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Related papers: ProteinGPT: Multimodal LLM for Protein Property Pr…

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Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Large language models (LLMs) demonstrate impressive results in natural language processing tasks but require a significant amount of computational and memory resources. Structured matrix representations are a promising way for reducing the…

Computation and Language · Computer Science 2025-06-04 Ekaterina Grishina , Mikhail Gorbunov , Maxim Rakhuba

While large language models (LLMs) have made considerable advancements in understanding and generating unstructured text, their application in structured data remains underexplored. Particularly, using LLMs for complex reasoning tasks on…

Computation and Language · Computer Science 2023-10-18 Jiho Kim , Yeonsu Kwon , Yohan Jo , Edward Choi

Proteins are complex biomolecules that play a central role in various biological processes, making them critical targets for breakthroughs in molecular biology, medical research, and drug discovery. Deciphering their intricate, hierarchical…

Machine Learning · Computer Science 2025-05-09 Viet Thanh Duy Nguyen , Truong-Son Hy

In recent years, groundbreaking advancements in natural language processing have culminated in the emergence of powerful large language models (LLMs), which have showcased remarkable capabilities across a vast array of domains, including…

Computation and Language · Computer Science 2023-12-11 Microsoft Research AI4Science , Microsoft Azure Quantum

Attention-based models trained on protein sequences have demonstrated incredible success at classification and generation tasks relevant for artificial intelligence-driven protein design. However, we lack a sufficient understanding of how…

Machine Learning · Computer Science 2022-06-29 Erik Nijkamp , Jeffrey Ruffolo , Eli N. Weinstein , Nikhil Naik , Ali Madani

Large language models (LLMs) and multimodal models have become powerful general-purpose reasoning systems. However, radio-frequency (RF) signals, which underpin wireless systems, are still not natively supported by these models. Existing…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Hang Zou , Yu Tian , Bohao Wang , Lina Bariah , Samson Lasaulce , Chongwen Huang , Mérouane Debbah

Despite the rapid progress of Large Language Models (LLMs), their application in agriculture remains limited due to the lack of domain-specific models, curated datasets, and robust evaluation frameworks. To address these challenges, we…

Artificial Intelligence · Computer Science 2025-08-13 Bo Yang , Yu Zhang , Lanfei Feng , Yunkui Chen , Jianyu Zhang , Xiao Xu , Nueraili Aierken , Yurui Li , Yuxuan Chen , Guijun Yang , Yong He , Runhe Huang , Shijian Li

In recent years, significant progress has been made in the field of protein function prediction with the development of various machine-learning approaches. However, most existing methods formulate the task as a multi-classification…

Quantitative Methods · Quantitative Biology 2024-04-23 Hadi Abdine , Michail Chatzianastasis , Costas Bouyioukos , Michalis Vazirgiannis

Generating lifelike human motions from descriptive texts has experienced remarkable research focus in the recent years, propelled by the emerging requirements of digital humans.Despite impressive advances, existing approaches are often…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Yuan Wang , Di Huang , Yaqi Zhang , Wanli Ouyang , Jile Jiao , Xuetao Feng , Yan Zhou , Pengfei Wan , Shixiang Tang , Dan Xu

The rapid advancements in large language models (LLMs) have greatly expanded the potential for automated code-related tasks. Two primary methodologies are used in this domain: prompt engineering and fine-tuning. Prompt engineering involves…

Software Engineering · Computer Science 2025-02-21 Jiho Shin , Clark Tang , Tahmineh Mohati , Maleknaz Nayebi , Song Wang , Hadi Hemmati

Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

Machine Learning · Computer Science 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

With the emergence of Transformer architectures and their powerful understanding of textual data, a new horizon has opened up to predict the molecular properties based on text description. While SMILES are the most common form of…

Chemical Physics · Physics 2023-10-11 Suryanarayanan Balaji , Rishikesh Magar , Yayati Jadhav , Amir Barati Farimani

Recently, Multimodal Large Language Models (MLLMs) have gained significant attention for their remarkable ability to process and analyze non-textual data, such as images, videos, and audio. Notably, several adaptations of general-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Wenhui Zhu , Xin Li , Xiwen Chen , Peijie Qiu , Vamsi Krishna Vasa , Xuanzhao Dong , Yanxi Chen , Natasha Lepore , Oana Dumitrascu , Yi Su , Yalin Wang

Large language models (LLMs) have garnered considerable attention for their proficiency in tackling intricate tasks, particularly leveraging their capacities for zero-shot and in-context learning. However, their utility has been…

Biomolecules · Quantitative Biology 2024-05-14 Yiqing Shen , Outongyi Lv , Houying Zhu , Yu Guang Wang

The development of large language models (LLMs) such as ChatGPT has brought a lot of attention recently. However, their evaluation in the benchmark academic datasets remains under-explored due to the difficulty of evaluating the generative…

Computation and Language · Computer Science 2023-07-07 Md Tahmid Rahman Laskar , M Saiful Bari , Mizanur Rahman , Md Amran Hossen Bhuiyan , Shafiq Joty , Jimmy Xiangji Huang

Large Language Models (LLMs) employ three popular training approaches: Masked Language Models (MLM), Causal Language Models (CLM), and Sequence-to-Sequence Models (seq2seq). However, each approach has its strengths and limitations, and…

Machine Learning · Computer Science 2025-02-18 Xuefeng Liu , Songhao Jiang , Bo Li , Rick Stevens

With the emerging trend of GPT models, we have established a framework called AutoML-GPT that integrates a comprehensive set of tools and libraries. This framework grants users access to a wide range of data preprocessing techniques,…

Machine Learning · Computer Science 2023-09-06 Yun-Da Tsai , Yu-Che Tsai , Bo-Wei Huang , Chun-Pai Yang , Shou-De Lin

Protein-Text Question Answering (QA) is crucial for interpreting biological sequences through natural language. The integration of Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) that efficiently leverages biological…

Information Retrieval · Computer Science 2026-05-19 Li Ding , Duanyu Feng , Chen Huang , Yangshuai Wang , Yang Li , Wenqiang Lei , See-Kiong Ng

Protein-protein interactions (PPIs) are fundamental to numerous cellular processes, and their characterization is vital for understanding disease mechanisms and guiding drug discovery. While protein language models (PLMs) have demonstrated…

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