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Free energy calculations are at the heart of physics-based analyses of biochemical processes. They allow us to quantify molecular recognition mechanisms, which determine a wide range of biological phenomena from how cells send and receive…

Recent advances in quantum computing have brought us closer to realizing the potential of this transformative technology. While significant strides have been made in quantum error correction, many challenges persist, particularly in the…

Quantum Physics · Physics 2025-12-03 Mateusz Meller , Vendel Szeremi , Oliver Thomson Brown

Quantum computing is rapidly emerging as a promising technology for solving complex optimization problems that arise in various engineering fields. Therefore, it holds significant promise to transform the computational foundations of power…

Quantum Physics · Physics 2026-01-06 Nikolaos G. Paterakis , Petros Karamanakos , Corey O'Meara , Georgios Papafotiou

Programming for today's quantum computers is making significant strides toward modern workflows compatible with high performance computing (HPC), but fundamental challenges still remain in the integration of these vastly different…

Quantum computing is a game-changing technology for global academia, research centers and industries including computational science, mathematics, finance, pharmaceutical, materials science, chemistry and cryptography. Although it has seen…

Quantum Physics · Physics 2023-03-07 He-Liang Huang , Xiao-Yue Xu , Chu Guo , Guojing Tian , Shi-Jie Wei , Xiaoming Sun , Wan-Su Bao , Gui-Lu Long

Quantum computing technology is advancing rapidly. Yet, even accounting for these trends, a quantum leap would be needed for quantum computers to meaningfully impact deep learning over the coming decade or two. We arrive at this conclusion…

Quantum Physics · Physics 2025-11-04 Hans Gundlach , Hrvoje Kukina , Jayson Lynch , Neil Thompson

Quantum computers are becoming real, and they have the inherent potential to significantly impact many application domains. We sketch the basics about programming quantum computers, showing that quantum programs are typically hybrid…

Simulating chemical systems is highly sought after and computationally challenging, as the number of degrees of freedom increases exponentially with the size of the system. Quantum computers have been proposed as a computational means to…

Quantum computing has shown promise for solving complex optimization problems in databases, such as join ordering and index selection. Prior work often submits formulated problems directly to black-box quantum or quantum-inspired solvers…

Databases · Computer Science 2026-02-17 Hanwen Liu , Ibrahim Sabek

The magnificence grandeur of quantum computing lies in the inherent nature of quantum particles to exhibit true parallelism, which can be realized by indubitably fascinating theories of quantum physics. The possibilities opened by quantum…

Emerging Technologies · Computer Science 2020-10-19 Nivedita Dey , Mrityunjay Ghosh , Subhra Samir kundu , Amlan Chakrabarti

The rapid and successful strides in quantum chemistry in the past decades can be largely credited to a conspicuous synergy between theoretical and computational advancements. However, the architectural computer archetype that enabled such a…

Quantum Physics · Physics 2024-06-06 Daniel Claudino

The complexity of large-scale 6G-and-beyond networks demands innovative approaches for multi-objective optimization over vast search spaces, a task often intractable. Quantum computing (QC) emerges as a promising technology for efficient…

Networking and Internet Architecture · Computer Science 2025-09-10 Sebastian Macaluso , Giovanni Geraci , Elías F. Combarro , Sergi Abadal , Ioannis Arapakis , Sofia Vallecorsa , Eduard Alarcón

Quantum computing exhibits the unique capability to natively and efficiently encode various natural phenomena, promising theoretical speedups of several orders of magnitude. However, not all computational tasks can be efficiently executed…

Software Engineering · Computer Science 2025-04-28 Vincenzo De Maio , Ivona Brandic , Ewa Deelman , Jürgen Cito

Recently, increased computational power and data availability, as well as algorithmic advances, have led machine learning techniques to impressive results in regression, classification, data-generation and reinforcement learning tasks.…

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

Artificial intelligence (AI) has sparked immense interest in drug discovery, but most current approaches only digitize existing high-throughput experiments. They remain constrained by conventional pipelines. As a result, they do not address…

Computers and Society · Computer Science 2025-07-29 You Wu , Philip E. Bourne , Lei Xie

Significant progress in the development of efficient and fast algorithms for quantum chemical calculations has been made in the past two decades. The main focus has always been the desire to be able to treat ever larger molecules or…

Chemical Physics · Physics 2012-12-18 Moritz P. Haag , Markus Reiher

Quantum circuit simulation is crucial for the development of quantum algorithms, particularly given the high cost and noise limitations of physical quantum hardware. While full-state quantum circuit simulation is commonly employed for…

Quantum Physics · Physics 2026-04-15 Chuan-Chi Wang , Yan-Jie Wang , Chia-Heng Tu , Shih-Hao Hung

Quantum computing applications are an emerging field in high-energy physics. Its ambitious fusion with artificial intelligence is expected to deliver significant efficiency gains over existing methods and/or enable computation from a…

Quantum Physics · Physics 2025-11-24 Hideki Okawa

This paper explores the transformative potential of quantum computing in the realm of personalized learning. Traditional machine learning models and GPU-based approaches have long been utilized to tailor educational experiences to…

Quantum Physics · Physics 2024-08-29 Yifan Zhou , Chong Cheng Xu , Mingi Song , Yew Kee Wong
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