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To optimize diffusion MRI acquisition protocols for IMPULSED model at clinical 3T scanner using Bayesian experimental design, enabling accurate cellular-scale parameter estimation under realistic scan time and scanner hardware constraints.…

Quantitative MRI (qMRI) involves parameter estimation governed by an explicit signal model. However, these models are often confounded and difficult to validate in vivo. A model is misspecified when the assumed signal model differs from the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jiachen Wang , Jon Tamir , Adam Bush

Quantitative Magnetic Resonance Imaging (MRI) is based on a two-steps approach: estimation of the magnetic moments distribution inside the body, followed by a voxel-by-voxel quantification of the human tissue properties. This splitting…

Purpose: To develop neural network (NN)-based quantitative MRI parameter estimators with minimal bias and a variance close to the Cram\'er-Rao bound. Theory and Methods: We generalize the mean squared error loss to control the bias and…

Medical Physics · Physics 2024-05-07 Andrew Mao , Sebastian Flassbeck , Jakob Assländer

Quantitative Magnetic Resonance Imaging (qMRI) enables the reproducible measurement of biophysical parameters in tissue. The challenge lies in solving a nonlinear, ill-posed inverse problem to obtain the desired tissue parameter maps from…

Image and Video Processing · Electrical Eng. & Systems 2024-05-08 Felix F Zimmermann , Christoph Kolbitsch , Patrick Schuenke , Andreas Kofler

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…

Medical Physics · Physics 2025-01-17 Kaiyan Li , Prabhat Kc , Hua Li , Kyle J. Myers , Mark A. Anastasio , Rongping Zeng

The standard approach to compressive sampling considers recovering an unknown deterministic signal with certain known structure, and designing the sub-sampling pattern and recovery algorithm based on the known structure. This approach…

Information Theory · Computer Science 2016-02-03 Yen-Huan Li , Volkan Cevher

MRI is an inherently slow process, which leads to long scan time for high-resolution imaging. The speed of acquisition can be increased by ignoring parts of the data (undersampling). Consequently, this leads to the degradation of image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Soumick Chatterjee , Mario Breitkopf , Chompunuch Sarasaen , Hadya Yassin , Georg Rose , Andreas Nürnberger , Oliver Speck

Quantum Machine Learning (QML) has seen significant advancements, driven by recent improvements in Noisy Intermediate-Scale Quantum (NISQ) devices. Leveraging quantum principles such as entanglement and superposition, quantum convolutional…

Accurate and reliable Magnetic Resonance Imaging (MRI) analysis is particularly important for adaptive radiotherapy, a recent medical advance capable of improving cancer diagnosis and treatment. Recent studies have shown that IVIM-NET, a…

Hardware Architecture · Computer Science 2024-07-09 Zehuan Zhang , Matej Genci , Hongxiang Fan , Andreas Wetscherek , Wayne Luk

Self-supervised deep learning has accelerated 2D natural image analysis but remains difficult to translate into 3D MRI, where data are scarce and pre-trained 2D backbones cannot capture volumetric context. We present a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Dynamic Magnetic Resonance Imaging (MRI) is a crucial non-invasive method used to capture the movement of internal organs and tissues, making it a key tool for medical diagnosis. However, dynamic MRI faces a major challenge: long…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Tamir Shor , Chaim Baskin , Alex Bronstein

As a future trend of healthcare, personalized medicine tailors medical treatments to individual patients. It requires to identify a subset of patients with the best response to treatment. The subset can be defined by a biomarker (e.g.…

Methodology · Statistics 2021-08-16 Yitao Lu , Julie Zhou , Li Xing , Xuekui Zhang

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

Statistics Theory · Mathematics 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

Quantitative MRI (qMRI) is becoming increasingly important for research and clinical applications, however, state-of-the-art reconstruction methods for qMRI are computationally prohibitive. We propose a temporal multiscale approach to…

Optimization and Control · Mathematics 2021-03-31 Samuel Cortinhas , Mohammad Golbabaee , Matthias J. Ehrhardt

The SPARKLING algorithm was originally developed for accelerated 2D magnetic resonance imaging (MRI) in the compressed sensing (CS) context. It yields non-Cartesian sampling trajectories that jointly fulfill a target sampling density while…

Signal Processing · Electrical Eng. & Systems 2021-06-01 Chaithya G R , Zaccharie Ramzi , Philippe Ciuciu

Deep Learning (DL) methods can reconstruct highly accelerated magnetic resonance imaging (MRI) scans, but they rely on application-specific large training datasets and often generalize poorly to out-of-distribution data. Self-supervised…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Hongze Yu , Jeffrey A. Fessler , Yun Jiang

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Distribution network reconfiguration (DNR) has proved to be an economical and effective way to improve the reliability of distribution systems. As optimal network configuration depends on system operating states (e.g., loads at each node),…

Systems and Control · Electrical Eng. & Systems 2023-05-03 Mukesh Gautam , Narayan Bhusal , Mohammed Benidris
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