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Analog Compute-in-Memory (CiM) accelerators are increasingly recognized for their efficiency in accelerating Deep Neural Networks (DNN). However, their dependence on Analog-to-Digital Converters (ADCs) for accumulating partial sums from…

Hardware Architecture · Computer Science 2024-03-21 Shubham Negi , Utkarsh Saxena , Deepika Sharma , Kaushik Roy

We develop a layered quantum computer architecture, which is a systematic framework for tackling the individual challenges of developing a quantum computer while constructing a cohesive device design. We discuss many of the prominent…

In this paper, we propose FusionCIM, an operator-fusion-driven compute-in-memory (CIM) accelerator architecture for efficient and scalable LLM inference, with three key innovations: (1) a hybrid CIM pipeline architecture that maps QKT…

Hardware Architecture · Computer Science 2026-04-29 Zihao Xuan , Jia Chen , Yewen Li , Wei Xuan , Hegan Chen , Xiao Huo , Fengbin Tu

With the steady progress in quantum computing over recent years, roadmaps for upscaling quantum processors have relied heavily on the targeted qubit architectures. So far, similarly to the early age of classical computing, these designs…

Hardware Architecture · Computer Science 2022-08-01 Wan-Hsuan Lin , Bochen Tan , Murphy Yuezhen Niu , Jason Kimko , Jason Cong

We discuss a Quantum-Enhanced Computing Continuum, a heterogeneous, hybrid architecture that integrates quantum processing units (QPUs) within an Edge-Cloud-HPC fabric. Promote sustainability by shifting from performance to "energy-aware…

Emerging Technologies · Computer Science 2026-05-01 Carlos J. Barrios H. , Frédéric Le Mouël , Oscar Carrillo

Quantum optimal control can play a crucial role to realize a set of universal quantum logic gates with error rates below the threshold required for fault-tolerance. Open-loop quantum optimal control relies on accurate modeling of the…

Quantum Physics · Physics 2018-12-05 Guanru Feng , Franklin H. Cho , Hemant Katiyar , Jun Li , Dawei Lu , Jonathan Baugh , Raymond Laflamme

This article introduces a highly parallel algorithm for molecular dynamics simulations with short-range forces on single node multi- and many-core systems. The algorithm is designed to achieve high parallel speedups for strongly…

Computational Physics · Physics 2013-11-20 R. Meyer

Multiple linear regression assumes an imperative role in supervised machine learning. In 2009, Harrow et al. [Phys. Rev. Lett. 103, 150502 (2009)] showed that their HHL algorithm can be used to sample the solution of a linear system…

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

As quantum computing (QC) technologies mature, their integration into established high-performance computing (HPC) infrastructures is becoming a central objective for next-generation computing systems. However, unlocking the potential of…

The use of quantum processing units (QPUs) promises speed-ups for solving computational problems. Yet, current devices are limited by the number of qubits and suffer from significant imperfections, which prevents achieving quantum…

Quantum Physics · Physics 2023-06-08 Hila Safi , Karen Wintersperger , Wolfgang Mauerer

We propose, implement, and experimentally evaluate a runtime middleware to support high-throughput execution on hybrid cluster machines of large-scale analysis applications. A hybrid cluster machine consists of computation nodes which have…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-09-18 George Teodoro , Tony Pan , Tahsin M. Kurc , Jun Kong , Lee A. D. Cooper , Joel H. Saltz

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

Nucleus decompositions have been shown to be a useful tool for finding dense subgraphs. The coreness value of a clique represents its density based on the number of other cliques it is adjacent to. One useful output of nucleus decomposition…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-23 Jessica Shi , Laxman Dhulipala , Julian Shun

In the quest to reboot computing, quantum annealing (QA) is an interesting candidate for a new capability. While it has not demonstrated an advantage over classical computing on a real-world application, many important regions of the QA…

A scalable control architecture for superconducting quantum processors is essential as the number of qubits increases and coherent multi-qubit operations span beyond the capacity of a single control module. The Quantum Instrumentation…

Quantum Physics · Physics 2025-07-22 Agustin Silva , Alvaro Orgaz-Fuertes

Scaling up quantum computers to attain substantial speedups over classical computing requires fault tolerance. Conventionally, protocols for fault-tolerant quantum computation demand excessive space overheads by using many physical qubits…

Quantum Physics · Physics 2025-01-29 Hayata Yamasaki , Masato Koashi

Quantum computers promise to transform our notions of computation by offering a completely new paradigm. To achieve scalable quantum computation, optimizing compilers and a corresponding software design flow will be essential. We present a…

Programming Languages · Computer Science 2018-07-24 Thomas Häner , Damian S. Steiger , Krysta Svore , Matthias Troyer

High-performance computing (HPC) is essential for tackling complex computational problems across various domains. As the scale and complexity of HPC applications continue to grow, the need for scalable systems and software architectures…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-21 Risshab Srinivas Ramesh

A proposal for a magnetic quantum processor that consists of individual molecular spins coupled to superconducting coplanar resonators and transmission lines is carefully examined. We derive a simple magnetic quantum electrodynamics…

Materials Science · Physics 2016-11-02 M. D. Jenkins , D. Zueco , O. Roubeau , G. Aromí , J. Majer , F. Luis