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Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Retrieval-augmented generation (RAG) is a promising way to improve large language models (LLMs) for generating more factual, accurate, and up-to-date content. Existing methods either optimize prompts to guide LLMs in leveraging retrieved…

Computation and Language · Computer Science 2024-12-12 Yutao Zhu , Zhaoheng Huang , Zhicheng Dou , Ji-Rong Wen

Large Language Models~(LLMs) are prone to hallucinations, and Retrieval-Augmented Generation (RAG) helps mitigate this, but at a high computational cost while risking misinformation. Adaptive retrieval aims to retrieve only when necessary,…

Retrieval-augmented generation (RAG) is a framework enabling large language models (LLMs) to enhance their accuracy and reduce hallucinations by integrating external knowledge bases. In this paper, we introduce a hybrid RAG system enhanced…

Computation and Language · Computer Science 2024-09-04 Ye Yuan , Chengwu Liu , Jingyang Yuan , Gongbo Sun , Siqi Li , Ming Zhang

Large Language Models (LLMs) showcase remarkable abilities, yet they struggle with limitations such as hallucinations, outdated knowledge, opacity, and inexplicable reasoning. To address these challenges, Retrieval-Augmented Generation…

Computation and Language · Computer Science 2024-10-03 Sourav Verma

Real-world live retrieval-augmented generation (RAG) systems face significant challenges when processing user queries that are often noisy, ambiguous, and contain multiple intents. While RAG enhances large language models (LLMs) with…

Computation and Language · Computer Science 2025-06-27 Guanting Dong , Xiaoxi Li , Yuyao Zhang , Mengjie Deng

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Retrieval-Augmented Generation (RAG) has emerged as a widely adopted approach for enhancing LLMs in scenarios that demand extensive factual knowledge. However, current RAG evaluations concentrate primarily on correctness, which may not…

Computation and Language · Computer Science 2026-03-23 Vinh Nguyen , Cuong Dang , Jiahao Zhang , Hoa Tran , Minh Tran , Trinh Chau , Thai Le , Lu Cheng , Suhang Wang

The advent of large language models (LLMs) has allowed numerous applications, including the generation of queried responses, to be leveraged in chatbots and other conversational assistants. Being trained on a plethora of data, LLMs often…

Computation and Language · Computer Science 2025-05-16 Deeksha Prahlad , Chanhee Lee , Dongha Kim , Hokeun Kim

Deploying Large Language Model (LLM) applications, particularly those relying on Retrieval-Augmented Generation (RAG), remains challenging due to high computational demands, outdated knowledge bases, and the need to manually select optimal…

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating up-to-date external knowledge, yet real-world web environments present unique challenges. These limitations manifest as two key challenges: pervasive…

Information Retrieval · Computer Science 2026-03-24 Yuqin Dai , Shuo Yang , Guoqing Wang , Yong Deng , Zhanwei Zhang , Jun Yin , Pengyu Zeng , Zhenzhe Ying , Changhua Meng , Can Yi , Yuchen Zhou , Weiqiang Wang , Shuai Lu

Recently, Large Language Models (LLMs) have been increasingly used to support various decision-making tasks, assisting humans in making informed decisions. However, when LLMs confidently provide incorrect information, it can lead humans to…

Information Retrieval · Computer Science 2025-10-16 Chaeyun Jang , Deukhwan Cho , Seanie Lee , Hyungi Lee , Juho Lee

Large Language Models (LLMs) have advanced artificial intelligence by enabling human-like text generation and natural language understanding. However, their reliance on static training data limits their ability to respond to dynamic,…

Artificial Intelligence · Computer Science 2026-04-02 Aditi Singh , Abul Ehtesham , Saket Kumar , Tala Talaei Khoei , Athanasios V. Vasilakos

Although the Retrieval-Augmented Generation (RAG) paradigms can use external knowledge to enhance and ground the outputs of Large Language Models (LLMs) to mitigate generative hallucinations and static knowledge base problems, they still…

Computation and Language · Computer Science 2024-05-24 Diji Yang , Jinmeng Rao , Kezhen Chen , Xiaoyuan Guo , Yawen Zhang , Jie Yang , Yi Zhang

Large Language Models are prompting us to view more NLP tasks from a generative perspective. At the same time, they offer a new way of accessing information, mainly through the RAG framework. While there have been notable improvements for…

Computation and Language · Computer Science 2025-03-21 Alex-Razvan Ispas , Charles-Elie Simon , Fabien Caspani , Vincent Guigue

Large Language Models (LLMs) have revolutionized natural language processing with their remarkable capabilities in text generation and reasoning. However, these models face critical challenges when deployed in real-world applications,…

Computation and Language · Computer Science 2025-09-16 Pengcheng Jiang , Siru Ouyang , Yizhu Jiao , Ming Zhong , Runchu Tian , Jiawei Han

Retrieval-Augmented Generation (RAG) systems using Multimodal Large Language Models (MLLMs) show great promise for complex document understanding, yet their development is critically hampered by inadequate evaluation. Current benchmarks…

Computation and Language · Computer Science 2025-08-06 Wenxuan Shen , Mingjia Wang , Yaochen Wang , Dongping Chen , Junjie Yang , Yao Wan , Weiwei Lin

Large Vision-Language Models (LVLMs) have made remarkable strides in multimodal tasks such as visual question answering, visual grounding, and complex reasoning. However, they remain limited by static training data, susceptibility to…

Artificial Intelligence · Computer Science 2025-08-27 Chan-Wei Hu , Yueqi Wang , Shuo Xing , Chia-Ju Chen , Suofei Feng , Ryan Rossi , Zhengzhong Tu

The data and compute requirements of current language modeling technology pose challenges for the processing and analysis of low-resource languages. Declarative linguistic knowledge has the potential to partially bridge this data scarcity…

Computation and Language · Computer Science 2024-10-02 Bhargav Shandilya , Alexis Palmer

Retrieval-Augmented Generation (RAG) systems enhance large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user needs. However, existing RAG systems…

Information Retrieval · Computer Science 2025-04-29 Zirui Guo , Lianghao Xia , Yanhua Yu , Tu Ao , Chao Huang
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