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Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to…

Social and Information Networks · Computer Science 2018-01-08 Ashwin Paranjape , Austin R. Benson , Jure Leskovec

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

Neurons and Cognition · Quantitative Biology 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

Studying the topology of so-called real networks, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that networks are…

Applications · Statistics 2010-07-27 Etienne Birmele

A deluge of new data on social, technological and biological networked systems suggests that a large number of interactions among system units are not limited to pairs, but rather involve a higher number of nodes. To properly encode such…

Physics and Society · Physics 2023-11-08 Quintino Francesco Lotito , Federico Musciotto , Alberto Montresor , Federico Battiston

A new heuristic based on vertex invariants is developed to rapidly distinguish non-isomorphic graphs to a desired level of accuracy. The method is applied to sample subgraphs from an E.coli protein interaction network, and as a probe for…

Quantitative Methods · Quantitative Biology 2009-11-13 Kim Baskerville , Maya Paczuski

Caenorhabditis elegans (C. elegans) illustrated remarkable behavioral plasticities including complex non-associative and associative learning representations. Understanding the principles of such mechanisms presumably leads to constructive…

Neurons and Cognition · Quantitative Biology 2017-03-28 Ramin M. Hasani , Magdalena Fuchs , Victoria Beneder , Radu Grosu

Network community detection is a hot research topic in network analysis. Although many methods have been proposed for community detection, most of them only take into consideration the lower-order structure of the network at the level of…

Social and Information Networks · Computer Science 2019-06-12 Pei-Zhen Li , Ling Huang , Chang-Dong Wang , Jian-Huang Lai

Computational approaches which emulate in-vivo nervous system are needed to investigate mechanisms of the brain to orchestrate behavior. Such approaches must integrate a series of biophysical models encompassing the nervous system, muscles,…

Quantitative Methods · Quantitative Biology 2025-06-05 Jimin Kim , Jeremy T. Florman , Julia A. Santos , Mark J. Alkema , Eli Shlizerman

Studying the topology of so-called {\em real networks}, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that…

Applications · Statistics 2010-11-23 Etienne Birmele

Motif counting plays a crucial role in understanding the structural properties of networks. By computing motif frequencies, researchers can draw key insights into the structural properties of the underlying network. As networks become…

Social and Information Networks · Computer Science 2025-03-26 Haozhe Yin , Kai Wang , Wenjie Zhang , Yizhang He , Ying Zhang , Xuemin Lin

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise…

Neurons and Cognition · Quantitative Biology 2018-05-29 Emma K. Towlson , Petra E. Vertes , Gang Yan , Yee Lian Chew , Denise S. Walker , William R. Schafer , Albert-Laszlo Barabasi

Deep neural networks excel in mapping genomic DNA sequences to associated readouts (e.g., protein-DNA binding). Beyond prediction, the goal of these networks is to reveal to scientists the underlying motifs (and their syntax) which drive…

Genomics · Quantitative Biology 2024-10-10 Alex M. Tseng , Gokcen Eraslan , Tommaso Biancalani , Gabriele Scalia

There is renewed interest in modeling and understanding the nervous system of the nematode $\textit{Caenorhabditis elegans}$ ($\textit{C. elegans}$), as this small model system provides a path to bridge the gap between nervous system…

Neurons and Cognition · Quantitative Biology 2025-05-20 Quilee Simeon , Anshul Kashyap , Konrad P Kording , Edward S Boyden

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

We introduce a method to find network motifs in knowledge graphs. Network motifs are useful patterns or meaningful subunits of the graph that recur frequently. We extend the common definition of a network motif to coincide with a basic…

Machine Learning · Statistics 2021-04-19 Peter Bloem

Networks are a fundamental model of complex systems throughout the sciences, and network datasets are typically analyzed through lower-order connectivity patterns described at the level of individual nodes and edges. However, higher-order…

Social and Information Networks · Computer Science 2018-02-21 Austin R. Benson

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

Neurons and Cognition · Quantitative Biology 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser

Interaction networks are of central importance in post-genomic molecular biology, with increasing amounts of data becoming available by high-throughput methods. Examples are gene regulatory networks or protein interaction maps. The main…

Statistical Mechanics · Physics 2009-11-10 Johannes Berg , Michael Lässig

We develop a biophysical model of neuro-sensory integration in the model organism Caenorhabditis elegans. Building on recent experimental findings of the neuron conductances and their resolved connectome, we posit the first full dynamic…

Neurons and Cognition · Quantitative Biology 2015-06-17 James Kunert , Eli Shlizerman , J. Nathan Kutz

Physical and functional constraints on biological networks lead to complex topological patterns across multiple scales in their organization. A particular type of higher-order network feature that has received considerable interest is…

Quantitative Methods · Quantitative Biology 2024-10-15 Alexis Bénichou , Jean-Baptiste Masson , Christian L. Vestergaard