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Matching patients to clinical trial options is critical for identifying novel treatments, especially in oncology. However, manual matching is labor-intensive and error-prone, leading to recruitment delays. Pipelines incorporating large…

Computation and Language · Computer Science 2025-09-25 Braxton A. Morrison , Madhumita Sushil , Jacob S. Young

This paper explores the potential of large language models (LLMs) as reliable analytical tools in linguistic research, focusing on the emergence of affective meanings in temporal expressions involving manner-of-motion verbs. While LLMs like…

Computation and Language · Computer Science 2025-07-15 Rosa Illan Castillo , Javier Valenzuela

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Recommender systems are widely used in online services, with embedding-based models being particularly popular due to their expressiveness in representing complex signals. However, these models often function as a black box, making them…

Information Retrieval · Computer Science 2024-06-25 Yuxuan Lei , Jianxun Lian , Jing Yao , Xu Huang , Defu Lian , Xing Xie

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Evaluating Large Language Models (LLMs) in open-ended scenarios is challenging because existing benchmarks and metrics can not measure them comprehensively. To address this problem, we propose to fine-tune LLMs as scalable judges (JudgeLM)…

Computation and Language · Computer Science 2025-03-04 Lianghui Zhu , Xinggang Wang , Xinlong Wang

Large Language Models (LLMs) are increasingly employed in software engineering tasks such as requirements elicitation, design, and evaluation, raising critical questions regarding their alignment with human judgments on responsible AI…

Software Engineering · Computer Science 2025-11-07 Asma Yamani , Malak Baslyman , Moataz Ahmed

In the face of rapidly expanding online medical literature, automated systems for aggregating and summarizing information are becoming increasingly crucial for healthcare professionals and patients. Large Language Models (LLMs), with their…

Computation and Language · Computer Science 2024-03-07 Niraj Yagnik , Jay Jhaveri , Vivek Sharma , Gabriel Pila

Evaluating generated radiology reports is crucial for the development of radiology AI, but existing metrics fail to reflect the task's clinical requirements. This study proposes a novel evaluation framework using large language models…

Computation and Language · Computer Science 2024-04-02 Zilong Wang , Xufang Luo , Xinyang Jiang , Dongsheng Li , Lili Qiu

Large Language Models (LLMs) are prone to generating content that exhibits gender biases, raising significant ethical concerns. Alignment, the process of fine-tuning LLMs to better align with desired behaviors, is recognized as an effective…

Computation and Language · Computer Science 2024-12-17 Tao Zhang , Ziqian Zeng , Yuxiang Xiao , Huiping Zhuang , Cen Chen , James Foulds , Shimei Pan

Large Language Models (LLMs) have demonstrated significant capabilities in machine translation. However, their translation quality is sometimes questioned, as the generated outputs may deviate from expressions typically used by native…

Computation and Language · Computer Science 2024-12-10 Ke-Ching Chang , Chung-Chi Chen , An-Zi Yen

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

This study presents a comprehensive analysis and comparison of two predominant fine-tuning methodologies - full-parameter fine-tuning and parameter-efficient tuning - within the context of medical Large Language Models (LLMs). We developed…

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability…

Computation and Language · Computer Science 2023-08-16 Xiaoming Shi , Jie Xu , Jinru Ding , Jiali Pang , Sichen Liu , Shuqing Luo , Xingwei Peng , Lu Lu , Haihong Yang , Mingtao Hu , Tong Ruan , Shaoting Zhang

Large Language Models (LLMs) excel in various Natural Language Processing (NLP) tasks, yet their evaluation, particularly in languages beyond the top $20$, remains inadequate due to existing benchmarks and metrics limitations. Employing…

Computation and Language · Computer Science 2024-02-14 Rishav Hada , Varun Gumma , Adrian de Wynter , Harshita Diddee , Mohamed Ahmed , Monojit Choudhury , Kalika Bali , Sunayana Sitaram

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Although large language models (LLMs) demonstrate expert-level medical knowledge, aligning their open-ended outputs with fine-grained clinician preferences remains challenging. Existing methods often rely on coarse objectives or unreliable…

Artificial Intelligence · Computer Science 2026-02-12 Shiwei Lyu , Xidong Wang , Lei Liu , Hao Zhu , Chaohe Zhang , Jian Wang , Jinjie Gu , Benyou Wang , Yue Shen