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Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Whole slide image (WSI) classification is an essential task in computational pathology. Despite the recent advances in multiple instance learning (MIL) for WSI classification, accurate classification of WSIs remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Saisai Ding , Jun Wang , Juncheng Li , Jun Shi

Recent advancements in pre-trained Vision-Language Models (VLMs) have highlighted the significant potential of prompt tuning for adapting these models to a wide range of downstream tasks. However, existing prompt tuning methods typically…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Xinyang Wang , Yi Yang , Minfeng Zhu , Kecheng Zheng , Shi Liu , Wei Chen

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

Few-shot, fine-grained classification in computer vision poses significant challenges due to the need to differentiate subtle class distinctions with limited data. This paper presents a novel method that enhances the Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Eric Brouwer , Jan Erik van Woerden , Gertjan Burghouts , Matias Valdenegro-Toro , Marco Zullich

Visual transfer learning for unseen categories presents an active research topic yet a challenging task, due to the inherent conflict between preserving category-specific representations and acquiring transferable knowledge. Vision-Language…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Xiao Shi , Yangjun Ou , Zhenzhong Chen

Foundation Vision-Language Models (VLMs) like CLIP exhibit strong generalization capabilities due to large-scale pretraining on diverse image-text pairs. However, their performance often degrades when applied to target datasets with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Debarshi Brahma , Soma Biswas

Vision Transformer (ViT) models have recently emerged as powerful and versatile models for various visual tasks. Recently, a work called PMF has achieved promising results in few-shot image classification by utilizing pre-trained vision…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Junjie Zhu , Yiying Li , Chunping Qiu , Ke Yang , Naiyang Guan , Xiaodong Yi

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Vision-language models have recently shown great potential on many tasks in computer vision. Meanwhile, prior work demonstrates prompt tuning designed for vision-language models could acquire superior performance on few-shot image…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Kun Ding , Ying Wang , Pengzhang Liu , Qiang Yu , Haojian Zhang , Shiming Xiang , Chunhong Pan

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Recently, CLIP-based approaches have exhibited remarkable performance on generalization and few-shot learning tasks, fueled by the power of contrastive language-vision pre-training. In particular, prompt tuning has emerged as an effective…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Balamurali Murugesan , Rukhshanda Hussain , Rajarshi Bhattacharya , Ismail Ben Ayed , Jose Dolz

Most advances in medical image recognition supporting clinical auxiliary diagnosis meet challenges due to the low-resource situation in the medical field, where annotations are highly expensive and professional. This low-resource problem…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Fudan Zheng , Jindong Cao , Weijiang Yu , Zhiguang Chen , Nong Xiao , Yutong Lu

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu
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