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The "IMP Science Gateway Portal" (http://scigate.imp.kiev.ua) for complex workflow management and integration of distributed computing resources (like clusters, service grids, desktop grids, clouds) is presented. It is created on the basis…

Computational Engineering, Finance, and Science · Computer Science 2014-04-23 Yuri Gordienko , Lev Bekenov , Olexandr Gatsenko , Elena Zasimchuk , Valentin Tatarenko

Cross-validation (CV) is one of the most popular tools for assessing and selecting predictive models. However, standard CV suffers from high computational cost when the number of folds is large. Recently, under the empirical risk…

Methodology · Statistics 2023-05-30 Yuetian Luo , Zhimei Ren , Rina Foygel Barber

The Reinforcement Learning (RL) paradigm has been an essential tool for automating robotic tasks. Despite the advances in RL, it is still not widely adopted in the industry due to the need for an expensive large amount of robot interaction…

Recent advancements in parallel simulation and successful robotic applications are spurring a resurgence in sampling-based model predictive control. To build on this progress, however, the robotics community needs common tooling for…

Robotics · Computer Science 2025-06-23 Albert H. Li , Brandon Hung , Aaron D. Ames , Jiuguang Wang , Simon Le Cleac'h , Preston Culbertson

The use of random sampling in decision-making and control has become popular with the ease of access to graphic processing units that can generate and calculate multiple random trajectories for real-time robotic applications. In contrast to…

Robotics · Computer Science 2022-03-21 Hyung-Jin Yoon , Chuyuan Tao , Hunmin Kim , Naira Hovakimyan , Petros Voulgaris

A new self-learning algorithm for accelerated dynamics, reconnaissance metadynamics, is proposed that is able to work with a very large number of collective coordinates. Acceleration of the dynamics is achieved by constructing a bias…

Computational Physics · Physics 2010-10-15 Gareth A. Tribello , Michele Ceriotti , Michele Parrinello

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

Efficient sampling in biomolecular simulations is critical for accurately capturing the complex dynamical behaviors of biological systems. Adaptive sampling techniques aim to improve efficiency by focusing computational resources on the…

Biomolecules · Quantitative Biology 2024-10-22 Hassan Nadeem , Diwakar Shukla

Decades of hardware, methodological, and algorithmic development have propelled molecular dynamics (MD) simulations to the forefront of materials-modeling techniques, bridging the gap between electronic-structure theory and continuum…

Soft Condensed Matter · Physics 2020-11-11 Tristan Bereau

This paper investigates distributed computing and cooperative control of connected and automated vehicles (CAVs) in ramp merging scenario under transportation cyber-physical system. Firstly, a centralized cooperative trajectory planning…

Systems and Control · Electrical Eng. & Systems 2024-10-31 Qiong Wu , Jiahou Chu , Pingyi Fan , Kezhi Wang , Nan Cheng , Wen Chen , Khaled B. Letaief

Accelerated molecular dynamics (MD) simulations are implemented to model the sliding process of AFM experiments at speeds close to those found in experiment. In this study the hyperdynamics method, originally devised to extend MD time…

Materials Science · Physics 2015-05-14 Woo Kyun Kim , Michael L. Falk

Virtualization technology allows currently any application run any application complex and expensive computational (the scientific applications are a good example) on heterogeneous distributed systems, which make regular use of Grid and…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-08-03 Tomas Ramirez Picarzo , Francisco Fernandez de Vega , Daniel Lombrana Gonzalez

This paper presents a molecular mechanics study using a molecular dynamics software (NAMD) coupled to virtual reality (VR) techniques for intuitive Bio-NanoRobotic prototyping. Using simulated Bio-Nano environments in VR, the operator can…

Biological Physics · Physics 2007-08-15 Mustapha Hamdi , Gaurav Sharma , A. Ferreira , Constantinos Mavroidis

Understanding decision-making in clinical environments is of paramount importance if we are to bring the strengths of machine learning to ultimately improve patient outcomes. Several factors including the availability of public data, the…

Machine Learning · Computer Science 2022-03-15 Alex J. Chan , Ioana Bica , Alihan Huyuk , Daniel Jarrett , Mihaela van der Schaar

Evaluating models fit to data with internal spatial structure requires specific cross-validation (CV) approaches, because randomly selecting assessment data may produce assessment sets that are not truly independent of data used to train…

Computation · Statistics 2023-03-14 Michael J Mahoney , Lucas K Johnson , Julia Silge , Hannah Frick , Max Kuhn , Colin M Beier

Prototyping HPC systems with low-to-mid technology readiness level (TRL) systems is critical for providing feedback to hardware designers, the system software team (e.g., compiler developers), and early adopters from the scientific…

Docking-based virtual screening (VS process) selects ligands with potential pharmacological activities from millions of molecules using computational docking methods, which greatly could reduce the number of compounds for experimental…

Quantitative Methods · Quantitative Biology 2021-10-26 Wei Ma , Qin Xie , Jianhang Zhang , Shiliang Li , Youjun Xu , Xiaobing Deng , Weilin Zhang

This paper discusses our proposal and implementation of Distill, a domain-specific compilation tool based on LLVM to accelerate cognitive models. Cognitive models explain the process of cognitive function and offer a path to human-like…

Programming Languages · Computer Science 2022-01-17 Jan Vesely , Raghavendra Pradyumna Pothukuchi , Ketaki Joshi , Samyak Gupta , Jonathan D. Cohen , Abhishek Bhattacharjee

As customized accelerator design has become increasingly popular to keep up with the demand for high performance computing, it poses challenges for modern simulator design to adapt to such a large variety of accelerators. Existing…

Programming Languages · Computer Science 2022-02-03 Zhijing Li , Yuwei Ye , Stephen Neuendorffer , Adrian Sampso

The safety of Automated Vehicles (AVs) must be assured before their release and deployment. The current approach to evaluation relies primarily on (i) testing AVs on public roads or (ii) track testing with scenarios defined in a test…

Other Computer Science · Computer Science 2017-02-21 Ding Zhao , Xianan Huang , Huei Peng , Henry Lam , David J. LeBlanc