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Rooted binary phylogenetic networks are extensions of rooted binary trees, adding reticulation nodes that are designed to represent evolutionary processes that involve hybridization events. Enumerative combinatorics studies have counted…

Since Darwin, species trees have been used as a simplified description of the relationships which summarize the complicated network $N$ of reality. Recent evidence of hybridization and lateral gene transfer, however, suggest that there are…

Populations and Evolution · Quantitative Biology 2016-11-17 Stephen J. Willson

We describe a method that will reconstruct an unrooted binary phylogenetic level-1 network on n taxa from the set of all quartets containing a certain fixed taxon, in O(n^3) time. We also present a more general method which can handle more…

Combinatorics · Mathematics 2013-08-26 J. C. M. Keijsper , R. A. Pendavingh

Here we show that deciding whether two rooted binary phylogenetic trees on the same set of taxa permit a cherry-picking sequence, a special type of elimination order on the taxa, is NP-complete. This improves on an earlier result which…

Populations and Evolution · Quantitative Biology 2021-04-13 Janosch Döcker , Leo van Iersel , Steven Kelk , Simone Linz

In recent decades, phylogenetic networks have become a standard tool in modeling evolutionary processes. Nevertheless, basic combinatorial questions about them are still largely open. For instance, even the asymptotic counting problem for…

Combinatorics · Mathematics 2018-11-13 Michael Fuchs , Bernhard Gittenberger , Marefatollah Mansouri

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

Reconstructing the evolutionary past of a family of genes is an important aspect of many genomic studies. To help with this, simple operations on a set of sequences called orthology relations may be employed. In addition to being…

Discrete Mathematics · Computer Science 2016-03-16 K. T. Huber , G. E. Scholz

Phylogenetic networks are generalizations of trees that allow for the modeling of non-tree like evolutionary processes. Split networks give a useful way to construct networks with intuitive distance structures induced from the associated…

Combinatorics · Mathematics 2024-09-18 Bryson Kagy , Seth Sullivant

Phylogenomics commonly aims to construct evolutionary trees from genomic sequence information. One way to approach this problem is to first estimate event-labeled gene trees (i.e., rooted trees whose non-leaf vertices are labeled by…

Combinatorics · Mathematics 2019-05-09 Marc Hellmuth , Katharina T. Huber , Vincent Moulton

Polyploidization is an evolutionary process by which a species acquires multiple copies of its complete set of chromosomes. The reticulate nature of the signal left behind by it means that phylogenetic networks offer themselves as a…

Populations and Evolution · Quantitative Biology 2023-02-21 Katharina T. Huber , Liam J. Maher

It has remained an open question for some time whether, given a set of not necessarily binary (i.e. "nonbinary") trees T on a set of taxa X, it is possible to determine in time f(r).poly(m) whether there exists a phylogenetic network that…

Populations and Evolution · Quantitative Biology 2012-08-03 Steven Kelk , Celine Scornavacca

A normal (phylogenetic) network with $k$ reticulations displays $2^k$ phylogenetic trees. In this paper, we establish an analogous result for tree-child (phylogenetic) networks with no underlying $3$-cycles. In particular, we show that a…

Combinatorics · Mathematics 2025-08-20 Charles Semple , Kristina Wicke

Rearrangement operations transform a phylogenetic tree into another one and hence induce a metric on the space of phylogenetic trees. Popular operations for unrooted phylogenetic trees are NNI (nearest neighbour interchange), SPR (subtree…

Combinatorics · Mathematics 2019-12-24 Remie Janssen , Jonathan Klawitter

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

Genomics · Quantitative Biology 2007-05-23 Kerstin Hoef-Emden

This paper introduces the tensor representation of a network, here tensors are the primitive structures of the network. In view of tensor chains, two binary operations on tensor sets are defined: chain addition and reducing. Based on the…

Rings and Algebras · Mathematics 2022-03-15 Yanhui Wang , Dazhi Meng

Algebraic techniques in phylogenetics have historically been successful at proving identifiability results and have also led to novel reconstruction algorithms. In this paper, we study the ideal of phylogenetic invariants of the…

Algebraic Geometry · Mathematics 2025-09-29 Joseph Cummings , Elizabeth Gross , Benjamin Hollering , Samuel Martin , Ikenna Nometa

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers…

Populations and Evolution · Quantitative Biology 2023-04-07 Giulia Bernardini , Leo van Iersel , Esther Julien , Leen Stougie

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

Populations and Evolution · Quantitative Biology 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Orthologous genes, which arise through speciation, play a key role in comparative genomics and functional inference. In particular, graph-based methods allow for the inference of orthology estimates without prior knowledge of the underlying…

Populations and Evolution · Quantitative Biology 2025-02-14 Anna Lindeberg , Guillaume E. Scholz , Nicolas Wieseke , Marc Hellmuth

We associate root polytopes to directed graphs and study them by using ribbon structures. Most attention is paid to what we call the semi-balanced case, i.e., when each cycle has the same number of edges pointing in the two directions.…

Combinatorics · Mathematics 2024-08-16 Tamás Kálmán , Lilla Tóthmérész