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It is becoming widely accepted that very early in the origin of life, even before the emergence of genetic encoding, reaction networks of diverse small chemicals might have manifested key properties of life, namely self-propagation and…

Populations and Evolution · Quantitative Biology 2023-01-05 Zhen Peng , Alex Plum , Praful Gagrani , David A. Baum

This thesis broadly concerns the origins of life problem, pursuing a joint approach that combines general philosophical/conceptual reflection on the problem along with more detailed and formal scientific modelling work oriented in the…

Other Quantitative Biology · Quantitative Biology 2016-06-14 Benjamin John Shirt-Ediss

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole

Even when concepts similar to emergence have been used since antiquity, we lack an agreed definition. However, emergence has been identified as one of the main features of complex systems. Most would agree on the statement ``life is…

General Physics · Physics 2025-12-22 Carlos Gershenson

The emergence of life from inanimate matter presents a thermodynamic challenge: the Second Law of Thermodynamics dictates a global trend towards disorder, yet life constitutes localized pockets of profound organization. This paper presents…

Statistical Mechanics · Physics 2026-03-17 Shlomo Segal

The molecular machinery of life is largely created via self-organisation of individual molecules into functional assemblies. Minimal coarse-grained models, where a whole macromolecule is represented by a small number of particles, can be of…

Biological Physics · Physics 2019-06-25 Anne E. Hafner , Johannes Krausser , Anđela Šarić

A universal framework is proposed, where all laws are regularities of relations between things or agents. Parts of the world at one or all times are modeled as networks called SYSTEMS with a minimum of axiomatic properties. A notion of…

High Energy Physics - Theory · Physics 2009-10-31 Gerhard Mack

The primordial confrontation underlying the existence of our universe can be conceived as the battle between entropy and complexity. The law of ever-increasing entropy (Boltzmann H-theorem) evokes an irreversible, one-directional evolution…

Physics and Society · Physics 2015-06-18 Sorin Solomon , Natasa Golo

Self-organization, the ability of a system of microscopically interacting entities to shape macroscopically ordered structures, is ubiquitous in Nature. Spatio-temporal patterns are abundantly observed in a large plethora of applications,…

Pattern Formation and Solitons · Physics 2019-06-17 Malbor Asllani , Timoteo Carletti , Duccio Fanelli , Philip K. Maini

Contemporary complexity theory has been instrumental in providing novel rigorous definitions for some classic philosophical concepts, including emergence. In an attempt to provide an account of emergence that is consistent with complexity…

Adaptation and Self-Organizing Systems · Physics 2015-02-06 Jonathan Lawhead

Self-organization in complex systems is a process in which randomness is reduced and emergent structures appear that allow the system to function in a more competitive way with other states of the system or with other systems. It occurs…

Adaptation and Self-Organizing Systems · Physics 2025-06-02 Matthew J Brouillet , Georgi Yordanov Georgiev

A phenomenological model of self-organization explaining the emergence of a complexity with features that apparently satisfy the specific criteria usually required for recognizing the appearance of life in laboratory is presented. The…

Adaptation and Self-Organizing Systems · Physics 2007-08-31 Erzilia Lozneanu , Mircea Sanduloviciu

Recent computational experiments have demonstrated the spontaneous emergence of self-replicating programs across universal automata, artificial chemistries, and self-modifying code systems. Remarkably, these results arise without explicit…

Logic in Computer Science · Computer Science 2026-01-27 Aritra Sarkar

In the paper we present results to develop an irreducible theory of complex systems in terms of self-organization processes of prime integer relations. Based on the integers and controlled by arithmetic only the self-organization processes…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Victor Korotkikh , Galina Korotkikh

Computation is commonly defined as the execution of abstract algorithms over symbolic representations, with physical systems treated as substrates that realise predefined operations. While effective for engineered machines, this separation…

Physics and Society · Physics 2026-01-21 Kimia Witte

Molecular interactions are wired in a fascinating way resulting in complex behavior of biological systems. Theoretical modeling provides a useful framework for understanding the dynamics and the function of such networks. The complexity of…

Computational Engineering, Finance, and Science · Computer Science 2010-02-23 Judit Zámborszky , Corrado Priami

A self-organization is an universal phenomenon in nature and, in particular, is highly important in materials systems and biology. We proposed a new theory that allowed us to model the most challenging cases of atomic self-assembling whose…

Other Condensed Matter · Physics 2014-11-25 M. Lavrskyi , H. Zapolsky , A. G. Khachaturyan

The dominant paradigm in origin of life research is that of an RNA world. However, despite experimental progress towards the spontaneous formation of RNA, the RNA world hypothesis still has its problems. Here, we introduce a novel…

Molecular Networks · Quantitative Biology 2017-01-31 Wim Hordijk

Hierarchy is one of the most conspicuous features of numerous natural, technological and social systems. The underlying structures are typically complex and their most relevant organizational principle is the ordering of the ties among the…

Physics and Society · Physics 2014-03-05 Tamás Nepusz , Tamás Vicsek

At odds with a traditional view of molecular evolution that seeks a descent-with-modification relationship between functional sequences, new functions can emerge {\it de novo} with relative ease. At early times of molecular evolution,…

Populations and Evolution · Quantitative Biology 2021-05-26 Susanna Manrubia