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Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

Machine Learning · Statistics 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Missing genotypes can affect the efficacy of machine learning approaches to identify the risk genetic variants of common diseases and traits. The problem occurs when genotypic data are collected from different experiments with different DNA…

Multi-view clustering aims at exploiting information from multiple heterogeneous views to promote clustering. Most previous works search for only one optimal clustering based on the predefined clustering criterion, but devising such a…

Machine Learning · Computer Science 2020-10-06 Shaowei Wei , Jun Wang , Guoxian Yu , Carlotta Domeniconi , Xiangliang Zhang

Clustering in high-dimensional spaces is a difficult problem which is recurrent in many domains, for example in image analysis. The difficulty is due to the fact that high-dimensional data usually live in different low-dimensional subspaces…

Statistics Theory · Mathematics 2016-08-16 Charles Bouveyron , Stéphane Girard , Cordelia Schmid

We address the problem of un-supervised soft-clustering called micro-clustering. The aim of the problem is to enumerate all groups composed of records strongly related to each other, while standard clustering methods separate records at…

Data Structures and Algorithms · Computer Science 2016-06-07 Takeaki Uno , Hiroki Maegawa , Takanobu Nakahara , Yukinobu Hamuro , Ryo Yoshinaka , Makoto Tatsuta

Summary: Accurate phenotype prediction from genomic sequences is a highly coveted task in biological and medical research. While machine-learning holds the key to accurate prediction in a variety of fields, the complexity of biological data…

Hierarchical clustering recursively partitions data at an increasingly finer granularity. In real-world applications, multi-view data have become increasingly important. This raises a less investigated problem, i.e., multi-view hierarchical…

Machine Learning · Computer Science 2022-05-06 Fangfei Lin , Bing Bai , Kun Bai , Yazhou Ren , Peng Zhao , Zenglin Xu

Understanding the global organization of complicated and high dimensional data is of primary interest for many branches of applied sciences. It is typically achieved by applying dimensionality reduction techniques mapping the considered…

Computational Geometry · Computer Science 2024-11-11 Paweł Dłotko , Davide Gurnari , Mathis Hallier , Anna Jurek-Loughrey

The explosive growth of complex datasets across various modalities necessitates advanced analytical tools that not only group data effectively but also provide human-understandable insights into the discovered structures. We introduce…

Machine Learning · Computer Science 2025-09-04 Gabor Petnehazi , Bernadett Aradi

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

Getting a robust time-series clustering with best choice of distance measure and appropriate representation is always a challenge. We propose a novel mechanism to identify the clusters combining learned compact representation of…

Machine Learning · Computer Science 2021-01-12 Soma Bandyopadhyay , Anish Datta , Arpan Pal

Clustering is a popular machine learning technique for data mining that can process and analyze datasets to automatically reveal sample distribution patterns. Since the ubiquitous categorical data naturally lack a well-defined metric space…

Machine Learning · Computer Science 2025-09-01 Yiqun Zhang , Mingjie Zhao , Hong Jia , Yang Lu , Mengke Li , Yiu-ming Cheung

Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

Machine Learning · Statistics 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

This paper introduces {\em fusion subspace clustering}, a novel method to learn low-dimensional structures that approximate large scale yet highly incomplete data. The main idea is to assign each datum to a subspace of its own, and minimize…

Machine Learning · Computer Science 2022-05-24 Usman Mahmood , Daniel Pimentel-Alarcón

Many fields, such as neuroscience, are experiencing the vast proliferation of cellular data, underscoring the need for organizing and interpreting large datasets. A popular approach partitions data into manageable subsets via hierarchical…

Quantitative Methods · Quantitative Biology 2024-03-07 Diek W. Wheeler , Giorgio A. Ascoli

Subspace clustering algorithms are used for understanding the cluster structure that explains the dataset well. These methods are extensively used for data-exploration tasks in various areas of Natural Sciences. However, most of these…

Machine Learning · Computer Science 2022-11-15 Ashutosh Singh , Ashish Singh , Aria Masoomi , Tales Imbiriba , Erik Learned-Miller , Deniz Erdogmus

Modern inference and learning often hinge on identifying low-dimensional structures that approximate large scale data. Subspace clustering achieves this through a union of linear subspaces. However, in contemporary applications data is…

Machine Learning · Computer Science 2018-08-03 Daniel L. Pimentel-Alarcón , Usman Mahmood

Clustering is widely used in different field such as biology, psychology, and economics. Most traditional clustering algorithms are limited to handling datasets that contain either numeric or categorical attributes. However, datasets with…

Databases · Computer Science 2019-07-03 Trupti M. Kodinariya Dr. Prashant R. Makwana

Real data are often with multiple modalities or from multiple heterogeneous sources, thus forming so-called multi-view data, which receives more and more attentions in machine learning. Multi-view clustering (MVC) becomes its important…

Machine Learning · Computer Science 2019-03-05 Menglei Hu , Songcan Chen