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Large language models (LLMs) have exerted a considerable impact on diverse language-related tasks in recent years. Their demonstrated state-of-the-art performance is achieved through methodologies such as zero-shot or few-shot prompting.…

Computation and Language · Computer Science 2023-12-21 Arshad Kaji , Manan Shah

While various models and computational tools have been proposed for structure and property analysis of molecules, generating molecules that conform to all desired structures and properties remains a challenge. Here, we introduce a…

Computation and Language · Computer Science 2024-10-11 Peng Zhou , Jianmin Wang , Chunyan Li , Zixu Wang , Yiping Liu , Siqi Sun , Jianxin Lin , Leyi Wei , Xibao Cai , Houtim Lai , Wei Liu , Longyue Wang , Yuansheng Liu , Xiangxiang Zeng

The remarkable advancements in large language models (LLMs) have brought about significant improvements in Natural Language Processing(NLP) tasks. This paper presents a comprehensive review of in-context learning techniques, focusing on…

Computation and Language · Computer Science 2023-09-26 Yinheng Li

There is increasing adoption of artificial intelligence in drug discovery. However, existing studies use machine learning to mainly utilize the chemical structures of molecules but ignore the vast textual knowledge available in chemistry.…

Machine Learning · Computer Science 2024-01-31 Shengchao Liu , Weili Nie , Chengpeng Wang , Jiarui Lu , Zhuoran Qiao , Ling Liu , Jian Tang , Chaowei Xiao , Anima Anandkumar

Large language models (LLMs) with in-context learning have demonstrated remarkable capability in the text-to-SQL task. Previous research has prompted LLMs with various demonstration-retrieval strategies and intermediate reasoning steps to…

Computation and Language · Computer Science 2023-11-28 Shuaichen Chang , Eric Fosler-Lussier

Large language models (LLMs) provide powerful means to leverage prior knowledge for predictive modeling when data is limited. In this work, we demonstrate how LLMs can use their compressed world knowledge to generate intrinsically…

Large Language Models (LLMs) are increasingly used as coding assistants. However, the ambiguity of the developer's prompt often leads to incorrect code generation, as current models struggle to infer user intent without extensive prompt…

Artificial Intelligence · Computer Science 2025-07-30 Harsh Darji , Thibaud Lutellier

The emerging zero-shot capabilities of Large Language Models (LLMs) have led to their applications in areas extending well beyond natural language processing tasks. In reinforcement learning, while LLMs have been extensively used in…

Advances in large language models (LLMs) have recently opened new and promising avenues for small-molecule drug discovery. Yet existing LLM-based approaches for molecular generation often suffer from high rates of invalid and low-quality…

Machine Learning · Computer Science 2026-05-15 Andrew Y. Zhou , Sharvaree Vadgama , Sumanth Varambally , Peter Eckmann , Michael K. Gilson , Rose Yu

Large Language Models (LLMs) have demonstrated remarkable proficiency in understanding and generating natural language. However, their capabilities wane in highly specialized domains underrepresented in the pretraining corpus, such as…

Machine Learning · Computer Science 2024-07-29 Junhong Shen , Neil Tenenholtz , James Brian Hall , David Alvarez-Melis , Nicolo Fusi

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

Quantitative Methods · Quantitative Biology 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Automating code documentation through explanatory text can prove highly beneficial in code understanding. Large Language Models (LLMs) have made remarkable strides in Natural Language Processing, especially within software engineering tasks…

Query expansion, pivotal in search engines, enhances the representation of user information needs with additional terms. While existing methods expand queries using retrieved or generated contextual documents, each approach has notable…

Information Retrieval · Computer Science 2024-03-29 Pengyue Jia , Yiding Liu , Xiangyu Zhao , Xiaopeng Li , Changying Hao , Shuaiqiang Wang , Dawei Yin

The field of machine learning (ML) has gained widespread adoption, leading to significant demand for adapting ML to specific scenarios, which is yet expensive and non-trivial. The predominant approaches towards the automation of solving ML…

Machine Learning · Computer Science 2024-02-20 Lei Zhang , Yuge Zhang , Kan Ren , Dongsheng Li , Yuqing Yang

The rapid evolution of Large Language Models (LLMs) has markedly expanded their application across diverse domains, transforming how complex problems are approached and solved. Initially conceived to predict subsequent words in texts, these…

Artificial Intelligence · Computer Science 2024-07-11 Sumedh Rasal , E. J. Hauer

Large language models (LLMs) have demonstrated increasingly sophisticated performance in medical and other fields of knowledge. Traditional methods of creating specialist LLMs require extensive fine-tuning and training of models on large…

Computation and Language · Computer Science 2025-02-25 Sean Wu , Michael Koo , Fabien Scalzo , Ira Kurtz

Prompt engineering has emerged as an indispensable technique for extending the capabilities of large language models (LLMs) and vision-language models (VLMs). This approach leverages task-specific instructions, known as prompts, to enhance…

Artificial Intelligence · Computer Science 2025-03-18 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Vinija Jain , Samrat Mondal , Aman Chadha

Large Language Models (LLMs) are nowadays extensively used for various types of software engineering tasks, primarily code generation. Previous research has shown how suitable prompt engineering could help developers in improving their code…

We propose to utilize an instruction-tuned large language model (LLM) for guiding the text generation process in automatic speech recognition (ASR). Modern large language models (LLMs) are adept at performing various text generation tasks…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-08 Yosuke Higuchi , Tetsuji Ogawa , Tetsunori Kobayashi

Large Language Models (LLMs) have shown remarkable capabilities in manipulating natural language across multiple applications, but their ability to handle simple reasoning tasks is often questioned. In this work, we aim to provide a…

Computation and Language · Computer Science 2025-05-05 Alessandro Raganato , Rafael Peñaloza , Marco Viviani , Gabriella Pasi