025-08-26 Yuanhao Li

Over the last decade, many experiments have demonstrated that nanobiosensors based on Nanotubes and Nanowires are significantly more sensitive compared to their planar counterparts. Yet, there has been persistent gap between reports of…

Biological Physics · Physics 2009-01-29 Jonghyun Go , Muhammad A. Alam

In the emerging field of DNA storage, data is encoded as DNA sequences and stored. The data is read out again by sequencing the stored DNA. Nanopore sequencing is a new sequencing technology that has many advantages over other methods; in…

Information Theory · Computer Science 2021-02-04 Reyna Hulett , Shubham Chandak , Mary Wootters

In the domain of time series analysis, particularly in event detection tasks, current methodologies predominantly rely on segmentation-based approaches, which predict the class label for each individual timesteps and use the changepoints of…

Artificial Intelligence · Computer Science 2024-08-26 Clark Peng , Tolga Dinçer

We present Patherea, a unified framework for point-based cell detection and classification that enables the development and fair evaluation of state-of-the-art methods. To support this, we introduce a large-scale dataset that replicates the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Dejan Štepec , Maja Jerše , Snežana Đokić , Jera Jeruc , Nina Zidar , Danijel Skočaj

Protein representation learning is a challenging task that aims to capture the structure and function of proteins from their amino acid sequences. Previous methods largely ignored the fact that not all amino acids are equally important for…

Machine Learning · Computer Science 2024-04-02 Ruijie Quan , Wenguan Wang , Fan Ma , Hehe Fan , Yi Yang

The detection and classification of microplastics in water remain a significant challenge due to their diverse properties and the limitations of traditional optical methods. Standard spectroscopic techniques often suffer from the strong…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Leonard Saur , Marc von Pawlowski , Ulrich Gengenbach , Ingo Sieber , Hossein Shirali , Lorenz Wührl , Xiangyu Weng , Rainer Kiko , Christian Pylatiuk

De novo peptide sequencing is a critical task in proteomics. However, the performance of current deep learning-based methods is limited by the inherent complexity of mass spectrometry data and the heterogeneous distribution of noise…

Machine Learning · Computer Science 2025-06-02 Zijie Qiu , Jiaqi Wei , Xiang Zhang , Sheng Xu , Kai Zou , Zhi Jin , Zhiqiang Gao , Nanqing Dong , Siqi Sun

This contribution presents a parameter identification methodology for the accurate and fast estimation of model parameters in a pseudo-two-dimensional (P2D) battery model. The methodology consists of three key elements. First, the data for…

Systems and Control · Electrical Eng. & Systems 2025-07-21 L. D. Couto , K. Haghverdi , F. Guo , K. Trad , G. Mulder

The volume of data generated by internet and social networks is increasing every day, and there is a clear need for efficient ways of extracting useful information from them. As those data can take different forms, it is important to use…

Machine Learning · Statistics 2017-05-25 Bertrand Lebichot , Marco Saerens

The robust detection of statistical dependencies between the components of a complex system is a key step in gaining a network-based understanding of the system. Because of their simplicity and low computation cost, pairwise statistics are…

Statistics Theory · Mathematics 2019-08-01 Antoine Messager , Nicos Georgiou , Luc Berthouze

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun
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